Navigation Links
Anemone genes reveal versatile building blocks for body plans

The same set of genes responsible for establishing the bilateral body axes in animals as diverse as flies and frogs have been found to play an unexpected role in patterning an animal with a different body plan--a simple sea anemone.

Sea anemones, along with corals and jellyfish, are members of the phylum Cnidaria, and they possess a radial body plan that is distinct from the familiar bilateral body plan exhibited by vertebrates and many other animals. Despite their superficial dissimilarities, Cnidarians and other animals share a common ancestor--which existed over 500 million years ago--and, consequently, many genes. As illustrated by the new findings, scientists are now studying how these shared genes are used by radial and bilateral animals to learn how different body plans are determined and built at the molecular level, and how they arose during evolution.

The work is reported in the March 7th issue of Current Biology by David Matus and colleagues at the University of Hawaii and Stony Brook University.

To understand the evolution of body-plan patterning, the researchers isolated a particular set of genes from a tiny translucent cnidarian, the starlet sea anemone, Nematostella vectensis. The genes were the anemone's version of genes known to be responsible for organizing the dorso/ventral axis in bilateral animals.

Matus and colleagues found that two types of proteins--so-called TGFß ligands and an antagonist protein that functions in opposition to the ligands--encoded by these genes are expressed differently in anemones than they are in bilateral animals like flies and frogs. In those animals, the proteins are expressed on opposite sides of the dorsal/ventral axis very early in embryogenesis, during gastrulation. However, the researchers found that the anemone ligands and their antagonist protein are at first expressed together--then, as gastrulation proceeds, the proteins become segregated into different germ layers, with the TGFß ligands and downstream components deployed exclusively in the endoderm, or inner germ layer.

It therefore appears that the ancient, ancestral function for this signaling system may have been to determine the different germ layers of the developing embryo in animals that lacked a bilateral body plan. Over evolutionary time, the genes acquired a new and important role in establishing the dorso/ventral axis, eventually leading to the diversity of bilateral animals present today.


'"/>

Source:Cell Press


Related biology news :

1. Newly-discovered class of genes determines ?and restricts ?stem cell fate
2. Inexpensive, mass-produced genes core of synthetic biology advances at UH
3. First atlas of key brain genes could speed research on cancer, neurological diseases
4. U-M scientists find genes that control growth of common skin cancer
5. Researchers find missing genes of ancient organism
6. Scientists document complex genomic events leading to the birth of new genes
7. Genrate: a generative model that finds and scores new genes and exons in genomic microarray data
8. Advances in the characterisation of the oyster mushroom genes
9. Researchers find new genes necessary to make embryo
10. Protein helps regulate the genes of embryonic stem cells
11. Compounds in plastic packaging act as environmental estrogens altering breast genes
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:11/15/2016)... DUBLIN , Nov 15, 2016 Research ... - Global Forecast to 2021" report to their offering. ... ... reach USD 16.18 Billion by 2021 from USD 6.21 Billion in ... Growth of the bioinformatics market is driven by ...
(Date:6/22/2016)... 22, 2016   Acuant , the ... solutions, has partnered with RightCrowd ® ... Visitor Management, Self-Service Kiosks and Continuous Workforce ... add functional enhancements to existing physical access ... venues with an automated ID verification and ...
(Date:6/15/2016)... 2016 Transparency Market Research ... Market by Application Market - Global Industry Analysis Size Share ... the report, the  global gesture recognition market  was ... is estimated to grow at a CAGR of ... Increasing application of gesture recognition technology ...
Breaking Biology News(10 mins):
(Date:12/2/2016)... ... 2016 , ... PhUSE will build on the huge success ... Day Events (SDE) to organize a multiple-day US conference. The first annual US ... the pharmaceutical and life sciences industry will cover industry standards, data science, regulations ...
(Date:12/2/2016)... KING OF PRUSSIA, PA (PRWEB) , ... December 01, 2016 , ... ... clinical research is through industry-wide collaboration, standardization and a beautiful technology experience. All three ... which convened more than 100 clinical trial leaders from over 40 sponsor, CRO and ...
(Date:12/2/2016)... ... December 02, 2016 , ... The ... to collaboratively developing improved chemistry, manufacturing and control technologies for the pharmaceutical ... with robust, probe-based sampling. , Online liquid chromatography analysis is becoming ...
(Date:12/2/2016)... YORK , Dec. 1, 2016   SurePure, ... photopurification, announced today that the Company has concluded an ... the right for a 90-day period to acquire units ... value of approximately USD 3.7 million.  ... agreement with Tamarack under which Tamarack will seek regulatory ...
Breaking Biology Technology: