Navigation Links
15 generations of untrained jocks, couch potatoes show big physiological adaptations

ll from UCSD's Department of Medicine, Division of Physiology.

They are presenting their research at the 35th Congress of the International Union of Physiological Sciences in San Diego, March 31 - April 5, 2005. (See below * for specifics.)

Howlett continued: "However, we found that in addition the G15 'athletic' rats had increased performance due to central changes in oxygen delivery." Specifically, the running rats had improved cardiovascular systems (proportionally larger hearts (16% ) and increased blood flow (33%), reported in Kirkton et al., below) and respiratory systems (proportionally larger lungs (17%) and better oxygen diffusing capacity, reported in Giuliano et al., below) over the G7 stage, the researchers pointed out.

Oxygen delivery system maximized over time; support for 'controversial thesis'

Overall, Kirkton said the G15 results are exciting because "they clearly demonstrate that steps in the oxygen delivery system are coordinated to maximize efficiency, independent of exercise or other environmental influences." And by the G15 stage, the central delivery components (lung and cardiovascular system) have improved to better meet the demands of the muscles. "Additionally, our results provide support for the controversial hypothesis that suggests that physiological systems, such as the oxygen delivery pathway, are, over time, optimized in animals," Kirkton noted.

Next steps and implications for human attitudes and therapies

Having demonstrated the genetic role in endurance performance and the oxygen delivery systems, the group of researchers are turning their attention to identify the various genes involved that provide the underlying signal for "why" some subjects become more athletic, while others are couch potatoes.

This effort will include looking for genes and/or signaling mechanisms that prompt the initial signal for the differential abilities to run on a treadmill without training, as well
'"/>

Source:American Physiological Society


Page: 1 2 3

Related biology news :

