Navigation Links
Acidity in the brain could hold the key to stroke treatment

Development of a new technique for detecting brain damage caused by stroke has been boosted up by a £1m grant to scientists at The University of Manchester. Professor Gareth Morris of the School of Chemistry and Professor Risto Kauppinen of the University of Birmingham are to lead the development of a new non-invasive technique which measures acidity (pH) in the brain.

A stroke is caused when part of the blood supply to the brain is cut off. This causes acidity in the brain to build up, leading to damage.

CT scans are currently used to detect bleeding, swelling and tumours in the brain, but the visibility of soft tissue is very limited, making damage difficult to detect.

Professors Morris and Kauppinen will use advanced Nuclear Magnetic Resonance (NMR) technologies to allow MRI scanners to create detailed images of pH in the brain.

The images will be used to compare healthy (neutral, pH 7) and damaged (acidic, lower pH) areas of the brain, and to measure how the pH of the brain changes over time, with the aim of providing more targeted and effective treatments.

Professor Morris said: "Within two to three years we hope to have developed an NMR technique which can be translated into a machine that can image acidity in the brain.

"If we can map stroke damage accurately, doctors will have a better chance to provide more targeted and effective treatment. Current techniques often only enable one to see damage once it is too late to intervene."

NMR will be used to measure the rate at which hydrogen ions are exchanged between water and proteins in the brain. Acidity causes this rate to increase, changing the NMR signal of water.


'"/>

Source:University of Manchester


Page: 1

Related biology news :

1. Controversial drug shown to act on brain protein to cut alcohol use
2. Mouse brain cells rapidly recover after Alzheimers plaques are cleared
3. Mouse brain tumors mimic those in human genetic disorder
4. New imaging method gives early indication if brain cancer therapy is effective, U-M study shows
5. First atlas of key brain genes could speed research on cancer, neurological diseases
6. NYU study reveals how brains immune system fights viral encephalitis
7. Stem cells from brain transformed to produce insulin at Stanford
8. Birds brains reveal source of songs
9. Loves all in the brain: fMRI study shows strong, lateralized reward, not sex, drive
10. Revolutionary nanotechnology illuminates brain cells at work
11. A puzzle piece found in unraveling the wiring of the brain
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Acidity the brain could hold the key stroke treatment

(Date:10/17/2014)... University of Copenhagen have shown for the first time ... Cystic fibrosis patients, giving them the opportunity to get ... infections. , The study also discovered the bacterial growth ... was halted or slowed down by the immune cells. ... oxygen and helped "suffocate" the bacteria, forcing the bacteria ...
(Date:10/16/2014)... synthesis of recent research findings to inform their management ... states. , The Ecology and Management of Moist ... of the Relevant Biophysical Science and Implications for Future ... U.S. Forest Service,s Pacific Northwest Research Station, is a ... synthesis of the large body of scientific information on ...
(Date:10/16/2014)... – Post-menopausal women experienced improvements in vaginal atrophy, ... genital bleeding, after 12 weeks of daily 10 ... germ-based nutritional supplement previously shown to help relieve ... pilot study reported in a poster at the ... , "These data documented improved vaginal epithelium, ...
Breaking Biology News(10 mins):Scientists opens black box on bacterial growth in cystic fibrosis lung infection 2New report synthesizes best available science on management of moist mixed-conifer forests 2S-equol supplements associated with improved measures of reproductive health in postmenopausal women 2
... Feb. 29 /Xinhua-PRNewswire/ -- Futronic Technology Company,Limited, ... hardware products,today announced that the latest version ... and Windows 2008 Server., FinLogon is ... using proprietary fingerprint recognition technology. By a,finger ...
... of impact strata on Mars, Holden Crater; Eocene-Oligocene ... that liquid water is not responsible for recent ... Cretaceous early Albian greenhouse conditions and implications for ... Earth,s copper supply; discovery of large nitrate pools ...
... biochemistry, has received the National Science Foundation,s prestigious ... competitive funding award, designed to support the integrated ... their careers, is bestowed on those scientists and ... leaders of the 21st century. Fewer than 20 ...
Cached Biology News:Futronic Announces Microsoft Vista and Windows 2008 Server Support for Its Fingerprint Logon Software 2March GEOLOGY and GSA TODAY media highlights 2March GEOLOGY and GSA TODAY media highlights 3March GEOLOGY and GSA TODAY media highlights 4March GEOLOGY and GSA TODAY media highlights 5March GEOLOGY and GSA TODAY media highlights 6March GEOLOGY and GSA TODAY media highlights 7March GEOLOGY and GSA TODAY media highlights 8March GEOLOGY and GSA TODAY media highlights 9March GEOLOGY and GSA TODAY media highlights 10March GEOLOGY and GSA TODAY media highlights 11March GEOLOGY and GSA TODAY media highlights 12March GEOLOGY and GSA TODAY media highlights 13March GEOLOGY and GSA TODAY media highlights 14March GEOLOGY and GSA TODAY media highlights 15UD's Bobev receives NSF Early Career Award for research on novel compounds of rare Earth metals 2UD's Bobev receives NSF Early Career Award for research on novel compounds of rare Earth metals 3
(Date:10/20/2014)... , October 20, 2014 , ... (GI) disorders and the delivery of care has revealed ... and worrying inequalities in the provision of healthcare services ... was commissioned by United European Gastroenterology (UEG), have been ... and public awareness of the burden of GI disorders ...
(Date:10/20/2014)... October 20, 2014 Earle ... LLC, announced today that Ellen Teplitzky, an experienced ... for the pharmaceutical industry, has joined the firm ... its legal services practice. NDA Partners provides ... witness and testimony, to top law firms and ...
(Date:10/19/2014)... Mass. , Oct. 19, 2014 NextCODE Health, ... the whole genome in real time, today announced the launch ... NextCODE Exchange , at the American Society of Human ... . To learn more, sign up and apply for free ... its unique features and benefits can be viewed here ...
(Date:10/19/2014)... October 19, 2014 The report "Chocolate, ... Share, Trade, Prices, Geography Trend and Forecast (2011 - ... category, and geography and studies the major market drivers, ... America, Europe, and Asia. , The global chocolate market ... $98.3 billion in 2016 at an estimated CAGR of ...
Breaking Biology Technology:Major Survey Reveals Changing Trends and Inequalities in Healthcare Provision for Gastrointestinal Disorders Across Europe 2Major Survey Reveals Changing Trends and Inequalities in Healthcare Provision for Gastrointestinal Disorders Across Europe 3Major Survey Reveals Changing Trends and Inequalities in Healthcare Provision for Gastrointestinal Disorders Across Europe 4Major Survey Reveals Changing Trends and Inequalities in Healthcare Provision for Gastrointestinal Disorders Across Europe 5NDA Partners Appoints Ellen Teplitzky, JD as Director of its Legal Services Practice 2The NextCODE Exchange: The first global, real-time system for sharing full-resolution genomic data 2The NextCODE Exchange: The first global, real-time system for sharing full-resolution genomic data 3Chocolate Market Projected To Reach $98.3 Billion by 2016 - New Report by MarketsandMarkets 2Chocolate Market Projected To Reach $98.3 Billion by 2016 - New Report by MarketsandMarkets 3Chocolate Market Projected To Reach $98.3 Billion by 2016 - New Report by MarketsandMarkets 4
... and Mayo Foundation,for Medical Education and Research announced ... systems biology (CSB(TM)) profiling to,breast cancer patient stratification. ... profile test to improve diagnosis and treatment for ... an exciting research and development,program with Mayo, a ...
... E. Nedwin, Ph.D., MBA to Join Genencor,s Senior ... Genencor, a division of Danisco,A/S, today announced that ... as,Executive Vice President - Technical Enzymes, effective Oct. ... Management Team, Dr. Nedwin will head the,division,s activities ...
... MUNICH, Germany, October 1 - New Product ... - Approval Requested in 28 European Countries DAIICHI ... for,approval of a new antihypertensive medication. It is a ... (ARB),Olmesartan and the calcium antagonist Amlodipin. When approved, ...
Cached Biology Technology:Genencor Appoints New Executive Vice President - Technical Enzymes 2DAIICHI SANKYO EUROPE is Applying for Approval of its New Combination Product of Olmesartan and Amlodipin 2
APO-BrdU™ TUNEL Assay Kit *with Alexa Fluor® 488 anti-BrdU* *60 assays*...
...
IMAGEQUANT 300 IQTL, 1 EA. Category: ImageQuant CCD Imagers....
RayBio Human Cytokine Antibody Array 1.1 (4 array membranes) with Accessory, detects 20 cytokines (for lysate) Class: Antibody Array Products Product Group: Antibody Array...
Biology Products: