Navigation Links
A human parasite with a streamlined mitochondrion

Mitochondria, as they are defined in textbooks, are essential for eukaryotic cells--including our own--because they make large amounts of energy as they use oxygen. However, some eukaryotic cells, including important parasites of humans--such as Entamoeba histolytica, the causal agent of amoebic dysentery--live in environments that are too oxygen poor to support this process. Nevertheless, Entamoeba still contains a somewhat mysterious organelle, called a mitosome, that is evolutionarily derived from mitochondria. As reported by researchers this week, the mitosome can represent a surprisingly pared-down version of the much more sophisticated mitochondrion.

In their new work on the mitosome, a team led by Edmund Kunji at the MRC Dunn Unit, Jorge Tovar at the Royal Holloway University, and Martin Embley at the University of Newcastle upon Tyne provide intriguing clues to the function of this enigmatic organelle. They show that the mitosome contains a single type of a protein, called a mitochondrial carrier, that in human mitochondria exists in many different specialized versions. In humans, these diverse carriers are needed to import and export the varied chemicals required, or produced, by our complex mitochondria. The presence of a single carrier in the Entamoeba mitosome means that it must be able to do far fewer jobs than our own mitochondria. Further experiments performed by the team reveal that the Entamoeba carrier can only transport ADP and ATP, suggesting that it could fuel energy-requiring reactions within the mitosome but might not perform other functions. The work suggests that the Entamoeba mitosome may represent the simplest mitochondrion yet described, and thus it provides a model system for probing which mitochondrial functions are truly essential for eukaryotic cells.


'"/>

Source:Cell Press


Page: 1

Related biology news :

1. Novel technology detects human DNA mutations
2. Current human embryonic stem cell lines contaminated UCSD/Salk team finds
3. UWs Rosetta software to unlock secrets of many human proteins
4. Genome-wide mouse study yields link to human leukemia
5. Found: Missing sequence of the human Y chromosome
6. Study finds more than one-third of human genome regulated by RNA
7. Molecular machine may lead to new drugs to combat human diseases
8. Sea skate experiment sheds light on human cell transport
9. Mouse brain tumors mimic those in human genetic disorder
10. Zebrafish may hold key to understanding human nerve cell development
11. Yale researchers identify molecule for detecting parasitic infection in humans
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: human parasite with streamlined mitochondrion

(Date:7/24/2014)... Invertebrate numbers have decreased by 45% on average over ... doubled, reports a study on the impact of humans ... the enormous benefits invertebrates such as insects, spiders, crustaceans, ... pollination and pest control for crops, decomposition for nutrient ... published in Science and led by UCL, ...
(Date:7/24/2014)... Imagine a smog-free Los Angeles, where electric cars ply ... run on heat from beneath the earth, from howling ... new Stanford study finds that it is technically and ... one powered by clean, renewable energy. Published in ... sustainable, inexpensive and reliable energy supply in California that ...
(Date:7/24/2014)... has its own microbial terroir, meaning the microbial populations ... in the product, creating the final flavor according to ... Applied and Environmental Microbiology . This is the first ... sake brewery. , Many sake makers inoculate with ... Mills of the University of California, Davis, but he ...
Breaking Biology News(10 mins):Invertebrate numbers nearly halve as human population doubles 2Invertebrate numbers nearly halve as human population doubles 3Stanford study shows how to power California with wind, water and sun 2Stanford study shows how to power California with wind, water and sun 3Stanford study shows how to power California with wind, water and sun 4The microbes make the sake brewery 2
... found that winter precipitation such as rain and snow ... 100 years. Similar increases in heavy rainfall have now ... autumn. A previously reported reduction in heavy summer rainfall ... the last decade indicating a return to more typical amounts ...
... in Civil and Environmental Engineering at MIT reveal that ... lies in the specific geometric configuration of structural proteins, ... work cooperatively to resist force and dissipate energy. ... as steel, even though the glue of hydrogen bonds ...
... change, stem cell researchScientists are frequently called upon ... that pervade the daily news headlines, yet most ... of the television studio or leading questions from ... American Institute of Biological Sciences (AIBS), "Communicating Science: ...
Cached Biology News:Heavy rainfall on the increase 2Protein's strength lies in h-bond cooperation 2Protein's strength lies in h-bond cooperation 3Priming scientists for successful media interviews 2
(Date:7/25/2014)... "Ischemic Stroke and Cerebral Stroke Global ... the Ischemic Stroke and Cerebral Stroke clinical trial ... relating to the clinical trials on Ischemic Stroke ... Stroke Research Report 2014 at: http://www.marketresearchreports.biz/analysis/213207 ... numbers and their recruitment status as per the ...
(Date:7/25/2014)... -- Research and Markets  has announced the ... report to their offering. ... Metabonomics is the scientific study of chemical processes ... technique that is being widely used in biology, ... molecules that are present in blood, urine, and ...
(Date:7/25/2014)... California (PRWEB) July 25, 2014 Lawrence ... named to Thomson Reuters list of " The World's ... are part of the 3,000 researchers who were identified ... to recognize those who published the highest-impact work (2002-2012 ... research papers on combustion modeling . , "This ...
(Date:7/25/2014)... Sinovac Biotech Ltd. (Nasdaq: SVA ), a leading ... today announced that it will release its unaudited financial results ... close on Thursday, August 14, 2014 EDT. The Company will ... Friday, August 15, 2014, at 8:00 a.m. EDT (Friday, August ... the Company,s financial results and provide an update on recent ...
Breaking Biology Technology:Ischemic Stroke and Cerebral Stroke Global Clinical Trials Review H2, 2014: MarketResearchReports.Biz 2Ischemic Stroke and Cerebral Stroke Global Clinical Trials Review H2, 2014: MarketResearchReports.Biz 3Global Metabolomics Market 2014-2018: Key Vendors are Agilent, Bio-Rad, Bruker, Human Metabolome and Metabolon 2Scientists Burst onto Influential List for Combustion Research 2Scientists Burst onto Influential List for Combustion Research 3Scientists Burst onto Influential List for Combustion Research 4Sinovac to Host Conference Call to Report Second Quarter 2014 Unaudited Financial Results 2
... rapidly emerging advanced biofuels industry urged congressional leaders today ... the commercialization of new biofuel production technologies. ... Members of the House Ways and Means and Senate ... pressed for a five year extension of the Cellulosic ...
... Corp. (NASDAQ: BSTC ), a biopharmaceutical company ... in the U.S. and XIAPEX® in Europe and Eurasia, ... at the following upcoming investor conferences during the month ... Company 32nd Annual Health Care Conference (Boston, MA) ...
... Institute for Biologically Inspired Engineering at Harvard University and ... magnetic sensitivity in an organism that is not naturally ... magnetize a variety of different cell types in medical, ... today,s issue of PLoS Biology . Magnetic ...
Cached Biology Technology:Global Leaders in Advanced Biofuels Industry Urge Congressional Leaders to Extend Critical Tax Provisions 2BioSpecifics Technologies Corp. Announces Presentations at Two Upcoming Investor Conferences in March 2New 'magnetic yeast' marks step toward harnessing Nature's magnetic capabilities 2New 'magnetic yeast' marks step toward harnessing Nature's magnetic capabilities 3
... Plasma Immunodepletion Kit specifically removes 20 of ... or serum in preparation for further proteomics ... the plasma proteome whether you use one- ... or go straight to mass spectrometry. This ...
... a direct antibiotic-based selection ... Recombinant selection depends solely ... the need for costly ... and inexpensive process provides ...
... can perform many sophisticated DNA analysis and protein ... than just another sequence analysis product. Imagine having ... analyses to be performed each time you have ... sheets which specify exactly how your output will ...
... is the first fully automated proteomics workcell. ... operations with complete data tracking. It automates ... picking through final protein expression and measurement. ... delivering a plate to any of its ...
Biology Products: