Navigation Links
Allergy battle could be won in five years, says scientist

Researchers, working with colleagues at St George's, University of London, are developing drugs designed to stop allergens from entering the body, so rendering them harmless.

Professor David Garrod said the research ?recently shortlisted for the Northwest Regional Development Agency's Bionow Project of the Year ?takes a completely new approach to the treatment and prevention of allergies.

"The technology is based on our earlier discovery of how allergens, the substances that cause allergy, enter the body through the surface layer of cells that protect the skin and the tubes of the lungs," he said.

"Allergens from pollen or house dust mites are inhaled and then dissolve the binding material between the cells that form these protective linings; they can then enter the body by passing between the cells to cause an allergic response.

"The drugs we are developing -- called Allergen Delivery Inhibitors (ADIs) ?are designed to disable these allergens so they can no longer eat through the protective cell layer and block the allergic reaction before it occurs.

"The effect will be like avoiding allergens altogether. Removing carpets and rigorous cleaning of homes are established ways to avoid allergens, but they are only partially effective because their effects do not 'travel' with allergy sufferers.

"ADIs promise to be significantly better because taking a medicine is easier than rigorous housework and pills are portable."

Professor Garrod, who is based within Manchester's Faculty of Life Sciences, said work on the first ADI chemical was well advanced and potential drugs could enter clinical trials as early as 2010.

If successful, the drug would treat established symptoms already found in adult sufferers and, in due course, could be used to prevent allergies in children.

"Prevention of allergies has never before been possible," said Professor Garrod. "Current medicines don't act against the alle rgen at this early stage ?they only ease the symptoms ?so the development of these ADIs would be a major breakthrough in our fight against allergies."


'"/>

Source:University of Manchester


Related biology news :

1. Allergy cells can aggravate cancer and psoriasis
2. Allergy to hair dye increasing
3. UN environmental agency steps up battle against marine pollution
4. Chemists synthesize molecule that helps body battle cancers, malaria
5. A new molecule discovered in the battle between plants and disease
6. New weapon in battle against osteoporosis
7. Distinguishing friend from foe in the battle against cancer
8. Scientists find genes involved in the battle between Hessian flies and wheat
9. Protein discovery could unlock the secret to better TB treatment
10. Tiny particles could solve billion-dollar problem
11. First atlas of key brain genes could speed research on cancer, neurological diseases
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:11/21/2016)... , Nov. 21, 2016   Neurotechnology ... object recognition technologies, today announced that the MegaMatcher ... cards was submitted for the NIST Minutiae ... passed all the mandatory steps of the evaluation ... is a continuing test of fingerprint templates used ...
(Date:11/16/2016)... CLARA, Calif. , Nov. 16, 2016 ... enhancing user experience and security for consumer electronics, ... for the financial and retail industry, today announced ... secure and convenient way to authenticate users of ... uses Sensory,s TrulySecure™ software which requires ...
(Date:11/14/2016)... Nov. 14, 2016  Based on its ... Frost & Sullivan recognizes FST Biometrics with ... for Visionary Innovation Leadership. FST Biometrics emerged ... identification market by pioneering In Motion Identification ... instant, seamless, and non-invasive verification. This patented ...
Breaking Biology News(10 mins):
(Date:12/9/2016)... York , December 9, 2016 ... that the top five players in the  Global Label-Free ... in the overall market in 2015. Players such as ... Elmer have remained dominant in the global market due ... to ensure product innovation. Product upgrades and timely product ...
(Date:12/9/2016)... , Dec. 9, 2016 China Cord Blood Corporation ... China,s leading provider of cord blood collection, ... services, today announced the results of its 2016 Annual General ... Kong S.A.R., China . ... ratified the re-appointment of KPMG Huazhen LLP as the independent ...
(Date:12/9/2016)... According to a new market research report ... Reagent Equipment), Application (Research, PCR, Gene, DNA, NGS, Diagnostic, RNAI), End ... the global market is expected to reach USD 2.20 Billion by ... 10.6% during the forecast period. Continue ... ...
(Date:12/8/2016)... -- This report analyzes the worldwide markets for Biostimulants in ... & Fulvic), Extract Based, and Others. The report also analyzes ... Turf, Row Crops, and Others. The report provides separate comprehensive ... Japan , Europe , ... and Rest of World. Annual estimates and forecasts are provided ...
Breaking Biology Technology: