Navigation Links
A first -- Hebrew University scientist observes brain cell development in 'real time'

For the first time anywhere, a researcher at the Hebrew University of Jerusalem has succeeded in observing in vivo the generation of neurons in the brain of a mammal.

Dr. Adi Mizrahi of the Department of Neurobiology at the Alexander Silberman Institute of Life Sciences at the Hebrew University, used mouse models to study how neurons, or nerve cells, develop from an undifferentiated cellular sphere into a rich and complex cell. This has great significance for the future of brain research, said Dr. Mizrahi, since "the structural and functional complexity of nerve cells remains one of the biggest mysteries of neuroscience, and we now have a model to study this complexity directly."

The results of Dr. Mizrahi’s groundbreaking work appeared in the online edition of Nature Neuroscience.

Using special microscopic imaging techniques, combined with virus gene technology, Dr. Mizrahi was able to develop an experimental model to study development of neural dendrites in vivo. The dendrites are the string-like extensions of the neuron that spread out to reach other neurons and serve as the points of communication between the neurons.

The model employed by Dr. Mizrahi in his research was the newborn neuron population which develops into the olfactory bulb of adult mice, providing them with a sense of smell. The development and maintenance of newborn neurons in this area was assessed by time-lapse imaging over several days at different stages of development. Mizrahi revealed that dendritic formation is highly dynamic. Moreover, once incorporated into the network, adult-born neurons in the study also remained dynamic and capable of continuous change.

This method provides a mechanism for observing, for the first time in a mammal, how a neuron develops into a rich and complex cell and how, once developed, neurons are maintained in the highly active and changing environment of the brain.

As for further research that som e day could lead to significant breakthroughs in treatment of neural disorders, Dr. Mizrahi noted that "there are only a few small areas in the brain which are capable of neurogenesis, and they hide secrets we want to reveal."
'"/>

Source:The Hebrew University of Jerusalem


Related biology news :

1. A genes first kiss sets off that affair known as puberty
2. Love at first smell
3. Worlds largest rainforest drying experiment completes first phase
4. PCRM develops worlds first cruelty-free insulin assay
5. Expression Project for Oncology (expO) completes first phase of standardized gene expression analyses
6. World-first Living Donor Islet Cell Transplant A Success; Procedure Offers Promise For Diabetics
7. DuPonts first biologically derived polymer receives global recognition
8. Anti cancer virotherapy well tolerated in first human administration, research finds
9. Unlike other mammals, newborn dolphins and orcas stay active 24/7 during first months of development
10. The first impact factor for PLoS Biology ?13.9
11. Moffitt-USF head toward first human trials of anti-cancer drug that targets protein AKT

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/21/2016)... 22, 2016 Unique technology ... for superior security   Xura, ... of secure digital communications services, today announced it is ... offer enterprise customers, particularly those in the Financial Services ... voice authentication within a mobile app, alongside, and in ...
(Date:3/15/2016)... 15, 2016 Yissum Research Development Company ... company of the Hebrew University, announced today the formation ... technology of various human biological indicators. Neteera Technologies has ... from private investors. ... detection of electromagnetic emissions from sweat ducts, enables reliable ...
(Date:3/11/2016)... , March 11, 2016 ... new market research report "Image Recognition Market by Technology ... (Marketing and Advertising), by Deployment Type (On-Premises and Cloud), ... To 2022", published by MarketsandMarkets, the global market is ... to USD 29.98 Billion by 2020, at a CAGR ...
Breaking Biology News(10 mins):
(Date:5/3/2016)... May 3, 2016  Dr. Thomas P. McHugh ... The Woodlands, Texas , now offers ... of treated fat cells in just 25-minutes, leaving a ... 90 percent of Americans report feeling bothered by excess ... reduction procedures are a growing industry. This innovative new ...
(Date:5/2/2016)... , May 2, 2016 ... that its technology partner Mannin Research Inc. will be ... (ARVO), which takes place from May 1-5, 2016 in ... will be meeting with its vendors and research partners. ... business development goals and other collaborative opportunities for the ...
(Date:5/2/2016)... ... May 02, 2016 , ... F.E.E.D. Co., the Feline ... their revolutionary, veterinarian-designed product for indoor cats. The NoBowl Feeding System replaces the ... food the way nature intended. NoBowls make cats happy and healthy. , Since ...
(Date:4/29/2016)... ... April 29, 2016 , ... Amendia, ... spinal surgical procedures, today announced the completion of a significant transaction and partnership ... and future customers and partners. Kohlberg & Company, L.L.C. (“Kohlberg”), a leading ...
Breaking Biology Technology: