Navigation Links
A surprise about our body clock

Researchers at the McEwen Centre for Regenerative Medicine at Toronto General Hospital have discovered the 'SOS' distress signal that mobilizes specific heart repair cells from the bone marrow to the injured heart after a heart attack.

While it has long been known that bone marrow cells have the ability to clear the dead tissue after a heart attack, what has not been known until now is the critically important role of bone marrow adult stem cells in repairing a damaged heart, restoring its function and enhancing the growth of new blood vessels.

"These cells act like generals in a battlefield, explained Dr. Shafie Fazel, cardiac surgery resident at TGH, University of Toronto surgeon/scientist program fellow and lead author of the study entitled, "Cardioprotective c-kit+ cells are from the bone marrow and regulate the myocardial balance of angiogenic cytokines," published today in The Journal of Clinical Investigation. "When damaged heart tissue sends out an 'SOS' distress signal, this subset of bone marrow cells mobilizes quickly and stimulates the growth of new blood vessels in the heart. This is the first step in repairing the heart and in preventing the vicious downward spiral of heart failure in which the heart progressively thins and dilates, eventually causing death." Despite advances in surgical procedures, mechanical assistance devices, drug therapy, and organ transplantation, more than half of patients with congestive heart failure die within five years of initial diagnosis.

"Cardiovascular diseases are the most important cause of mortality in Canada and the western world," said Dr. Ren-Ke Li, scientist at the McEwen Centre for Regenerative Medicine and Professor of Cardiovascular Surgery at the University of Toronto. "Each year, 70,000 Canadians suffer from a heart attack and many of them are left with crushing disabilities, mainly because the heart muscle is not able to regenerate after a heart attack. This study identifies the metho
'"/>

Source:jill.woods@hci.utah.edu


Page: 1 2 3

Related biology news :

1. First real-time view of developing neurons reveals surprises, say Stanford researchers
2. Researchers make surprise discovery that some neurons can transmit three signals at once
3. Census of Marine Life explorers surprised by diversity, density of Arctic creatures
4. New protein vital for immune response is found in surprise location
5. Secrets to antibodys success against West Nile Virus surprise scientists
6. Genetic analysis of Asian elephants in India reveals some surprises
7. Fish species plays surprise role in aiding coral reef recovery
8. Worms produce surprise insight into human fever
9. Two studies on bee evolution reveal surprises
10. Genetic surprise confirms neglected 70-year-old evolutionary hypothesis
11. Vanishing beetle horns have surprise function
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: surprise about our body clock

(Date:12/22/2014)... , Dec. 22, 2014  NXT-ID, Inc. (NASDAQ: ... "Company"), a biometric authentication company focused on the growing ... entertainer and security consultant, Apollo Robbins for ... smart wallet.  Apollo Robbins ... 7 th , 2015, demonstrating some of his famous ...
(Date:12/19/2014)... 18, 2014  23andMe, Inc., the leading personal genetics ... pinpoints fine-scale differences in genetic ancestry of individuals from ... Since immigrants first arrived more than four hundred ... has served as a meeting place for peoples from ... the ongoing mixing of peoples with African, European, and ...
(Date:12/17/2014)... Valencell, a leader in performance biometric data ... industry leaders such as Intel, Jabra, Atlas, and Scosche ... products. These products will be showcased at CES 2015, ... . "Our partners choose PerformTek ... – with the clinical data to back it up," ...
Breaking Biology News(10 mins):NXT-ID Hires Master Pickpocket and Security Consultant Apollo Robbins for Wocket Smart Wallet CES 2015 Debut 2NXT-ID Hires Master Pickpocket and Security Consultant Apollo Robbins for Wocket Smart Wallet CES 2015 Debut 3NXT-ID Hires Master Pickpocket and Security Consultant Apollo Robbins for Wocket Smart Wallet CES 2015 Debut 423andMe Study Sketches Genetic Portrait of the United States 223andMe Study Sketches Genetic Portrait of the United States 323andMe Study Sketches Genetic Portrait of the United States 4Valencell PerformTek Biometrics Power the Most Accurate Wearables at CES 2015 2
... Vertebral fractures are a common cause of ... powerful predictors of future spine and hip fractures. ... simply fail to recognize vertebral fractures in their ... intervention is often not initiated. The Vertebral ...
... CHICAGO, IL (May 8, 2011) Research being ... individuals for hepatitis C based on age instead of ... well as prevent liver disease. Additionally, the rate of ... disease and type 2 diabetes is relatively low, and ...
... the Faculty of Medicine & Dentistry at the University ... kill neurons. This finding is significant because a specific ... medical community as a potential treatment for MS and ... post-doctoral fellow, Yohannes Haile, both from the Division of ...
Cached Biology News:New IOF teaching tool helps health professionals identify vertebral fractures 2Strides in identifying and improving screening practices and treatment for liver diseases 2Discovery demonstrates potential MS therapy could kill brain cells 2
(Date:12/24/2014)... Missouri (PRWEB) December 23, 2014 GMO ... Swiss biotechnology company, Syngenta, are in the process of ... proceedings. The consolidated case is In Re: Syngenta AG ... U.S. District Court for the District of Kansas. , ... has been handed over to U.S. District Judge John ...
(Date:12/24/2014)... December 23, 2014 The ... such as its definition, classification, application and ... specification, manufacturing process, and product cost structure. ... applications. The analysis also covers upstream raw ... industry development trend and proposals. In the ...
(Date:12/24/2014)... , Dec. 23, 2014 Vermillion, ... focused on gynecologic disease, announced today that investors ... , Birchview Fund LLC and several Vermillion directors ... unregistered shares of Vermillion,s common stock and warrants ... in a private placement.  Under ...
(Date:12/22/2014)... The Center for Professional Innovation ... training across the life sciences industry, has partnered with ... to provide the organization's members with discounted classroom courses, ... the more than 350 sessions across 80 course titles. ... when registering for a public course at ...
Breaking Biology Technology:Carey Danis & Lowe Reports on Syngenta GMO Corn Transfer Order 2Worldwide Methyl Mercaptan Market 2015-2020 Forecasts on Development & Trends Now Available at ReportsnReports.com 2Vermillion Announces Equity Financing of up to $18.9 Million; Suspends ATM Program 2Vermillion Announces Equity Financing of up to $18.9 Million; Suspends ATM Program 3Vermillion Announces Equity Financing of up to $18.9 Million; Suspends ATM Program 4Vermillion Announces Equity Financing of up to $18.9 Million; Suspends ATM Program 5CfPIE Announces Partnership with the Society for Clinical Data Management 2CfPIE Announces Partnership with the Society for Clinical Data Management 3
... Md., Oct. 12 Sequella, Inc., a clinical-stage ... treat life-threatening infectious diseases, today announced that it ... (SBIR) grant from the National Institutes of Health ... (NIAID) for the development of SQ641, Sequella,s lead ...
... Calif., Oct. 12 Raptor Pharmaceutical Corp. ("Raptor" or ... from the completed treatment phase of its open-label Phase ... in adolescent patients with non-alcoholic steatohepatitis ("NASH"), a progressive ... 5% of the U.S. population. At the completion of ...
... , ... singer, Cynthia Basinet petitions the United Nations Sixty-fourth General Assembly Fourth Committee on behalf ... ... and singer, Cynthia Basinet petitions the United Nations Sixty-fourth General Assembly Fourth Committee on ...
Cached Biology Technology:Sequella Obtains Funding to Continue Expansion of its Anti-infectives Pipeline 2Sequella Obtains Funding to Continue Expansion of its Anti-infectives Pipeline 3Raptor Pharmaceutical Reports Positive Interim Phase 2a Clinical Data in Non-Alcoholic Steatohepatitis (NASH) 2Raptor Pharmaceutical Reports Positive Interim Phase 2a Clinical Data in Non-Alcoholic Steatohepatitis (NASH) 3Raptor Pharmaceutical Reports Positive Interim Phase 2a Clinical Data in Non-Alcoholic Steatohepatitis (NASH) 4Raptor Pharmaceutical Reports Positive Interim Phase 2a Clinical Data in Non-Alcoholic Steatohepatitis (NASH) 5Raptor Pharmaceutical Reports Positive Interim Phase 2a Clinical Data in Non-Alcoholic Steatohepatitis (NASH) 6Actress and Singer, Cynthia Basinet Petitions United Nations 2
Mouse monoclonal antibody raised against a partial recombinant ST3GAL2. NCBI Entrez Gene ID = ST3GAL2...
... Apoptosis is an evolutionarily conserved form of ... process. The central component of this ... called caspases. These enzymes participate in ... in response to pro-apoptotic signals and result ...
... DNA Visualizer Extraction Kit is manufactured for ... DNA damage byexposure to UV light. The ... is often used for DNA-cloning work. The ... bromide and exposure of UV light damages ...
...
Biology Products: