Navigation Links
A New Era of Hope for the World's Most Neglected Diseases

International health agencies have designated a group of 13 tropical infections as neglected diseases (Kala-azar (leishmaniasis), African Sleeping Sickness (African trypanosomiasis), Chagas Disease (American trypanosomiasis), Schistosomiasis, Lymphatic Filariasis (elephantiasis), Onchocerciasis (river blindness), Drancunculiasis (guinea worm), Soil-transmitted Helminthiases, Leprosy, Buruli Ulcer, Trachoma).

These diseases have much in common: they affect the world's poorest people (and are a cause of poverty); they are disabling, disfiguring, and stigmatizing; there is a shortage of safe and effective treatments; and affected patients have represented the lowest-priority markets for Western pharmaceutical manufacturers. Bernard Pécoul of the Drugs for Neglected Diseases Initiative (DNDi) has called these patients “the forgotten people.?/p>

The conventional wisdom is that the outlook for such patients is hopeless. As one of us has argued, “[They] have no purchasing power, no vocal advocacy group is pleading for their needs, and no strategic interests—military or security—are driving concern about these conditions?(BMJ 325: 176?77). Hence, only 13 new drugs have been developed for neglected tropical diseases since 1975, and they have garnered little international attention compared with “the big three?global health threats: HIV/AIDS, tuberculosis, and malaria.

Fortunately, there is good news to report. The ?005 reality,?argues Mary Moran of the London School of Economics in an article in PLoS Medicine (DOI: 10.1371/journal.pmed.0020302), is that an explosion of public–private partnerships for health has dramatically altered the landscape of neglected-disease drug development. Her analysis shatters a common illusion—that industry is profoundly disinterested in developing drugs for neglected diseases. “Long-held beliefs on neglected-disease drug development activity are no longer accurate,?writes Moran.

According to her analysis, 63 neglected
'"/>

Source:PLoS Medecine


Page: 1 2 3

Related biology news :

1. Worlds largest rainforest drying experiment completes first phase
2. Worlds pledge to halve hunger by 2015 looks like empty promise
3. Worlds smallest cancer detection device
4. Worlds largest flower evolved from family of much tinier blooms
5. Worlds leading scientists announce creation of Encyclopedia of Life
6. A New Era Of Hope For Neglected Diseases
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: New Era Hope for the World Most Neglected Diseases