1. Chimpanzees can transmit cultural behavior to multiple generations
2. Low levels of neurotransmitter serotonin may perpetuate child abuse across generations
3. Prototype just-in-time medical device enables untrained bystanders to save lives
4. Finding rewrites the evolutionary history of the origin of potatoes
5. Lance Armstrong through a physiological lens: hard training boosts muscle power 8%
Post Your Comments:
(Date:12/16/2009)... molecules form an intricate network of interactions. Today,s ... individual molecular reactions outside the cells. Since molecular ... the laboratory, scientists suspect that the kinetics of ... external probes. We expected the cellular reaction speed ... Braun. "However, our novel optical approach showed that ...
(Date:12/16/2009)... A University of Maryland School of Medicine researcher will ... nation,s most prominent scientists in the field of stem ... and Preventive Medicine, was chosen by the National Heart, ... of this consortium of national experts, which will be ... center will be funded by a $30 million grant ...
(Date:12/16/2009)... Dec. 3 BIO-key International, Inc. ... wireless public safety and finger-based biometric identification ... shareholders at a Special Shareholder Meeting held ... Law Enforcement Division to Interact911 Mobile Systems ... cast in favor and 1.2% were opposed. ...
Breaking Biology News(10 mins):Looking for the heartbeat of cellular networks 2University of Maryland School of Medicine receives $30 million to coordinate stem cell consortium 2University of Maryland School of Medicine receives $30 million to coordinate stem cell consortium 3BIO-key(R) Shareholders Overwhelmingly Approve Sale of Law Enforcement Division 2BIO-key(R) Shareholders Overwhelmingly Approve Sale of Law Enforcement Division 3Genomic Health to Present at Piper Jaffray Health Care Conference 14955 1Genomic Health to Present at Piper Jaffray Health Care Conference 14955 2Visage Imaging Introduces Visage 28R 29 7 for Windows and Mac OS X 6500 1Visage Imaging Introduces Visage 28R 29 7 for Windows and Mac OS X 6500 2Keryx Biopharmaceuticals to Present at the Piper Jaffray 21st Annual Health Care Conference 6495 1Keryx Biopharmaceuticals to Present at the Piper Jaffray 21st Annual Health Care Conference 6495 2
... Universitys Molecular Biosensor and Imaging Center have developed ... a key component of novel molecular biosensor technology ... can be used to monitor biological activities of ... in real time, are described in the February ...
... Southern Ocean, large quantities of surface-drifting plankton algae are able ... waters, which can affect the global carbon dioxide cycle. This ... has just drawn to a close in Cape Town on ... Institute, part of the Helmholtz Association. On February 5, an ...
... expedition of the Integrated Ocean Drilling Programs Nankai ... off the Kii Peninsula today. The expedition science ... on Dec. 19, 2007, aboard the drilling vessel ... physical characteristics of the Nankai Trough fault zone. ...
Other Biology News:Carnegie Mellon scientists develop fluorescent proteins for live cell imaging, biosensor design 2Carnegie Mellon scientists develop fluorescent proteins for live cell imaging, biosensor design 3Antarctic expedition provides new insights into the role of the Southern Ocean for global climate 2Antarctic expedition provides new insights into the role of the Southern Ocean for global climate 3Antarctic expedition provides new insights into the role of the Southern Ocean for global climate 4Scientists obtain core samples from subsea fault system off Japan 2
(Date:12/16/2009)... /PRNewswire/ -- Capitalizing on the continued ... an active venture capital market, leaders from BioCrossroads, ... Fund, Indiana University, Purdue University, the University of ... Suisse today announced the establishment of the INext ... funds. ,, Organized through BioCrossroads, Indiana,s initiative to ...
(Date:12/16/2009)... Dec. 16 Sequenom, Inc. (Nasdaq: ... Kenneth Buechler and Mr. David Pendarvis to its ... http://www.newscom.com/cgi-bin/prnh/20040415/SQNMLOGO ) ,, Kenneth F. Buechler, Ph.D., was ... Incorporated. From 1988 to 1994, Dr. Buechler was ... Dr. Buechler was a senior research scientist for ...
(Date:12/16/2009)... Germany, December 16 Eppendorf has ... and Verigene(R) SP systems for,infringement of European ... "Method for the,identification and/or the quantification of ... and all imports of the respective products ... authorities are required to confiscate any,violating products. ...
(Date:12/15/2009)... -- Epeius Biotechnologies Corporation, an emerging leader in ... validation of the cutting-edge science behind its lead ... the world rediscovered the Cyclin G1 gene ... pathogenesis and disease progression, and thus a prime ... NIH National Cancer Institute investigating the role of ...
Breaking Biology Technology:Indiana Industry, University and Community Leaders Capitalize on Next Generation of State's Life Sciences Growth 2Indiana Industry, University and Community Leaders Capitalize on Next Generation of State's Life Sciences Growth 3Indiana Industry, University and Community Leaders Capitalize on Next Generation of State's Life Sciences Growth 4Indiana Industry, University and Community Leaders Capitalize on Next Generation of State's Life Sciences Growth 5Sequenom Appoints Two New Board Members 2Sequenom Appoints Two New Board Members 3Eppendorf Successfully Initiates Import ban Against Nanosphere, Inc. for the Countries of the European Union 2Scientists Rediscover Gene Target for Cancer Therapy 2Scientists Rediscover Gene Target for Cancer Therapy 3
... in the field of electrospinning for applications primarily within ... Zeus, Inc. announces a new technology platform in ... fibers with thicknesses ranging from the nano to microscale. ... from solutions, pastes, and bioabsorbables. The result is a ...
... Probably not, but a hamster wearing a power-generating ... a new and renewable source of electricity. , And ... have also generated electrical current from a tapping finger ... and other handhelds one step closer to powering them ...
... On February 10, 2009, NeoStem, Inc. (NYSE Alternext ... Alternext US (the "Alternext") indicating that the Company is ... Company Guide (the "Guide"), which requires a listed company ... 3, 2008, the Company had announced that it planned ...
Other Biology Technology:Electrospinning: Emerging New Technology at Zeus 2Nanogenerators produce electricity from running rodents and tapping fingers 2Nanogenerators produce electricity from running rodents and tapping fingers 3NeoStem Receives Notice of Noncompliance from NYSE Alternext US 2
Request Info...
Laminin beta-1/gamma-1 (612C10)...
HSV 1 IgM...
100 ug affinity purified rabbit anti-JIP-1 polyclonal antibody. Reacts with mouse and rat. Perform well in Western blotting. Other applications have not been tested. Storage Temperature: -20C Shi...
Biology Products: