Navigation Links
A case of mistaken molecular identity

protein, reacts with antibodies produced by Chagas patients.

"We showed that the same antibodies that attack heart cells can also interfere with rhodopsin," Levin said. "This is important, because it enlarges the concept of molecular mimicry in Chagas disease." Rhodopsin and beta1-adrenergic receptors in heart cells belong to the same class of molecules, a subfamily of the G-protein-coupled receptors, he pointed out.

Paveto, an independent researcher at INGEBI--an institute that is home to three HHMI international research scholars--conducted much of the painstaking work on the project by developing an original method to test rhodopsin function, said Levin.

Levin said that Chagas patients' vision problems are caused exclusively by the antibodies that block rhodopsin, and not by inflammation. "In the hearts of Chagas patients, we see scarring because there is a complex reaction that causes inflammation," he said. "But there are no such scars in the eyes of Chagas patients with reduced vision."

"No one knew about the night blindness, so we don't know, for instance, if Chagas patients have more accidents at night," Levin added. "That's one of many ideas to explore now. The research also points out that we need new drugs or vaccines to stop the parasite, and at a social level, it stresses the need to improve living conditions of Chagas patients, particularly those living in rural areas."


'"/>

Source:Howard Hughes Medical Institute


Page: 1 2 3

Related biology news :

1. A case of mistaken identity for the ivory-billed woodpecker?
2. Scientists ID molecular switch in liver that triggers harmful effects of saturated and trans fats
3. Source of molecular triggers in cutaneous T cell lymphoma identified
4. Plants, animals share molecular growth mechanisms
5. NYU researchers simulate molecular biological clock
6. Scientists reveal molecular secrets of the malaria parasite
7. Scientists identify molecular events that drive cell senescence
8. Researchers discover molecular mechanism that desensitizes us to cold
9. Findings have implications for tracking disease, drugs at the molecular level
10. Successful Test Of Single Molecule Switch Opens The Door To Biomolecular Electronics
11. At the molecular level, the predator is the prey
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: case mistaken molecular identity

(Date:2/5/2015)... 26, 2015 NXT-ID, Inc. (NASDAQ: NXTD ... authentication company focused on the growing mobile commerce market, ... http://www.nxt-id.com/ ) as part of its 2015 marketing and ... launched its new consumer website for Wocketwallet.com earlier this ... of NXT-ID said, "Our new corporate website naturally showcases ...
(Date:2/5/2015)... 28, 2015 Research and Markets ... the "Global Biometrics Market (2014-2020): Market Forecast ... report to their offering. , ... is anticipated to overtake ... increasing government spending towards IT security, government biometric ...
(Date:1/22/2015)... 2015 Valid S.A. ("Company") (BM&FBOVESPA: VLID3 ON), is pleased ... State of Washington,s Department of Licensing, ... and central issuance system for driver,s licenses and identification cards ... planning and development will start in January 2015, with enrollment ...
Breaking Biology News(10 mins):NXT-ID, Inc. Launches New Corporate Website As Part Of Ongoing 2015 Branding Initiatives For Wocket Smart Wallet 2NXT-ID, Inc. Launches New Corporate Website As Part Of Ongoing 2015 Branding Initiatives For Wocket Smart Wallet 3Global Biometrics Market (2014-2020): Market Forecast By Technologies, Applications, End Use, Regions and Countries 2Global Biometrics Market (2014-2020): Market Forecast By Technologies, Applications, End Use, Regions and Countries 3Valid USA Signs Contract For Washington Driver's License Issuance 2
... even those caused by antibiotic-sensitive bacteria, resist treatment. This ... impossible to cure. A key cause of this ... Starved bacteria resist killing by nearly every type of ... What produces starvation-induced antibiotic resistance, and how ...
... While shorter days and colder weather move many ... spent their summers in fieldwork are more likely to ... samples and crunching data from their summer,s labors. ... spent a month last summer in Mexico,s Sea of ...
... Although scientists have known for centuries that many bacteria produce ... toxic by-product of cellular activity. Now, researchers at NYU ... major role in protecting bacteria from the effects of numerous ... Nudler, PhD, the Julie Wilson Anderson Professor of Biochemistry at ...
Cached Biology News:What bacteria don't know can hurt them 2What bacteria don't know can hurt them 3Squid mystery in Mexican waters unraveled by Stanford biologist and a class of students 2Squid mystery in Mexican waters unraveled by Stanford biologist and a class of students 3Squid mystery in Mexican waters unraveled by Stanford biologist and a class of students 4Targeting bacterial gas defenses allow for increased efficacy of numerous antibiotics 2
(Date:2/27/2015)... Halifax, Nova Scotia (PRWEB) February 27, 2015 ... has been made aware of a fraudulent press release ... GlobeNewswire, purporting to be from Immunovaccine. This press release ... with Gilead Science, Inc. The press release did ... to the information contained within the press release. ...
(Date:2/27/2015)... Mass. , Feb. 27, 2015 ... of the NCATS rare-diseases portfolio " in ... a new financing technique to reduce the risk ... diseases and potentially unlock new levels of funding ... The product of a unique collaboration between scientists ...
(Date:2/27/2015)... 27, 2015 The fully automated ... UC) can sequentially analyze up to 48 samples ... high-sensitivity detection of targets by mass spectrometry. ... fulfill the measurement requirements of a wide range ... drug delivery and search for disease biomarkers, additives ...
(Date:2/27/2015)... FamilyFarms Group is pleased to announce its valued ... received the 2015 Tomorrow’s Top Producer Horizon Award. The ... 35, who has demonstrated excellence in the business of ... Tomorrow's Top Producer Horizon Award. Every year I look ... and learning from their experiences. It is truly humbling ...
Breaking Biology Technology:Immunovaccine Disclaims Hoax Press Release 2New Financing Technique May Hold Key to Unlocking Funding for Rare Diseases 2New Financing Technique May Hold Key to Unlocking Funding for Rare Diseases 3New Financing Technique May Hold Key to Unlocking Funding for Rare Diseases 4Shimadzu Corporation Launches Nexera UC - The World’s Foremost Unified Chromatography System 2Shimadzu Corporation Launches Nexera UC - The World’s Foremost Unified Chromatography System 3Matt Sims Receives the 2015 Tomorrow’s Top Producer Horizon Award 2
... years of cumulative expertise ... ... Tobira,Therapeutics Inc., a clinical stage biotechnology company committed to the,research and product ... company,s,senior management team. Tobira Therapeutics has been led since its,inception in 2006 ...
... Today at 1:00 pm ET / 10:00 am ... Anesiva,Inc. (Nasdaq: ANSV ) today announced ... (lidocaine hydrochloride monohydrate) powder,intradermal injection system. Zingo is ... associated with peripheral,intravenous (IV) line placements and blood ...
... June 30 ADVENTRX Pharmaceuticals,Inc. (Amex: ANX ... with,Theragenex, LLC and its Chairman and President and ... the Company has received,in full. The parties have ... action and all related claims and counterclaims, with,prejudice. ...
Cached Biology Technology:Tobira Therapeutics Inc. Announces Senior Management Team 2Tobira Therapeutics Inc. Announces Senior Management Team 3Anesiva Launches Needle-Free Zingo(TM) to Reduce Pain from IV Starts and Blood Draws in Children 2Anesiva Launches Needle-Free Zingo(TM) to Reduce Pain from IV Starts and Blood Draws in Children 3Anesiva Launches Needle-Free Zingo(TM) to Reduce Pain from IV Starts and Blood Draws in Children 4Anesiva Launches Needle-Free Zingo(TM) to Reduce Pain from IV Starts and Blood Draws in Children 5ADVENTRX Settles Dispute With Former Licensee 2
... aptamer screening and binding optimization and built ... on-chip synthesis platform. These microarrays are available ... Microarray Service. Probe Content ... than 1500 known aptamer sequences. Add up ...
... provides a comprehensive service for custom ... peptide microarrays synthesized on Paraflo microfluidic ... proteins/antibodies or serum samples. This comprehensive ... designs, binding assays using sample(s) provided ...
... Sciences provides a comprehensive epitope analysis ... synthesized on Paraflo microfluidic chips for ... development. This comprehensive service includes assistance ... using sample(s) provided by you, single ...
... Microarrays designed for RNA aptamer screening ... flexible and powerful Paraflo microfluidic on-chip synthesis ... can be synthesized on-chip and LC Sciences ... These microarrays are available as part of ...
Biology Products: