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Affymetrix Launches New Globin-Reduction Kits and Protocol Developed with PreAnalytiX

ation as it relates to different disease states and a patient's response to drug therapy," said Noel Doheny, Vice President of PreAnalytiX and QIAGEN. "We continue to see a strong market trend towards the correlation of gene expression profiles of whole blood and tissue samples. With the new GeneChip Globin-Reduction Protocol and associated reagent kits, standardization of the entire pre-analytical and analytical process for whole blood gene expression profiling can now be accomplished."

"The ability of the PAXgene(TM) Blood RNA system to preserve RNA expression levels from the time of sample collection to the time of RNA isolation is a critical component to obtaining accurate gene expression profiles," said Lianne McLean, Sr. Director, Gene Expression Marketing, Affymetrix. "The optimized protocol, the PAXgene system and the controls will significantly improve the ability to obtain high quality profiles from blood, thus enabling clinical research and collecting samples for multi-site clinical trials."

About PreAnalytiX GmbH:

The purpose of PreAnalytiX GmbH, a Swiss-based joint venture between BD (Becton, Dickinson and Company) and QIAGEN N.V., is to develop, manufacture, and market integrated systems for the collection, stabilization, and purification of nucleic acids (DNA and RNA) for molecular diagnostic testing. The first product from PreAnalytiX, the PAXgene(TM) Blood RNA System, was launched in April 2001, and has set a new standard for stabilizing whole blood cellular RNA profiles at the time of blood collection in an evacuated blood collection tube. This enables researchers and clinicians to perform more accurate analysis of gene expression profiles without the variations caused by sample collection, storage, transport or fractionation while relying on highly standardized and proven sample collection principles. Additional information on PreAnalytiX can be found under http://www.preanalytix.com .

About Affymetrix:

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