Navigation Links
An advanced genetic diagnostic method for multiple myeloma

A researcher at the University of Navarra, Borja Sáez Ochoa, has proposed a new genetic diagnostic method for multiple myeloma (MM), a type of bone marrow cancer, which permits the detection of this disease in earlier stages.

The dissertation of this biologist, produced in the Department of Genetics of the School of Sciences of the University of Navarra, and in the Institute of Human Genetics of the University Hospital of Schleswig-Holstein, en Kiel (Germany), is oriented towards the study of the genetic base of this cancer, and the posterior development of cytogenetic diagnostic strategies for the detection of alterations with prognostic value.

For this purpose, he has analyzed, by means of statistical methods, the cytogenetic changes in a group of patients with MM. This methodology has permitted the discovery of associations between specific chromosomal changes, and thus the description of a new classification of the disease. In addition, the technique of hybridization in situ with fluorescence allowed him to identify new recurrent genetic changes that are involved in the appearance of this pathology.

A disease associated with old age

Multiple myeloma is a disease which primarily affects persons above 60 years of age. In 2001 in Spain, 1716 new cases were detected, and 1554 patients with the disease died, with 20 of these in Navarra. According to Borja Sáez, with the new methods of diagnosis developed through this research project, such as the FISH and FICTION strategies, we will be able to detect genetic alterations rapidly and easily in the early stages of the disease, permitting its early diagnosis. In addition, he emphasized that these procedures will promote the description of molecular targets for future, more effective treatments of MM.

These new techniques for genetic diagnosis of MM are already being applied in 20 hospitals in Spain. And in a not too distant future, these tests will permit us to offer each pat ient a treatment adapted to the genetic modifications that he or she presents, which, while they may not provide a cure for the disease, will make it possible to transform it into a chronic and asymptomatic pathology.


'"/>

Source:Elhuyar Fundazioa


Related biology news :

1. Researchers test new therapy for advanced melanoma
2. Agilent Technologies introduces advanced zebrafish, mouse microarrays for stem cell and developmental biology research
3. Combination therapy shows promising results in patients with advanced lung cancer
4. Molecular differences between early and advanced melanomas could provide new drug targets
5. Heavy multivitamin use may be linked to advanced prostate cancer
6. Its not all genetic: Common epigenetic problem doubles cancer risk in mice
7. Scientists detect probable genetic cause of some Parkinsons disease cases
8. Mouse brain tumors mimic those in human genetic disorder
9. Scientists identify genetic pathways essential to RNA interference
10. Researchers trace evolution to relatively simple genetic changes
11. Key mechanism in genetic inheritance during cell division identified
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/15/2017)... 15 2017   ivWatch LLC , a medical device company ... today announced receipt of its ISO 13485 Certification, the global standard ... Organization for Standardization (ISO®). ... Model 400 Continuous Monitoring device for the early detection of IV ... "This is an important milestone for ...
(Date:6/23/2017)... ARMONK, N.Y. and ITHACA, N.Y. ... IBM ) and Cornell University, a leader in dairy ... combined with bioinformatics designed to help reduce the chances ... breaches. With the onset of this dairy project, Cornell ... the Consortium for Sequencing the Food Supply Chain, a ...
(Date:5/16/2017)...  Veratad Technologies, LLC ( www.veratad.com ), an innovative ... verification solutions, announced today they will participate as a ... thru May 17, 2017, in Washington D.C.,s ... Identity impacts the lives of billions ... evolving digital world, defining identity is critical to nearly ...
Breaking Biology News(10 mins):
(Date:9/21/2017)... (PRWEB) , ... September 21, 2017 , ... ... scaffold technology, today announced the election of Paul Hermes, Entrepreneur in Residence at ... , Biorez has developed a proprietary, tissue-engineered scaffold for anterior cruciate ligament ...
(Date:9/20/2017)... ... September 20, 2017 , ... ... Huron Digital Pathology , a provider of whole slide imaging solutions, are ... conference . The workshop, entitled “Successfully Deploying a Best-in-Class Strategy for Digital Pathology,” ...
(Date:9/19/2017)... Charleston, SC (PRWEB) , ... September 19, 2017 ... ... Express, safely and accurately automates the most dangerous step of sample prep for ... digestion system to provide automation at an affordable price. The system is ideal ...
(Date:9/19/2017)... Pleasanton, Calif. and Washington, D.C. (PRWEB) , ... ... ... to delivering rapid care during an biological outbreak is about to be eliminated, ... When asked what makes ExcitePCR’s FireflyDX™ technologies different than other pathogen ...
Breaking Biology Technology: