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A much-needed shot in the arm for HIV vaccine development

ies include an expanded HIV vaccine candidate pipeline, improvements in animal models, a growing database from clinical trials, and the availability of new quantitative laboratory tools that make comparisons among vaccine studies feasible." What is needed, they argue, is a way of tying all of these opportunities together, and their plan provides a model for doing just that. "A preventive vaccine is the world's best long-term hope for bringing the HIV/AIDS epidemic under control," said Helene Gayle, Director of the Gates Foundation's HIV, TB, and Reproductive Health program and one of the plan's authors. "We hope that that the Global HIV Vaccine Enterprise will speed the development of a vaccine by bringing new collaboration, resources, and strategic focus to the field." "The partners in the Global HIV Vaccine Enterprise are committed to the themes of cooperation, collaboration, and transparency in advancing HIV vaccine research and development," said Anthony S. Fauci. "By working together, we will greatly accelerate progress toward the critical goal of developing a safe and effective HIV vaccine to help curb the global HIV/AIDS pandemic." "Being from the continent worst hit by the HIV/AIDS epidemic that has claimed more than twenty million lives and wiped out decades of development gains," said Pascoal Mocumbi, "I do believe that this scientific strategic plan will not only accelerate the development of a lifesaving HIV vaccine but also boost African capacity in health research to address new health threats." In a related commentary on the plan, David D. Ho, Scientific Director of the Aaron Diamond AIDS Research Center at the Rockefeller University in New York, said that "there is no doubt that this roadmap will be regarded as a useful instrument to bring greater cohesion and coordination to the field." Ho urges the Enterprise not to ignore the important contributions made by scientists outside of the collaboration. "It is my contention that great new ideas are as l
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Source:PLoS Medicine


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