ies include an expanded HIV vaccine candidate
pipeline, improvements in animal models, a growing database from
clinical trials, and the availability of new quantitative laboratory
tools that make comparisons among vaccine studies feasible." What is
needed, they argue, is a way of tying all of these opportunities
together, and their plan provides a model for doing just that.
"A preventive vaccine is the world's best long-term hope for bringing
the HIV/AIDS epidemic under control," said Helene Gayle, Director of
the Gates Foundation's HIV, TB, and Reproductive Health program and one
of the plan's authors. "We hope that that the Global HIV Vaccine
Enterprise will speed the development of a vaccine by bringing new
collaboration, resources, and strategic focus to the field."
"The partners in the Global HIV Vaccine Enterprise are committed to the
themes of cooperation, collaboration, and transparency in advancing HIV
vaccine research and development," said Anthony S. Fauci. "By working
together, we will greatly accelerate progress toward the critical goal
of developing a safe and effective HIV vaccine to help curb the global
HIV/AIDS pandemic."
"Being from the continent worst hit by the HIV/AIDS epidemic that has
claimed more than twenty million lives and wiped out decades of
development gains," said Pascoal Mocumbi, "I do believe that this
scientific strategic plan will not only accelerate the development of a
lifesaving HIV vaccine but also boost African capacity in health
research to address new health threats."
In a related commentary on the plan, David D. Ho, Scientific Director
of the Aaron Diamond AIDS Research Center at the Rockefeller University
in New York, said that "there is no doubt that this roadmap will be
regarded as a useful instrument to bring greater cohesion and
coordination to the field."
Ho urges the Enterprise not to ignore the important contributions made
by scientists outside of the collaboration. "It is my contention that
great new ideas are as l
'"/>Source:
PLoS Medicine
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