(Date:11/21/2014)... Nov. 20, 2014 C-Labs LLC, a leading ... of Things (IoT), today announced the appointment of ... officer. Previously a strategic advisor to the firm, Mr. ... Mr. Traynor is based out of the C-Labs office ... to Chris Muench , Chief Executive Officer. ...
(Date:11/18/2014)... Nov. 18, 2014  The Secure Identity & ... today jointly announce the formation of The Airport ... its Identity and Biometric Entry and Exit ... received official support from BORDERPOL, the international non-profit ... and provide expertise regarding border security, traveler and ...
(Date:11/18/2014)... 17, 2014 The Parenteral Drug Association (PDA) today ... will speak and at least seven more will participate in ... Omni Shoreham Hotel in Washington D.C. , ... have significant support from the regulatory agencies in ... in our effort to help advance the use of ...
Breaking Biology News(10 mins):C-Labs Names Former Microsoft and Bsquare Executive as Chief Operating Officer 2Identity Management, Document Authentication and Biometric Companies Form "The Airport Entry and Exit Working Group", Releasing the Framework to Help Guide the Department of Homeland Security and Congress Towards Solutions 2Identity Management, Document Authentication and Biometric Companies Form "The Airport Entry and Exit Working Group", Releasing the Framework to Help Guide the Department of Homeland Security and Congress Towards Solutions 3FDA's Janet Woodcock, EMA's Emer Cooke Headline PDA Quality Metrics Conference 2
... half the size of a pencil eraser tells you when to ... go to sleep. The same cells also cause you to be ... circadian clock, comprised of about 20,000 time-keeping cells, has mystified scientists ... Now, a researcher at the University of Calgary is getting a ...
... have been indoctrinated into believing that our senses, ... communication network of brain cells, or neurons, each ... a neurotransmitter. Either neurons release a neurotransmitter that ... discharge and enhancing brain activity, or they dispatch ...
... phage, a primitive class of virus that infects bacteria ... have gained insight into the driving force behind this ... the past to occur through the release of pressure ... phages (also known as bacteriophages) are formed of a ...
Cached Biology News:The circadian clock: Understanding nature's timepiece 2Researchers make surprise discovery that some neurons can transmit three signals at once 2Researchers make surprise discovery that some neurons can transmit three signals at once 3Basis for DNA ejection from single phage particles 2
(Date:11/18/2014)... Sarasota, FL (PRWEB) November 17, 2014 ... novel point-of-care diagnostic tests – today announces its ... Control and Prevention’s (CDC) Get Smart About Antibiotics ... Antibiotics Week is a national campaign designed to ... local health departments, and non-profit and for-profit partners ...
(Date:11/18/2014)... November 17, 2014 Athena Signature Series: Turning ... Dr. Beverly Emerson, a professor in the Regulatory Biology Laboratory ... most recent discovery points to an “off switch” for drug ... and how her local research is making a global impact ... findings and then join host Cheryl K. Goodman, CEO of ...
(Date:11/18/2014)... 18, 2014 Brothers Josh and Bryce ... of PAWSitively Curing Cancer, Inc . in recognition ... (3) non-profit organization is dedicated to raising funds for ... to the University of Florida College of Veterinary ... Curing Cancer as the recipient of this vital funding. ...
(Date:11/18/2014)... Nov. 18, 2014 PDL BioPharma, Inc. (PDL) ... connection with the acquisition of Durata Therapeutics, Inc. by ... with the termination of PDL,s credit agreement with Durata, ... of $40 million, accrued interest, and prepayment and change ... a structured financing transaction with Durata in which PDL ...
Breaking Biology Technology:RPS Again Partners with the CDC in Support of the 2014 Get Smart About Antibiotics Week 2RPS Again Partners with the CDC in Support of the 2014 Get Smart About Antibiotics Week 3PAWSitively Curing Cancer, Inc. Launched By Two Children for National Pet Cancer Awareness Month 2PAWSitively Curing Cancer, Inc. Launched By Two Children for National Pet Cancer Awareness Month 3PDL BioPharma Announces Successful Conclusion of Debt Financing Agreement with Durata Therapeutics 2
... developer to describe a Web site, youre likely to learn about ... youre likely to learn a lot about pinball. , ,A pinball ... works not the mechanical side of working that involves ASP, ... attracts and retains customers. By thinking of the Internet as a ...
... putting their state into further debt to fund ... California voters approved Proposition 71, which will provide ... decade. , ,The proposition, which was endorsed by ... California Institute for Regenerative Medicine. The institute will ...
... labs at the research park. An investment of $8.5 ... niche-market biotech company to Wisconsin, where it will inhabit brand-new ... ,The company is targeting a type of debilitating genetic disease ... new technique. , , Symbiontics, Inc. , which drew about ...
Cached Biology Technology:My 50 cents: Web sites and pinball machines 2My 50 cents: Web sites and pinball machines 3My 50 cents: Web sites and pinball machines 4Californians: Stem cells important enough to go into debt for 2Wisconsin VCs draw Missouri biotech firm to state 2Wisconsin VCs draw Missouri biotech firm to state 3Wisconsin VCs draw Missouri biotech firm to state 4
JAB1 Immunogen: Synthetic peptide, conjugated to KLH, corresponding to residues S(201) E Y Q T I P L N K I E D F G V(216) of human JAB1. The sequence is identical in mouse and rat. Storage: -...
Blank Calibration Particles, 3.0-3.4 mu m 5 ml...
Alexa Fluor 647 anti-mouse IL-12 (Interleukin-12) / IL-23 (Interleukin-23) p40 25 ug...
MAb to Transferrin Dry Ice: No Preservative: NaN3 Availability When Not in Inventory: 14-21 Business Days...
Biology Products: