Navigation Links
Allergy battle could be won in five years, says scientist

Researchers, working with colleagues at St George's, University of London, are developing drugs designed to stop allergens from entering the body, so rendering them harmless.

Professor David Garrod said the research ?recently shortlisted for the Northwest Regional Development Agency's Bionow Project of the Year ?takes a completely new approach to the treatment and prevention of allergies.

"The technology is based on our earlier discovery of how allergens, the substances that cause allergy, enter the body through the surface layer of cells that protect the skin and the tubes of the lungs," he said.

"Allergens from pollen or house dust mites are inhaled and then dissolve the binding material between the cells that form these protective linings; they can then enter the body by passing between the cells to cause an allergic response.

"The drugs we are developing -- called Allergen Delivery Inhibitors (ADIs) ?are designed to disable these allergens so they can no longer eat through the protective cell layer and block the allergic reaction before it occurs.

"The effect will be like avoiding allergens altogether. Removing carpets and rigorous cleaning of homes are established ways to avoid allergens, but they are only partially effective because their effects do not 'travel' with allergy sufferers.

"ADIs promise to be significantly better because taking a medicine is easier than rigorous housework and pills are portable."

Professor Garrod, who is based within Manchester's Faculty of Life Sciences, said work on the first ADI chemical was well advanced and potential drugs could enter clinical trials as early as 2010.

If successful, the drug would treat established symptoms already found in adult sufferers and, in due course, could be used to prevent allergies in children.

"Prevention of allergies has never before been possible," said Professor Garrod. "Current medicines don't act against the alle rgen at this early stage ?they only ease the symptoms ?so the development of these ADIs would be a major breakthrough in our fight against allergies."


'"/>

Source:University of Manchester


Related biology news :

1. Allergy cells can aggravate cancer and psoriasis
2. Allergy to hair dye increasing
3. UN environmental agency steps up battle against marine pollution
4. Chemists synthesize molecule that helps body battle cancers, malaria
5. A new molecule discovered in the battle between plants and disease
6. New weapon in battle against osteoporosis
7. Distinguishing friend from foe in the battle against cancer
8. Scientists find genes involved in the battle between Hessian flies and wheat
9. Protein discovery could unlock the secret to better TB treatment
10. Tiny particles could solve billion-dollar problem
11. First atlas of key brain genes could speed research on cancer, neurological diseases
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/27/2017)... ROCKVILLE CENTRE, N.Y. , March 27, 2017 ... by Healthcare Information and Management Systems Society (HIMSS) ... Analytics Outpatient EMR Adoption Model sm . In ... top 12% of U.S. hospitals using an electronic ... recognized CHS for its high level of EMR ...
(Date:3/24/2017)... -- Research and Markets has announced the addition of ... - Industry Forecast to 2025" report to their offering. ... The Global Biometric Vehicle ... around 15.1% over the next decade to reach approximately $1,580 million ... estimates and forecasts for all the given segments on global as ...
(Date:3/23/2017)... Research and Markets has announced the addition of the ... to 2025" report to their offering. ... The Global Vehicle Anti-Theft System Market ... the next decade to reach approximately $14.21 billion by 2025. ... for all the given segments on global as well as regional ...
Breaking Biology News(10 mins):
(Date:10/10/2017)... ... October 10, 2017 , ... ... program has won a US2020 STEM Mentoring Award. Representatives of the FirstHand program ... in Volunteer Experience from US2020. , US2020’s mission is to change the trajectory ...
(Date:10/10/2017)... ... October 10, 2017 , ... ... 13 prestigious awards honoring scientists who have made outstanding contributions ... scheduled symposium during Pittcon 2018, the world’s leading conference and exposition for laboratory ...
(Date:10/9/2017)... , ... October 09, 2017 ... ... on October 5, 2017, in the medical journal, Epilepsia, Brain Sentinel’s SPEAC® ... gold standard, video EEG, in detecting generalized tonic-clonic seizures (GTCS) using surface ...
(Date:10/6/2017)... ... October 06, 2017 , ... On Tuesday, October 24th, ... INSIGhT, the first-ever adaptive clinical trial for glioblastoma (GBM). The featured speaker will ... free and open to the public, but registration is required. , WHAT: ...
Breaking Biology Technology: