Navigation Links
Affymetrix Launches New Globin-Reduction Kits and Protocol Developed with PreAnalytiX

Affymetrix Inc. (Nasdaq: AFFX), announced today the launch of the new GeneChip(R) Globin-Reduction kits and associated protocol developed in conjunction with PreAnalytiX -- a joint venture between QIAGEN N.V. (Nasdaq: QGEN; Frankfurt, Prime Standard: QIA) and BD (Becton, Dickinson and Company). The new kits optimize the PreAnalytiX PAXgene(TM) Blood RNA System for use with Affymetrix GeneChip technology and improve gene expression profile results of cellular RNA extracted from whole blood.

The combination of the GeneChip Blood RNA Concentration Kit (featuring the PAXgene Blood RNA System) and the GeneChip Globin-Reduction RNA Controls standardizes all the steps of whole blood RNA processing -- from sample stabilization to analysis on GeneChip microarrays. This has been a major challenge in expression studies of whole blood, as prior RNA preparation methods have often yielded expression results with variable levels of sensitivity.

Use of the Globin-Reduction Protocol and associated reagent kits enables researchers to detect subtle changes in gene expression by reducing the overwhelming amounts of globin messenger RNA (mRNA) present in whole blood. Large amounts of globin mRNA can significantly interfere with gene expression assay results. High globin mRNA levels contributed from a fraction of the red blood cells have typically masked the less abundant, but more important, changes of gene expression associated with white blood cells, such as lymphocytes and monocytes. Counteracting the effects of globin mRNA during target preparation significantly increases assay sensitivity on GeneChip arrays.

The GeneChip Globin Reduction Protocol links PreAnalytiX' already proven standard for whole blood collection, stabilization and isolation of RNA with Affymetrix' leading product line for microarray-based analysis of whole blood cellular RNA profiles.

"An accurate picture of in vivo gene expression profiles is essential for understanding gene regul
'"/>

Source:Affymetrix


Page: 1 2 3

Related biology news :

