Navigation Links
Ancient fossil DNA found preserved in crystal

Scientists at the Weizmann Institute of Science recently discovered a new source of well-preserved ancient DNA in fossil bones. Their findings were published in the Proceedings of the National Academy of Sciences (PNAS).

Fossil DNA is a potential source of information on the evolution, population dynamics, migrations, diets and diseases of animals and humans. But if it is not well preserved or becomes contaminated by modern DNA, the results are uninterpretable.

The scientists, Prof. Steve Weiner and Michal Salamon of the Institute's Structural Biology Department, working in collaboration with Profs. Baruch Arensburg, Tel Aviv University, and Noreen Tuross, Harvard University, may have found a way to overcome these problems.

It was in 1986 that Weiner first reported the existence of crystal clusters in fresh bones. Even when these bones are ground up and treated with sodium hypochlorite ?a substance that removes all traces of organic matter ?the clusters of crystals remain intact and the organic material embedded in them is unaffected. Now, almost 20 years later, Weiner and Salamon have returned to these findings, reasoning that fossil bones might possess such crystal structures containing preserved ancient DNA.

After treating two modern and six fossil animal bones with the sodium hypo-chlorite, they found that DNA could be extracted from most of these crystal aggregates that is better preserved and contains longer fragments than DNA from untreated ground bone. The technique for reading the DNA worked better, as well, and the use of sodium hypochlorite reduces the possibility of modern contamination.

The crystal aggregates act as a "privileged niche in fossil bone," protecting the DNA from hostile environments and leaving it relatively undamaged over time. The team's findings suggest that the DNA in these aggregates should be preferred, whenever possible, over DNA from untreated bone.

This method holds much promise fo r the future analysis of ancient DNA in bones in yielding more reliable and authentic results than has previously been possible, and may help in unearthing the mysteries of our ancestral past.


'"/>

Source:American Committee for the Weizmann Institute of Science


Related biology news :

1. Ancient olfaction protein is shared by many bugs, offering new pest control target
2. Ancient immune defense mechanism is no match for HIV-1
3. Ancient DNA helps clarify the origins of two extinct New World horse species
4. Researchers Discover Ancient Origins Of Tuberculosis-causing Bacteria
5. Ancient DNA confirms single origin of Malagasy primates
6. Ancient anthropoid origins discovered in Africa
7. Ancient trans-Atlantic swarm brought locusts to the New World
8. Ancient humans brought bottle gourds to the Americas from Asia
9. Ancient DNA helps UF researchers unearth potential hemophilia therapy
10. Ancient DNA provides clues to the evolution of social behavior
11. Ancient ants arose 140-168 million years ago
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/28/2016)... 28, 2016 First quarter 2016:   ... compared with the first quarter of 2015 The gross ... M (loss: 18.8) and the operating margin was 40% (-13) ... Cash flow from operations was SEK 249.9 M (21.2) , ... is unchanged, SEK 7,000-8,500 M. The operating margin for ...
(Date:4/15/2016)... 15, 2016 Research and ... Biometrics Market 2016-2020,"  report to their offering.  , ... , ,The global gait biometrics market is expected ... the period 2016-2020. Gait analysis generates ... be used to compute factors that are not ...
(Date:3/29/2016)... LegacyXChange, Inc. (OTC: LEGX ... Protect are pleased to announce our successful effort to ... of writing instruments, ensuring athletes signatures against counterfeiting and ... athletes on LegacyXChange will be assured of ongoing proof ... Bill Bollander , CEO states, "By inserting ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... 23, 2016  Blueprint Bio, a company dedicated to ... medical community, has closed its Series A funding round, ... "We have received a commitment from Forentis ... need to meet our current goals," stated Matthew ... runway to complete validation on the current projects in ...
(Date:6/23/2016)... ... June 23, 2016 , ... ... at the Pennsylvania Convention Center and will showcase its product’s latest features from ... also be presenting a scientific poster on Disrupting Clinical Trials in The Cloud ...
(Date:6/23/2016)... -- Amgen (NASDAQ: AMGN ) today announced a ... sciences incubator to accelerate the development of new therapies ... QB3@953 was created to help high-potential life science and ... stage organizations - access to laboratory infrastructure. ... "Amgen Golden Ticket" awards, providing each winner with one ...
(Date:6/22/2016)... , June 22, 2016 Research and ... Global Markets" report to their offering. ... billion in 2014 from $29.3 billion in 2013. The market is ... of 13.8% from 2015 to 2020, increasing from $50.6 billion in ... projected product forecasts during the forecast period (2015 to 2020) are ...
Breaking Biology Technology: