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A new way of looking at molecular motors

one dynein while mammals have genes for more than 40 kinesins, 40 myosins and more than a dozen dyneins.

Genetic and acquired defects in the motors cause disease by preventing developing cells from migrating to their necessary destinations before birth or by preventing parts of the body, such as sperm tails or the tiny hairs that keep mucus flowing in the lungs, from moving when they are supposed to. The motors in parasitic organisms contribute to disease by enabling the parasites to break through biological barriers within the human body and actively invade cells.

So far, molecular motors have been found in all organisms but bacteria, red algae, and the parasite Giardia. The new myosin classification system should help cell biologists, biochemists, biophysicists, parasitologists, and medical researchers make advances in a wide variety of fields, from veterinary medicine to tropical diseases.


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Source:Howard Hughes Medical Institute


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