1. Affymetrix Unveils Plans to Double Plant and Animal Genome Microarray Offering
2. New Study from Affymetrix Laboratories Points to Changing View of How Genome Works
3. Affymetrix and the Karolinska Institutet Announce Translational Medicine Strategic Alliance
4. Affymetrix and Stratagene Announce Strategic Software Alliance
5. Affymetrix Licenses Microfluidics Technology From Caliper Life Sciences
6. Affymetrix and bioMerieux Extend Their Agreement on GeneChip(R) Technology to Breast Cancer Diagnostics
7. Affymetrix and ParAllele Launch Industrys Most Comprehensive Product Line for Targeted Genotyping
8. Genomatix Microarray Analysis Pipeline achieves Affymetrix GeneChip compatible?status
9. Affymetrix 500K array used to identify memory gene
10. Kinovate Life Sciences Launches Nittophase?High Performance Solid Support For Oligonucleatide Synthesis
11. IMF Launches World’s First DNA Database for Myeloma Patients
Post Your Comments:
(Date:9/2/2014)... When you accidentally touch a hot oven, you rapidly ... neural circuits involved in sensing and responding to such ... players. , Duke researchers have made a surprising discovery ... pain in worms, and have built a structural model ... Nature Communications , may help direct new strategies ...
(Date:9/1/2014)... the U.S. diet showed some modest improvement in the ... in the consumption of unhealthy trans fats, but the ... and the poor. , , An unhealthy diet is ... Eating a healthy diet is an important part of ... trends in diet quality is important because it can ...
(Date:9/1/2014)... the alteration of a single nucleotidethe basic building block of DNAcould ... disability. The study appears in The Journal of Cell ... by a defect in a gene on the X chromosome called ... 230 women and 1 in 360 men carry a so-called premutation, ... the FMR1 gene is slightly longer than normal. These ...
Breaking Biology News(10 mins):Surprising new role for calcium in sensing pain 2Surprising new role for calcium in sensing pain 3Quality of US diet improves, gap widens for quality between rich and poor 2Quality of US diet improves, gap widens for quality between rich and poor 3A nucleotide change could initiate fragile X syndrome 2
... University today announced a partnership to advance the use ... alternative energy source. The effort involves entrepreneurs John ... biodiesel in Afghanistan as a means to achieve multiple ... a new, sustainable economy in the country. ...
... understand the effects of climate change on the microbial ... and the tundra in Alaska, a University of Oklahoma ... of Energy grant. According to Jizhong Zhou, OU ... Institute for Environmental Genomics, the results of these studies ...
... demand for naturally raised beef continues to increase, researchers ... raised beef can be produced effectively for this niche ... to cover additional production and transportation costs. Naturally ... traditional systems take advantage of technologies the industry offers ...
Cached Biology News:Syracuse University partners with Arden-Fox to advance DOD's Net Zero Energy Initiative 2Syracuse University partners with Arden-Fox to advance DOD's Net Zero Energy Initiative 3Can naturally raised beef find its place in the industry? 2
(Date:8/29/2014)... Livermore, California (PRWEB) August 29, 2014 ... Department of Energy's 2014 Hydrogen Production R&D ... photoelectrochemically -- by splitting water using sunlight. , ... Laboratory (NREL) and the University of Nevada, Las ... its work developing models of photoelectrochemical solar-hydrogen production ...
(Date:8/29/2014)... A major challenge before new biotechnology start-up ... of Boston-Cambridge, is gaining visibility that can lead to ... Director of Boston’s Adult Stem Cell Technology Center, LLC ... of his company an important priority since he started ... a social media marketing campaign launched earlier ...
(Date:8/28/2014)... 2014 SPIE Fellow Glenn Boreman, Professor ... Science and Director of the Center for Optoelectronics and ... Charlotte, and co-founder and Chairman of the Board of ... 2015 Vice President of SPIE, the international society for ... announced recent election results at the Annual General Meeting ...
(Date:8/28/2014)... Best Sanitizers, Inc., the first company ... sanitizer, asks food processors and food handling professionals to ... they’re currently using to Best Sanitizers’ Alpet® E3 ... to fighting cross-contamination and the spread of pathogens in ... are key criteria that make a hand sanitizer most ...
Breaking Biology Technology:Livermore Team Awarded for Hydrogen Production Research 2The Adult Stem Cell Technology Center, LLC Participates in Multiple Stem Cell and Regenerative Medicine Conferences Before Year End 2The Adult Stem Cell Technology Center, LLC Participates in Multiple Stem Cell and Regenerative Medicine Conferences Before Year End 3The Adult Stem Cell Technology Center, LLC Participates in Multiple Stem Cell and Regenerative Medicine Conferences Before Year End 4Glenn Boreman, UNC Professor and Plasmonics Co-Founder, Elected to SPIE Presidential Chain 2Food Processors and Food Handlers are Encouraged to Prepare for Fall Harvest by Evaluating Their Current Hand Sanitizer Using Nine Key Criteria 2Food Processors and Food Handlers are Encouraged to Prepare for Fall Harvest by Evaluating Their Current Hand Sanitizer Using Nine Key Criteria 3
... Wisconsin landed a federal research laboratory too long, many observers might ... Madison in 1910 when Gifford Pinchot, the first chief of the ... National Wildlife Health Center , established in Madison in 1975, has ... race against bird flu. , ,The latest addition is the ...
... NimbleGen Systems scientist Thomas Albert will lead a ... microarray technology in DNA sequence analysis, the company announced. ... be the lead investigator on a two-year, $415,000 grant ... million Cancer Genome Atlas pilot project. , ,His work ...
... the scandals of WorldCom, ENRON, and TYCO were heartless and greedy, ... on this video make them look like saints. Why? Because the ... make a living to support their families. , ,Think about all ... of years that have not been able to find a good ...
Cached Biology Technology:Federal bioenergy lab will give Wisconsin a chance to shine 2Federal bioenergy lab will give Wisconsin a chance to shine 3Federal bioenergy lab will give Wisconsin a chance to shine 4A disgusting video: U.S. companies sell out Americans 2A disgusting video: U.S. companies sell out Americans 3A disgusting video: U.S. companies sell out Americans 4
... The product contains 5 ... coated with the monoclonal BerEP4 ... EpCAM (epithelial cell adhesion molecule). ... samples of 2 x 10e7 ...
albumin from bovine serum (BSA), BODIPY® FL conjugate...
GFX PCR DNA,Gel Band Purif,100, 1 EA. Category: Nucleotide Sample Handling....
... Services are uniquely positioned to ... current competitive environment. Invitrogens experts ... express, purify, and characterize proteins ... Studies, Activity Assays, X-ray Crystallography, ...
Biology Products: