Navigation Links
'Ancestral eve' was mother of all tooth decay

A New York University College of Dentistry (NYUCD) research team has found the first oral bacterial evidence supporting the dispersal of modern Homo sapiens out of Africa to Asia.

The team, led by Page Caufield, a professor of cariology and comprehensive care at NYUCD, discovered that Streptoccocus mutans, a bacterium associated with dental caries, has evolved along with its human hosts in a clear line that can be traced back to a single common ancestor who lived in Africa between 100,000 and 200,000 years ago.

S. mutans is transmitted from mothers to infants, and first appears in an infant’s mouth at about two years of age. Caufield’s findings are reported in an article in the February issue of the Journal of Bacteriology.

In his analysis of the bacterium, Caufield used DNA fingerprints and other biomarkers that scientists have also employed to trace human evolution back to a single common African ancestor, known as "ancestral Eve."

"As humans migrated around the world and evolved into the different races and ethnicities we know today," Caufield said, "this oral bacterium evolved with them in a simultaneous process called coevolution."

"It is relatively easy to trace the evolution of S. mutans, since it reproduces through simple cell division," says Caufield, who gathered over 600 samples of the bacterium on six continents over the past two decades. His final analysis focused on over 60 strains of S. mutans collected from Chinese and Japanese; Africans; African-Americans and Hispanics in the United States; Caucasians in the United States, Sweden, and Australia; and Amazon Indians in Brazil and Guyana.

"By tracing the DNA lineages of these strains," Caufield said, "We have constructed an evolutionary family tree with its roots in Africa and its main branch extending to Asia. A second branch, extending from Asia back to Europe, traces the migration of a small group of Asians who founded at least one group of modern-day Caucasians."

Additional branches, tracing the coevolution of humans and bacteria from Asia into North and South America, will be drawn in the next phase of Caufield’s analysis.

Source:New York University

Related biology news :

1. Adding Radiation Therapy To Chemotherapy Improves Survival In Patients With High-risk Breast Cancer
2. New Treatment Rivals Chemotherapy For Lymphoma, Study Finds
3. Bevacizumab Combined With Chemotherapy Improves Progression-Free Survival for Patients With Advanced Breast Cancer
4. Report that delayed motherhood decreases life expectancy of mouse offspring
5. Tendency to hair loss inherited from the mother
6. USC researchers determine mechanism of action of chemotherapy drug
7. Studies clarify risk factors for mother-to-child transmission of hepatitis C virus
8. Mining biotechs data mother lode
9. Gene expression profile helps predict chemotherapy response in ovarian cancer patients
10. Ultrasounds show mothers drinking shrinks fetal brain
11. Hyena mothers give their cubs a helpful dose of hormones

Post Your Comments:

(Date:6/21/2016)... 21, 2016 NuData Security announced today that ... of principal product architect and that Jon ... customer development. Both will report directly to ... moves reflect NuData,s strategic growth in its product ... customer demand and customer focus values. ...
(Date:6/15/2016)... 2016 Transparency Market Research ... Market by Application Market - Global Industry Analysis Size Share ... the report, the  global gesture recognition market  was ... is estimated to grow at a CAGR of ... Increasing application of gesture recognition technology ...
(Date:6/7/2016)... TORONTO , June 7, 2016  Syngrafii ... begun a business relationship that includes integrating Syngrafii,s ... pilot branch project. This collaboration will result in ... for the credit union, while maintaining existing document ... ...
Breaking Biology News(10 mins):
(Date:6/27/2016)... /PRNewswire/ - BIOREM Inc. (TSX-V: BRM) ("Biorem" or "the Company") ... shareholders, Clean Technology Fund I, LP and Clean Technology ... based venture capital funds which together hold approximately 59% ... diluted, as converted basis), that they have entered into ... holdings in Biorem to TUS Holdings Co. Ltd. ("TUS") ...
(Date:6/27/2016)... Diego, CA (PRWEB) , ... June 27, 2016 , ... ... solutions for clinical trials, announced today the Clinical Reach Virtual Patient Encounter ... their care circle with the physician and clinical trial team. , Using the CONSULT ...
(Date:6/27/2016)... 2016  Liquid Biotech USA ... a Sponsored Research Agreement with The University of ... from cancer patients.  The funding will be used ... with clinical outcomes in cancer patients undergoing a ... be employed to support the design of a ...
(Date:6/24/2016)... , June 24, 2016 Epic Sciences ... detects cancers susceptible to PARP inhibitors by targeting ... cells (CTCs). The new test has already been ... in multiple cancer types. Over 230 ... damage response pathways, including PARP, ATM, ATR, DNA-PK ...
Breaking Biology Technology: