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Adding radiation decreases breast cancer recurrence

cer Research Network.

They found that women, regardless of age or comorbidities, who underwent breast conserving surgery but no radiotherapy, were more likely to have recurrence of disease or develop additional breast tumors compared to women who received breast conserving surgery and radiation or mastectomy alone. The risk was highest for local and regional recurrence. These results held regardless of tamoxifen treatment, suggesting that adjuvant radiation treatment was highly effective.

In addition, the researchers found that women who received less than one year of tamoxifen were more likely to have disease recurrence or develop additional breast tumors compared to women who completed the recommended five year course.

Based on these study findings, the authors "recommend that mastectomy or breast conserving surgery with radiation therapy, along with adequate duration of adjuvant hormonal therapy for hormone-responsive tumors, be considered standard therapy in women of all ages and comorbidities, excepting those with very limited life expectancies."
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Source:John Wiley & Sons, Inc.


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