Navigation Links
fMRIs reveal brain's handling of low-priority ideas
Date:2/10/2010

SAN ANTONIO (Feb. 10, 2010) When we put an idea on the back burner, it goes into a processing area of the brain called the default-mode network. This network enables us to hold the low-priority idea in abeyance until a time when we aren't busy with something else.

"The default-mode network appears to be the brain's back burner for social decision making," said Peter T. Fox, M.D., director of the Research Imaging Institute at The University of Texas Health Science Center at San Antonio. "Usually these back-burner ideas relate to interpersonal interactions and decisions that can't readily be quantified and shouldn't be rushed."

Dr. Fox likened this to putting a computer batch job into background processing to wait until the system is less busy.

Role of genetics

A recently released study from the Research Imaging Institute, the Southwest Foundation for Biomedical Research and other institutions offers evidence that genetics plays a role in this back-burner setup, which has been shown to be abnormal in a variety of psychiatric disorders.

The work was described in the Jan. 18-22 online edition of Proceedings of the National Academy of Sciences (PNAS).

The default-mode network is one of several neural networks that operate whether the mind is at rest or is occupied doing a task. A separate PNAS paper, published in 2009 by Dr. Fox and the same collaborators, presented a strong case that all human behaviors may be properly viewed as cooperative interactions among these networks, Dr. Fox said.

Maps

The newer research estimated the importance of genetic effects on the default-mode network by creating maps of eight anatomically distinct regions within the network. These maps were obtained by functional magnetic resonance imaging (fMRI) studies in 333 individuals from 29 randomly selected, extended-family pedigrees.

Network connectivity and gray-matter density were correlated to genetic factors. "We found that more than 40 percent of the between-subject variance in functional connectivity within the default-mode network was under genetic control," Dr. Fox said.

Based on this information, it is possible new diagnostic tools could be considered for various psychiatric or neurological illnesses, he said.

The study also included collaborators from the Yale University School of Medicine, the University of Oxford in Oxford, U.K., and Imperial College in London, U.K. The project is an outgrowth of longstanding collaborations between the UT Health Science Center and the Southwest Foundation for Biomedical Research using tools for gene discovery. It is also a result of substantial collaborations between the Research Imaging Institute and Oxford to develop novel applications of imaging methods.

Future directions

"One long-term research goal is to test whether other intrinsically connected networks are also under genetic control, which we expect they will be," Dr. Fox said. "We also want to identify the genes that are controlling the default-mode network and other networks, and identify disorders associated with their abnormalities. A final goal is to develop treatment strategies."


'/>"/>

Contact: Will Sansom
sansom@uthscsa.edu
210-567-2579
University of Texas Health Science Center at San Antonio
Source:Eurekalert  

Related biology news :

1. Childhood obesity indicates greater risk of school absenteeism, Penn study reveals
2. Study begins to reveal clues to the cause and progression of sepsis
3. Comet probes reveal evidence of origin of life, scientists claim
4. Structure of 450 million year old protein reveals evolutions steps
5. UF scientists reveal how dietary restriction cleans cells
6. Neural stem cell study reveals mechanism that may play role in cancer
7. New method reveals substances on surfaces of any kind
8. Study reveals predation-evolution link
9. IDEMA Reveals Program Highlights for DISKCON USA 2007
10. Study reveals possible genetic risk for fetal alcohol disorders
11. IDEMA Reveals Program Highlights for DISKCON USA 2007
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
fMRIs reveal brain's handling of low-priority ideas
(Date:12/20/2016)... -- The rising popularity of mobility services such ... significant interest in keyless access systems. Following the ... (BLE), biometrics and near-field communication (NFC) are poised ... technologies in the automotive industry. This evolution from ... opens the market to specialist companies such as ...
(Date:12/16/2016)... 16, 2016 The global wearable medical device market, in ... 2021 from USD 5.31 billion in 2016, at a CAGR of ... ... technological advancements in medical devices, launch of a growing number of ... connectivity among healthcare providers, and increasing focus on physical fitness. ...
(Date:12/15/2016)... HILLS, Mich. , Dec. 15, 2016  There ... unlocking car doors or starting the engine. Continental will ... in Las Vegas . Through the ... (Passive Start and Entry) and biometric elements, the international ... field of vehicle personalization and authentication. "The ...
Breaking Biology News(10 mins):
(Date:1/21/2017)... Kan. , Jan. 20, 2017 Aratana ... therapeutics company focused on the licensing, development and commercialization ... Animal Pharm,s Best Company in North ... granted the award based on the FDA ... (grapiprant tablets), ENTYCE ® (capromorelin oral solution) ...
(Date:1/20/2017)... 20, 2017 Stock-Callers.com explores the ... influenced the most recent performances of select equities. In ... RGLS ), Abeona Therapeutics Inc. (NASDAQ: ... ), and Sage Therapeutics Inc. (NASDAQ: SAGE ... View Research, global Biotech market size is expected to reach $604.40 billion by ...
(Date:1/20/2017)... (PRWEB) , ... January 20, ... ... in Less Exposure Surgery (LES®) Technologies, announced today the next evolution in ... Pedicle Screw System platform). In contrast to the competition, SpineFrontier is focused ...
(Date:1/19/2017)... Ky. and HOUSTON ... Inc. ("NX Prenatal") today announced the formation of ... together leading clinicians and industry veterans who enhance ... company as it accelerates development of its novel ... to provide medical, clinical and strategic guidance for ...
Breaking Biology Technology: