Navigation Links
Adult stem cells from human cord umbilical cord blood successfully engineered to make insulin

In a fundamental discovery that someday may help cure type 1 diabetes by allowing people to grow their own insulin-producing cells for a damaged or defective pancreas, medical researchers here have reported that they have engineered adult stem cells derived from human umbilical cord blood to produce insulin.

The researchers announced their laboratory finding, which caps nearly four years of research, in the June 2007 issue of the medical journal Cell Proliferation, posted online this week. Their paper calls it "the first demonstration that human umbilical cord blood-derived stem cells can be engineered" to synthesize insulin.

"This discovery tells us that we have the potential to produce insulin from adult stem cells to help people with diabetes," said Dr. Randall J. Urban, senior author of the paper, professor and chair of internal medicine at the University of Texas Medical Branch at Galveston and director of UTMB’s Nelda C. and Lutcher H. J. Stark Diabetes Center. Stressing that the reported discovery is extremely basic research, Urban cautioned: "It doesn’t prove that we’re going to be able to do this in people — it’s just the first step up the rung of the ladder."

The lead author of the paper, UTMB professor of internal medicine/endocrinology Larry Denner, said that by working with adult stem cells rather than embryonic stem cells, doctors practicing so-called regenerative medicine eventually might be able to extract stem cells from an individual’s blood, then grow them in the laboratory to large numbers and tweak them so that they are directed to create a needed organ. In this way, he said, physicians might avoid the usual pitfall involved in transplanting cells or organs from other people — organ rejection, which requires organ recipients to take immune-suppressing drugs for the rest of their lives.

Huge numbers of stem cells are thought to be required to create new organs. Researchers might remove thousands of donor c
'"/>

Source:University of Texas Medical Branch at Galveston


Page: 1 2 3

Related biology news :

1. New Finding May Aid Adult Stem Cell Collection
2. Adult stem cells aid recovery in animal model of cerebral palsy
3. Adult stem cells are touchy-feely, need environmental clues
4. Adult stem cell research at UB targets damaged hearts
5. Adults who go to bed lonely get stress hormone boost next morning
6. Wisconsin scientists grow critical nerve cells
7. Spleen may be source of versatile stem cells
8. Researchers discover way to make cells in the eye sensitive to light
9. Priming embryonic stem cells to fulfill their promise
10. Lack of enzyme turns fat cells into fat burners
11. Poor prenatal nutrition permanently damages function of insulin-producing cells in the pancreas
Post Your Comments:
(Date:4/8/2015)...  Infinisource, a leading provider of SaaS-based Human Capital ... leading supplier of biometric identification and security solutions, ... advanced biometrically-enabled time clock, the companies announced today. ... setting a bold, new standard for the collection ... and mid-size employer. When connected to the iSolved ...
(Date:4/2/2015)... April 2, 2015 In ... by far outperforms the strongest competitors, showing outstanding ... accuracy, the system is capable of a throughput ... proves up to be ten times faster than ... runner-up performance.      (Photo: http://photos.prnewswire.com/prnh/20150402/738673-a ...
(Date:4/2/2015)... GOTHENBURG, Sweden , April 2, 2015 ... revenues for Q1 2015 attributed to somewhat higher than ... company in the year-end report 2014 that revenues for ... MSEK that the company reported for Q4 2014. The ... continue to be negative. The complete interim report will ...
Breaking Biology News(10 mins):iSolved Time Clock Offers Unmatched Accuracy due to Morpho Biometrics 2iSolved Time Clock Offers Unmatched Accuracy due to Morpho Biometrics 3DERMALOG AFIS Emerges as Performance Winner in NIST Benchmark Test 2DERMALOG AFIS Emerges as Performance Winner in NIST Benchmark Test 3Fingerprint Cards Revises Revenues for Q1 2015 2
... 17, 2009 Representatives of the nation,s leading public ... and other Members of Congress, today announced the launch ... research and related activities that have been made possible ... (ARRA), also known as the stimulus. The ...
... be as intelligent as much bigger animals, despite only ... scientists at Queen Mary, University of London. "Animals ... to Lars Chittka, Professor of Sensory and Behavioural Ecology ... of Cambridge colleague, Jeremy Niven. This begs the important ...
... Two University of New Hampshire assistant professors ... Early Career Development (CAREER) grants. Vaughn Cooper of ... received $1 million to better understand beneficial mutations ... data collection. Christopher White of the mechanical engineering ...
Cached Biology News:Members of Congress, university leaders, scientists launch ScienceWorksForUS 2Members of Congress, university leaders, scientists launch ScienceWorksForUS 3Members of Congress, university leaders, scientists launch ScienceWorksForUS 4Bigger not necessarily better, when it comes to brains 22 UNH faculty receive $1.4M in CAREER grants from NSF 2
(Date:4/24/2015)... April 24, 2015 Leading Regenerative ... in its allogeneic stem-cell product development program and ... reflect the corporate strategic direction. , “I am ... adipose stem cell development program has been kicked ... cGMP manufacturing facility and hiring of our new ...
(Date:4/24/2015)... , April 24, 2015 /CNW Telbec/ - Mirego, leader in ... the making of three mobile app extensions for the all ... for its clients, Familiprix, OMSignal and MediaMiser, these extensions will ... to functions designed specifically for wrist use.  ... Watch is a highly customizable tactile smartwatch that makes for ...
(Date:4/23/2015)... 2015 Ralco announced today that it ... (ABN) for the exclusive worldwide rights to sell and ... is a new in-line milk system that increases the ... to move supplementation milk cups within a farrowing facility ... technology lets producers get Birthright™ milk to the right ...
(Date:4/23/2015)... -- BioTE Medical President and Founder Gary Donovitz ... - Avoiding Over-Medication through Natural Hormone Balance" (ISBN: 9780990706458) ... at JW Marriott / Ritz Carlton Grande Lakes April ... Happier, is a welcomed response to many men and ... higher quality of life thanks to bio-identical hormone replacement ...
Breaking Biology Technology:Vet-Stem, Inc. Meets New Milestones and Changes Name to VetStem Biopharma 2Familiprix, OMSignal and MediaMiser apps available today for Apple Watch 2Ralco Acquires License to Birthright™ Moveable Milk Cup 2Release and Book Signing of BioTE Medical President Gary Donovitz M.D. 'Age Healthier Live Happier' at Age Management Medicine Group (AMMG) Conference 2Release and Book Signing of BioTE Medical President Gary Donovitz M.D. 'Age Healthier Live Happier' at Age Management Medicine Group (AMMG) Conference 3
... Talent Management Vendor,s Model ... Market, OTTAWA, Feb. 26 /PRNewswire/ - Halogen Software ... management software,today announced that FactPoint Group has profiled Halogen ... market. The Silicon Valley based research and,consulting firm selected ...
... Inc., a company focused,on developing novel therapies targeting ... Bussineau, Ph.D., to the,position of vice president of ... vice president, business development and nonvascular,operations., "Dr. ... experience to,BioVascular that will allow us to advance ...
... Ambrx Inc. today announced the,appointment of Douglas ... Clinical Research and Development., Axelrod joins Ambrx ... Procter & Gamble Pharmaceuticals. Most recently, he served ... and Product,Development where he accelerated the discovery process, ...
Cached Biology Technology:FactPoint Group Recognizes Halogen for "On-Choice" Deployment Model 2BioVascular, Inc. Expands Executive Team 2Ambrx Appoints Douglas Axelrod Senior Vice President for Clinical Research and Development 2
... Sphingobeads are designed for ... and characterize sphingosine binding proteins. ... 1 mL of agarose beads ... bound through the terminus of ...
... PolarScreen Androgen Receptor (AR) Competitor Assay Kits ... studying and screening potential AR ligands using ... AR ligand binding domain protein tagged with ... novel, selective fluorescent androgen ligand (Fluormone AL ...
... Plus is a chemiluminescent signal enhancing ... to boost the signal obtained with ... kits. ChemiLucent™ Plus is derived from ... conjugated complex- or chemiluminescent substrate enhancers, ...
... proteomic scale kinase profiling, quantitative measurement ... discovery research built on the flexible ... platform. These microarrays are available as ... Substrate - Peptide Microarray Service. ...
Biology Products: