Navigation Links
AIDS drug from sunflowers

Sunflowers can produce a substance which prevents the AIDS pathogen HIV from reproducing, at least in cell cultures. This is the result of research carried out by scientists at the University of Bonn in cooperation with the caesar research centre. For several years now the hopes for a completely new group of AIDS drugs have been pinned to what is known as 'DCQA'. However, the substance is only available in very small quantities and is thus extremely expensive. By using the Bonn method it could probably be produced for a fraction of the costs. The researchers have patented their method. Together with the J├╝lich Research Centre they now want to attempt to manufacture the substance on a large scale. They are looking for partners in industry to help them with this.

It all began with a small mould with the tongue-twisting name sclerotinia sclerotiorum. The pathogen responsible for the dreaded 'white stem rot' can, if the weather conditions are unfavourable, destroy an entire sunflower crop. However, some sunflowers survive the fungus attack more or less unscathed. They do this by producing specific antibodies which eventually put a stop to the fungus.

The agricultural engineer Claudio Cerboncini wanted to find out what chemical weapons the fungus-resistant sunflowers have at their disposal. In his PhD thesis for Professor Heide Schnabl of the Bonn Centre of Molecular Biotechnology (CEMBIO) Claudio infected different types with their sworn enemy. In this way he was able to isolate the antitoxins which the plants produce in response to the fungus. Among these was a substance which is also mentioned in the literature, albeit in a completely different context: this is dicaffeoyl quinic acid, or DCQA for short ?the highly prized prototype for a new group of AIDS drugs.

One million euros per gram

'Dicaffeoyl quinic acid can prevent the HI virus from reproducing, at least in cell cultures,' explains Claudio Cerboncini, who is now
'"/>

Source:University of Bonn


Page: 1 2 3

Related biology news :

1. Novel Asthma Study Shows Multiple Genetic Input Required; Single-gene Solution Shot Down
2. Novel technology detects human DNA mutations
3. Novel antiviral technology inhibits RSV infection in mice
4. Novel Enzyme Shows Potential As An Anti-HIV Target
5. Novel Therapy Tested in Mice Could Chase Away Cat Allergies
6. Discovery Could Lead To Novel Approaches In HIV Treatment
7. Novel ultrafast laser detection of cancer cells also may improve understanding of stem cells
8. Research Using Mouse Models Reveals A Novel Key Player In The Initiation Of Colon Cancer
9. Novel gene-silencing nanoparticles shown to inhibit Ewings sarcoma
10. Novel live reporting system to track cells
11. Field of beams - Novel system uses polarized light pulses to reveal crop health
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: AIDS drug from sunflowers

(Date:7/11/2014)... Salk Institute for Biological Studies, BGI, and other ... and reliability of the existing targeted gene correction ... which could significantly increased gene-correction efficiency in human ... online in Cell Stell Cell provides ... therapy. , The combination of stem cells and ...
(Date:7/11/2014)... July 11, 2014 Researchers have pioneered ... images. The new technology, called Virtual Finger, allows ... structures like neurons and synapses using the flat ... technology makes 3D imaging studies orders of magnitude ... an unprecedented level across many areas of experimental ...
(Date:7/11/2014)... the normal circumstances, astrocytes participate in normal ... and exhibit therapeutic and repairing effects on ... have found that nerve cells differentiated from ... reduced viability, which produces influences on subsequent ... General Hospital, Hebei United University, China demonstrated ...
Breaking Biology News(10 mins):A new genome editing method brings the possibility of gene therapies closer to reality 2Virtual finger enables scientists to navigate and analyze complex 3D images 2
... COLUMBUS, Ohio From the paleolithic diet to the raw ... they believe our ancient ancestors ate. But some of these ... new book on the evolution of the use of food and ... can learn from what our ancestors ate, many of our more ...
... E. coli food poisoning outbreaks developed more ... trials because of lack of commercial interest. University of ... neutralises the toxin produced by E. coli , which ... The team of scientists Dr Adrienne Paton, Associate Professor ...
... to phase out nuclear power by 2022 has reopened an ... Japan, which is still coming to terms with events at ... the SETAC journal Environmental Toxicology and Chemistry adds ... using research from the Chernobyl disaster. The issue ...
Cached Biology News:An 'all natural' diet? There's no such thing 2An 'all natural' diet? There's no such thing 3Potential treatment for deadly E. coli disease 2
(Date:7/10/2014)... , July 10, 2014  Franciscan ... use of capnography for respiratory monitoring outside ... of healthcare leaders in embracing state-of-the-art patient ... effectively patients are breathing and can alert ... By measuring the amount of carbon dioxide ...
(Date:7/10/2014)... -- Research and Markets ( http://www.researchandmarkets.com/research/s3bqj2/photonic ) has ... Integrated Circuit (Monolithic Integration, Hybrid Integration, Module Integration) ... their offering. http://photos.prnewswire.com/prnh/20130307/600769 ... traces its roots in the latter half of ... went unexplored and unfulfilled for several decades owing ...
(Date:7/10/2014)... D.C., June 17, 2014 Using microscopic polymer ... specific gases, researchers at MIT,s Quantum Photonics Laboratory ... levels in the parts-per-billion range. Optical sensors are ... their high signal-to-noise ratio, compact, lightweight nature, and ... gas sensors had been developed before, the MIT ...
(Date:7/10/2014)... lithium-ion batteries that power our laptops and electric vehicles ... single charge with the help of a sponge-like silicon ... replace the graphite traditionally used in one of the ... the energy storage capacity of graphite. A paper describing ... published today in Nature Communications . , "Silicon ...
Breaking Biology Technology:Franciscan St. Anthony Health-Crown Point Underscores Patient Safety Commitment Through Expanded Use of Capnography 2International Photonic Integrated Circuit (Monolithic Integration, Hybrid Integration, Module Integration) Market - Forecasts to 2019 2Swell new sensors 2Silicon sponge improves lithium-ion battery performance 2Silicon sponge improves lithium-ion battery performance 3
... Dimensions , a Wisconsin data management firm, announced last ... the New York metro area by partnering with MailSurity ... company that develops paper scanning and data recognition technology, ... its software to process forms. , ,Parascript's software is ...
... rude noise somebody makes in a meeting after too ... population also knows that Enterprise Resource Planning isnt some ... single check to a vendor. , ,Im not out ... is apparently less obvious is that ERP systems dont ...
... provider of rich-media systems and software, is deploying its ... announced. , ,Sonic Foundry and media services provider ... Connect's new Virtual Law Viewer system for the ... MediaSite presentation recorders with the BxVideo RMXPRES hosting services, ...
Cached Biology Technology:Steering a project portfolio takes more than expensive software 2Steering a project portfolio takes more than expensive software 3Streaming video could make courtrooms into Internet conference calls 2
... product contains 5 ml Dynabeads Tosylactivated (4.5 ... (tosyl) reactive groups. For coupling of antibodies ... on initial coupling with covalent binding of ... sulphydryll groups (SH)) occurringovernight. Coupling reactions can ...
Carrier-Free Recombinant Human Flt-3/Flk-2 Ligand (Flt3/Flk2 Ligand, Flt3L, Flt3-L, Flk2L, Flk2-L) 100 ug...
... II inhibitor (IC50 = 59.2 M). ... H 32 O 13 MolWeight: ... RT CAS: ... Soluble to 100 mM in DMSO ...
NAP-2 (5C7)...
Biology Products: