Navigation Links
A new tool against brain disease

autoimmunity," Walker noted. And while an ideal clinical strategy would be to seek to switch off PD-1 only in HIV-specific T cells, techniques for such a targeted approach do not exist, he said.

The researchers are also exploring PD-1 measurement as a diagnostic tool, said Walker. "Currently, we just count the number of helper T cells to decide when to treat someone, but we are excited about the possibility that adding PD-1 measurement might tell us more about the likelihood of progression of the disease and need for treatment in infected people," he said.

Walker said that scientists know little about the evolutionary purpose of a pathway that would deactivate such an important component of the immune system in the face of a viral attack. "It may be that in the heat of a battle that it sees it's not winning, the body makes an adjustment to try to co-exist," he said. "But we really do not know at this point."

Walker emphasized that the study could not have been done without his group's ongoing collaboration with the University of KwaZulu Natal. "These are studies that simply could not have been done in the United States," he said. "Despite the fact that these patients in Africa are living in poverty and in rural areas, it is easier for us to obtain their cooperation in such studies than with patients in the United States.

"It was with the key support of the Doris Duke Charitable Foundation and the Nelson Mandela School of Medicine that we have been able to build a biomedical research institute and develop this rich international collaboration that enables us to study the HIV epidemic at its epicenter, to gain knowledge that we could not obtain anywhere else," he said.
'"/>

Source:leesiegel@ucomm.utah.edu


Page: 1 2 3 4

Related biology news :

1. Enzyme, lost in most mammals, is shown to protect against UV-induced skin cancer
2. Bound for destruction: Ubiquitination protects against improper Notch signaling
3. Female sex hormones play a vital role in defense against sexually transmitted diseases
4. In the sea slugs defense against lobsters, confusion is key
5. Antibodies from plants protect against anthrax
6. Molecular models advance the fight against malaria
7. Sickle cell and protection against malaria
8. Live vaccines more effective against horse herpes virus
9. Turning viruses into allies against cancer
10. Friendly bacteria in humans may protect against HIV
11. NSAID drug protects against intestinal tumors in mice, despite poor diet and gene losses
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: new tool against brain disease

(Date:12/3/2009)The extinction of plant and animal species can be likened to emptying a museum of its collection, or dumping a cabinet full of potential medicines into the trash, or replacing every local cuisine with
(Date:12/3/2009)ALBUQUERQUE, N.M. Most scientists believe that staph infections are caused by many bacterial cells that signal each other to emit toxins. The signaling process is called quorum sensing because many b
(Date:12/3/2009)Forest dwellers must be included in the design of the upcoming forest deal at Copenhagen in order to avoid a humanitarian crisis, according to a scientist at the University of Leeds. , Writing today
Breaking Biology News(10 mins):Species down, disease up 2Species down, disease up 3Species down, disease up 4Stopping MRSA before it becomes dangerous is possible, Sandia/UNM researchers find 2Stopping MRSA before it becomes dangerous is possible, Sandia/UNM researchers find 3Forest deal at Copenhagen must avoid creating 'carbon refugees' 2Xanodyne Announces New President CEO and Completes 2438 Million Equity Financing 47880 1Xanodyne Announces New President CEO and Completes 2438 Million Equity Financing 47880 2In Both the U S and Mexico we Must Advance not Retreat From Strategic Government Goals Regarding Drug Addiction and Drug Related Crime Says Narcono 47878 1In Both the U S and Mexico we Must Advance not Retreat From Strategic Government Goals Regarding Drug Addiction and Drug Related Crime Says Narcono 47878 2Cardiogenesis Announces Presentation of its PHOENIX 28R 29 Combination TMR Plus Stem Cell Delivery System at the International Society of Minimally In 4536 1Cardiogenesis Announces Presentation of its PHOENIX 28R 29 Combination TMR Plus Stem Cell Delivery System at the International Society of Minimally In 4536 2Cardiogenesis Announces Presentation of its PHOENIX 28R 29 Combination TMR Plus Stem Cell Delivery System at the International Society of Minimally In 4536 3
...researchers have developed a computer modeling app... antibodies, molecules key to the immune system. T...body that will improve its effectiveness. , The ...rsion of cetuximab, a drug commonly used to treat ...0 times greater affinity than the original molecul...
... bioMETRX, Inc. (OTC,Bulletin Board: BMRX) a lead... today announced that it has acquired a patent tha...ecure portable locks. The company believes that t.... For many years, consumers have been using portab...to secure personal belongings in lockers,and stora...
..., Sept. 10 ,Communication Intelligence Corporation...lier of electronic signature solutions for busines... the recognized leader in biometric,signature veri...el Betts to,the CIC Board of Directors. Mr. Betts...and,financial services industries and holds the FL...
Other Biology News:MIT model could improve some drugs' effectiveness 2MIT model could improve some drugs' effectiveness 3bioMETRX, Inc. Acquires Patent for Biometric Padlock 2Michael A. Betts, Seasoned Financial Services Executive, Joins CIC Board of Directors 2Michael A. Betts, Seasoned Financial Services Executive, Joins CIC Board of Directors 3
(Date:12/4/2009)NEW YORK, Dec. 4 Stemline Therapeutics, Inc. today announced that data from pre-clinical studies of its IL-3R targeting agents, SL-401 and SL-501, in both in vitro and animal models of human chroni
(Date:12/3/2009)DALLAS, Dec. 3 ACCESS PHARMACEUTICALS, INC. (OTC Bulletin Board: ACCP), today provided an update on its European commercial launch of MuGard, an FDA approved treatment for oral mucositis, a deb
(Date:12/3/2009)WALTHAM, Mass., Dec. 3 Inverness Medical Innovations, Inc. (NYSE: IMA ), a global leader in enabling individuals to take charge of their health at home through the merger of rapid diagnostics and h
(Date:12/2/2009)MANILA, Philippines, Dec. 2 Spectrum Blue Steel is emerging as one of the fastest growing green energy companies on the planet. Through the efforts of True Green Energy Group and True Green Planet,s
Breaking Biology Technology:Stemline Therapeutics Announces Poster Presenting in vivo and Anti-Cancer Stem Cell Activity of SL-401 against Chronic Myeloid Leukemia (CML) at the 51st Annual Meeting of the American Society of Hematology (ASH) 2Access Pharmaceuticals Provides Update on MuGard Commercial Launch in Europe 2Access Pharmaceuticals Provides Update on MuGard Commercial Launch in Europe 3Access Pharmaceuticals Provides Update on MuGard Commercial Launch in Europe 4Spectrum Blue Steel partners with Famous Chemists for Procuring Profitable Applications from Garbage Using the Biosphere MKV and Electrostatic Precipitators 2Spectrum Blue Steel partners with Famous Chemists for Procuring Profitable Applications from Garbage Using the Biosphere MKV and Electrostatic Precipitators 3
... Madison, Wis. -- Two years ago, I signed a bud...e state,s history. And on Monday, I signed a budg... our state asked us to do three things with this b...priority, and freeze property taxes. I,m pleased ...ed up to our commitment to Wisconsin families. , ,...
...The Wisconsin Alumni Research Foundation has lic...Chemicon to commercialize research products using...ny Serologicals announced Tuesday. , ,Chemicon w...of stem cell technologies, which were developed an...dison . , ,Jeff Linton, president of Chemicon, sa...
... - Firstlogic, Inc ., a provider of enterprise i...that Crate and Barrel housewares retailer has de...anage the data quality in its new customer managem...stlogic,s software suite to achieve data quality i...nels where customer and product data flows.The sys...
Other Biology Technology:A budget that moves Wisconsin forward 2A budget that moves Wisconsin forward 3A budget that moves Wisconsin forward 4WARF signs stem cell agreement with California firm 2
... containing a clone of the human Topoisomerase II ... topological state of nucleic acids by passing an ...enerates a separate DNA helix (1,2) . As a result ...enzyme can relax negatively or positively supercoi...
...I catalyzes the template-directed polymerization o...DNA Polymerase I possesses a 3?5 exonuclease activ...rror rate during DNA replication, and also contain...zyme to replace nucleotides in the growing strand ...
...e Klenow Fragment is a genetically engineered Klen...vity has been removed, leaving only the 5 to 3 pol...ctivity makes Exo- Klenow Fragment the enzyme of c...s by the random primed method, and for DNA sequenc...
T7 RNA Polymerase from Invitrogen
Biology Products: