Navigation Links
Zooming in on genetic shuffling
Date:7/10/2008

Genetic recombination, the process by which sexually reproducing organisms shuffle their genetic material when producing germ cells, leads to offspring with a new genetic make-up and influences the course of evolution. In the current issue of Nature, researchers at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, and the EMBL-European Bioinformatics Institute (EMBL-EBI) in Hinxton, UK, present the most precise map of genetic recombination yet. The study sheds light on fundamental questions about genetic shuffling and has implications for the tracking of disease genes and their inheritance.

In order to generate germ cells, sexually reproducing organisms undergo a complex series of cell divisions (meiosis) that includes the shuffling of genetic material inherited from the two parents. Equivalent chromosomes from mother and father pair up and exchange sections of DNA in a process called crossover. In a different type of recombination, called non-crossover, a small piece of DNA is copied from one chromosome onto the other without reciprocal exchange leading to gene conversion. Non-crossovers are minute events with a subtler effect than the exchange of larger fragments, but both types of recombination can increase genetic diversity and explain why organisms of the same species differ in many ways. Both types of recombination can also act to separate the transmission of neighbouring genes, which are normally inherited together.

The groups of Lars Steinmetz at EMBL and Wolfgang Huber at EMBL-EBI have produced the most detailed map to date of recombination events in the yeast genome.

"Our map has the highest resolution of recombination events that currently exists for any organism. We can locate crossovers and even hard-to-trace non-crossovers, typically with a precision of about 80 bases. This resolution is 20 times higher than in any existing yeast map and more than 360 times higher than a recent human map,"
'/>"/>

Contact: Anna-Lynn Wegener
wegener@embl.de
49-622-138-7452
European Molecular Biology Laboratory
Source:Eurekalert

Page: 1 2

Related biology news :

1. Genetic Engineering & Biotechnology News reports on novel hit-to-lead drug discovery
2. HapMap browsing and DDDP methods for genetic analysis featured in CSH Protocols
3. Political participation is partially rooted in genetic inheritance
4. International team identifies 21 new genetic risk factors for Crohns disease
5. Why do people vote? Genetic variation in political participation
6. Automated microfluidic device reduces time to screen small organisms for genetic studies
7. Drug reverses mental retardation caused by genetic disorder
8. Perspective: Policies must keep pace with genetic progress
9. Known genetic risk for Alzheimers in whites also places blacks at risk
10. Scientists confirm that parts of earliest genetic material may have come from the stars
11. Spradling receives Gruber Foundation Genetics Prize for new genetic techniques
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/25/2014)... the age girls reach puberty is influenced by ,imprinted genes,a ... contributes the gene. This is the first evidence that ... and details of this study were published today in the ... known as menarche, is a marker for the timing of ... of menses varies between girls, is an inherited trait, and ...
(Date:7/24/2014)... YORK, NY (July 24, 2014) Scientists at ... Institute are one step closer to creating a ... a patient,s own cells. , For the ... (iPS) cells lines from skin samples of patients ... developed an accelerated protocol to induce these stem ...
(Date:7/24/2014)... the use of native animal species for food or ... a significant factor in the decline of many species ... study indicates that more than half of the species ... and hornbills., "By surveying not only the meat made ... eaten inside the forest by hunters and brought to ...
Breaking Biology News(10 mins):Could age of first period influence development of diseases in older women? 2NYSCF scientists one step closer to cell therapy for multiple sclerosis patients 2
... SEATTLE Harmit Singh Malik, Ph.D., an evolutionary ... the 2010 Vilcek Prize for Creative Promise in Biomedical ... cash prize, for his research on the co-evolution of ... "immigrant achievement in biomedical science and arts." Malik was ...
... to our understanding of the complex chain of chemistry that ... University of Vermont (UVM), the University of Utah, Vanderbilt University ... demonstrated for the first time the specific activity of the ... integrity of DNA in humans and other mammals. Their work ...
... the sun were easy, we wouldn,t still have the greenhouse ... And while solar energy systems work moderately well in hot ... small percentage of the general energy demand. A new ... source that may be on your dinner plate tonight. ...
Cached Biology News:Dr. Harmit Malik receives Vilcek Prize for creative promise in biomedical science 2Mouse work: New insights on a fundamental DNA repair mechanism 2A new energy source from the common pea 2
(Date:7/25/2014)... of bacteria live in each person,s digestive tract. Scientists ... and stave off harmful infections, but their role in ... shed light on the role of these bacteria, a ... Alm recently tracked fluctuations in the bacterial populations of ... described in the July 25 issue of the journal ...
(Date:7/25/2014)... Albany, New York (PRWEB) July 25, 2014 ... Transparency Market Research, "Biological Drugs Market - Global Industry ... 2020," the global biological drugs market is estimated at ... grow at a CAGR of 10.1% from 2014 to ... million in 2020. , The biological drugs market is ...
(Date:7/25/2014)... July 25, 2014 Lawrence Livermore scientists ... Thomson Reuters list of " The World's Most Influential ... of the 3,000 researchers who were identified by analyzing ... those who published the highest-impact work (2002-2012 and 2012-2013). ... on combustion modeling . , "This recognition is ...
(Date:7/25/2014)... At the request of the AMA, the ... for the public comment period (Docket No. FAA-2014-0396) for ... established by Congress as part of the FAA Modernization ... the new deadline for comments as September 23, 2014. ... published in the Federal Register on July 25, 2014, ...
Breaking Biology Technology:Monitoring the rise and fall of the microbiome 2Monitoring the rise and fall of the microbiome 3Biological Drugs Market: Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2014 - 2020 2Biological Drugs Market: Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2014 - 2020 3Scientists Burst onto Influential List for Combustion Research 2Scientists Burst onto Influential List for Combustion Research 3Scientists Burst onto Influential List for Combustion Research 4FAA Grants Comment Extension at the Request of AMA 2
... Blocks of carbon nanotubes can be used to create ... study by researchers at Rensselaer Polytechnic Institute. , Taking ... researchers repeatedly squeezed a 3-millimeter nanotube block and discovered ... pressure sensor. No matter how many times or how ...
... Systems, Inc. (Sparta),the maker of TrackWise(R), and the ... announced that its TrackWise solution has,been chosen by ... development, manufacturing and marketing of specialized products for,critical ... complaint handling,processes. TrackWise provides organizations with a ...
... Human Genome,Sciences, Inc. (Nasdaq: HGSI ) today ... its financial results for the quarter ended,September 30, 2007. ... 1, 2007. (Logo: http://www.newscom.com/cgi-bin/prnh/20010612/HGSLOGO ) The ... will be,held on Thursday, November 1, 2007, at 11:00 ...
Cached Biology Technology:The sensitive side of carbon nanotubes: Creating powerful pressure sensors 2The sensitive side of carbon nanotubes: Creating powerful pressure sensors 3Protherics UK Ltd. Chooses TrackWise for Corrective Action and Preventive Action (CAPA) Management 2Human Genome Sciences To Sponsor Conference Call To Discuss Third Quarter 2007 Financial Results 2
cysteine and glycine-rich protein 2,...
... pan B (B220), 4.5 m, coated ... efficient positive isolation or depletion of ... or lymph node cell suspensions. B220 ... cells and lytically active subsets of ...
Gap junction protein, beta 2, 26kDa (connexin 26) Antigen: Peptide...
NAP-2 (5C7)...
Biology Products: