Navigation Links
A sweet solution for Alzheimer's disease?

uccessfully in the same type of mice used in the scyllo-inositol studies, but the vaccine turned out to be toxic in some humans. It caused an autoimmune reaction in about 10 percent of patients who were immunized, St George-Hyslop said.

Autoimmune responses shouldn't be a problem with scyllo-inositol. "This compound works by a different mechanism and doesn't involve immunizing a patient with his own protein, which was probably the origin of the allergic reaction to the vaccine," the researcher said.

Another complication with previous attempts to treat Alzheimer's disease has been that some compounds--such as beta secretase inhibitors--cannot enter the brain easily, St George-Hyslop explained. Scyllo-inositol, on the other hand, readily passes through the blood-brain barrier where it is made available to the central nervous system.

Even if scyllo-inositol does prove safe and effective in humans, patients will likely still need drugs designed to attack other aspects of Alzheimer's pathology, such as tau neurofibrillary tangles, St George-Hyslop said.

"Alzheimer's disease is probably going to be treated by a cocktail of drugs," he predicted. "Some of them might be this compound, or one like it, that blocks the toxicity and aggregation of amyloid."


'"/>

Source:Howard Hughes Medical Institute


Page: 1 2 3

Related biology news :

1. Bad aftertaste? New sensory on/off switch may cure bane of artificial sweetener search
2. Bitter or sweet? The same taste bud can tell the difference
3. UW-Madison scientists zero in on drugs sweet spots
4. Sweet water taste paradoxically predicts sweet taste inhibitors
5. Scientists seek to unwrap the sweet mystery of the sugar coat on bacteria
6. Healing honey: The sweet evidence revealed
7. Attacking cancers sweet tooth is effective strategy against tumors
8. Uncovering DNAs sweet secret
9. A sweet step toward new cancer therapies
10. New law for resolution allows unprecedented sharpness in fluorescence microscopy
11. A radical solution for environmental pollution
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: sweet solution for Alzheimer disease