Navigation Links
A new link between stem cells and tumors

ng these molecules is disturbed."

Whether Prospero and its partners get to the right place depends on the activity of specific genes in the stem cell. EMBL PhD student Emmanuel Caussinus from Gonz�lez's group created neuroblasts in which these genes were disrupted. "We no longer had normal neuroblasts and daughter cells capable of becoming part of a nerve," Caussinus says. "Instead, we had a tumor."

When these altered cells were transplanted into flies, the results were swift and dramatic. The tissue containing the altered cells grew to 100 times its initial size; cells invaded other tissues, and death followed. The growing tumor became "immortal", Caussinus says; cells could be retransplanted into new hosts for years, generation after generation, with similar effects.

The study proves that specific genes in stem cells ?those which control the fates of daughter cells ?are crucial. If such genes are disrupted, the new cells may no longer be able to control their reproduction, and this could lead to cancer. "It puts the focus on the events that create asymmetrical collections of molecules inside stem cells," Gonz�lez says. "This suggests new lines of investigation into the relationship between stem cells and tumors in other model organisms and humans."


'"/>

Source:European Molecular Biology Laboratory


Page: 1 2

Related biology news :

1. Variation in womens X chromosomes may explain differences among individuals, between sexes
2. Edible bivalves as a source of human pathogens: signals between vibrios and the bivalve host.
3. Study reveals dramatic difference between breast cancers in US and Africa
4. Molecular fossils uncover link between viruses and the immune system
5. Research may provide new link between soft drinks and weight gain
6. A new molecule discovered in the battle between plants and disease
7. Underground tunnels discovered as means for communication between immune system cells
8. New discovery blurs distinction between human cells and those of bacteria
9. Plants discriminate between self and non self
10. Genetic link confirmed between Polynesians and indigenous Taiwanese
11. European Commission funds EBI to do new research on synergies between bioinformatics and medical informatics
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: new link between stem cells and tumors

(Date:5/23/2013)... Public Health at Emory University, along with partners ... a $4 million grant over four years to ... and Exposome Research Center: Understanding Lifetime Exposures). The ... in the United States. , The HERCULES ... Environmental Health Sciences (NIEHS) of the National Institutes ...
(Date:5/23/2013)... cancer patients unnecessarily undergo surgery or harsh treatments ... slow-growing and aggressive forms of the disease. Researchers ... Medical Institutes are developing technology that allows patients ... relatively mild treatments or take drastic measures. , ... an associate professor of biomedical engineering at Case ...
(Date:5/23/2013)... of the world,s largest and fastest growing open-access ... Frontiers in Bioengineering and Biotechnology . ... Frontiers in Bioengineering and Biotechnology will ... emerging bioengineering and biotechnology research to be disseminated ... and Biotechnology will provide an open-science and ...
Breaking Biology News(10 mins):Emory, Georgia Tech receive first human exposome center grant in US 2Emory, Georgia Tech receive first human exposome center grant in US 3Using big data to identify prostate cancers and best treatments 2Using big data to identify prostate cancers and best treatments 3Frontiers launches new open-access journal in Bioengineering and Biotechnology 2
... the Americas avoid competing for the same lunch, or ... from a new study by a pair of researchers ... shows that it,s not just chance that,s at play, ... force in the evolution of many carnivores, influencing such ...
... 10, 2009)The use of common and readily available screening ... scoring systemssuch as the Framingham Risk Scorehas the potential ... who are not originally thought to be at high ... Society of Interventional Radiology,s 34th Annual Scientific Meeting. About ...
... but scientists have found a Yellowstone National Park alga ... algae called Cyanidioschyzon -- thrives in extremely ... around hot springs, said Tim McDermott, professor in the ... State University. Cyanidioschyzon could someday help ...
Cached Biology News:American carnivores evolved to avoid each other, new study suggests 2Simple test helps predict heart attack risk 2Simple test helps predict heart attack risk 3Montana State team finds Yellowstone alga that detoxifies arsenic 2Montana State team finds Yellowstone alga that detoxifies arsenic 3
(Date:5/23/2013)... May 23, 2013 Virobay, Inc. today announced ... has reached an important milestone, as Virobay has now ... a selective cathepsin S inhibitor.   The ... randomized, placebo-controlled study designed to evaluate the safety, tolerability, ... healthy adults. "The initiation of this Phase ...
(Date:5/23/2013)... , May 23, 2013 Z Trim ... value-added ingredients to a variety of industries, announced that ... a panel discussion at this year,s National Restaurant Association ... 2013, on behalf of the Research Chefs Association.  Chef ... Restaurants: The Good, the Bad and the Ugly," joining ...
(Date:5/23/2013)... EASTON, Mass. , May 23, 2013 ... today announced that the Company will host a teleconference ... to provide a business update. The teleconference information is ... Time: 11:00 a.m. Eastern Daylight Time (EDT) ... ); (302) 607-2001 (Int,l) Passcode: VS22823 ...
(Date:5/23/2013)... BUSAN, South Korea , May 23, 2013 ... collaboration with SillaJen, Inc., a private biotherapeutics and ... of targeted biological products for cancer, announced today ... antibodies in patients treated with the oncolytic and ... This research was published in the ...
Breaking Biology Technology:Virobay, Inc. initiates a Phase 1 Trial of VBY-036, a compound intended for the treatment of neuropathic pain 2Virobay, Inc. initiates a Phase 1 Trial of VBY-036, a compound intended for the treatment of neuropathic pain 3Z Trim's Chef Erin Ryan sits on Expert Panel at NRA Show 2Z Trim's Chef Erin Ryan sits on Expert Panel at NRA Show 3Pressure BioSciences, Inc. to Discuss First Quarter 2013 Financial Results and Provide Business Update 2Pusan National University Announces Science Translational Medicine Publication Highlighting Landmark Demonstration of Functional Anti-Cancer Antibody Induction in Patients Following JX-594 Treatment 2Pusan National University Announces Science Translational Medicine Publication Highlighting Landmark Demonstration of Functional Anti-Cancer Antibody Induction in Patients Following JX-594 Treatment 3
... Partner with Biocareercenter.com ... Oct. 2 According to the National,Postdoc Association, more ... the United States today. With only 30 percent of,this ... emerging need to find more quality jobs in the ...
... Calhoun Credits Early Diagnosis with Saving his Life, ... 2007:,The MedTech Conference will highlight how everyday patients are ... as speakers on the,diversity and strength of the economic ... 1 through Oct. 3., Co-writing "A PASSION TO ...
... MISSISSAUGA, ON, Oct. 2 /PRNewswire-FirstCall/ - Vasogen Inc.,(NASDAQ: ... the research and,commercial development of technologies targeting the ... its,quarterly results after the close of the North ... conference call and audio web cast will also,be ...
Cached Biology Technology:Bio Career Center Launches First Online Jobs Board for Life Science PhDs, MDs 2U.S. Commerce Secretary Gutierrez to Address AdvaMed 2007 2U.S. Commerce Secretary Gutierrez to Address AdvaMed 2007 3Vasogen Announces Third Quarter Conference Call and Webcast of Bio InvestorForum 2007 Presentation 2Vasogen Announces Third Quarter Conference Call and Webcast of Bio InvestorForum 2007 Presentation 3Vasogen Announces Third Quarter Conference Call and Webcast of Bio InvestorForum 2007 Presentation 4
No description available in Ensembl Antigen: Recombinant Protein Epitope Signature Tag (PrEST)....
...
Normal Bovine Serum; U.S. sourced, ideal for those who seek an uncompromising quality. Low Hemoglobin levels; U.S. sourced, ideal for those who seek an uncompromising quality. Low Hemoglobin lev...
...
Biology Products: