Navigation Links
Zeroing in on more powerful enzymes for degrading persistent pollutants
Date:11/16/2011

Laval, November 16, 2011 For the first time, researchers have identified two important strategies for optimizing the effects of the enzymes involved in degrading persistent pollutants such as PCBs. These scientific advances, achieved by Professor Michel Sylvestre of Centre INRSInstitut Armand-Frappier in conjunction with U.S. and Indian researchers, will serve not only to help develop effective biocatalysts for resolving environmental pollution problems, but also to synthesize new chemical compounds of biopharmaceutical interest.

Certain chemical components, like PCBs, PAHs, and CFCs, are toxic biosphere pollutants that are resistant to microbial degradation. Microbial catabolic enzymes are unable to effectively metabolize them. The results obtained by Professor Sylvestre and his colleagues open up new possibilities for boosting the effectiveness of these enzymes to oxidize such compounds.

Professor Sylvestre's research team has shown that it is possible to obtain more flexible mutant enzymes by replacing some of their amino acids. Moreover, they have updated a sophisticated mechanism that helps boost the enzyme's performance not only with regard to the natural substrate, but also any other substrates it can metabolize. As such, more effective new enzymes can be developed using genetic engineering.

"From a green chemistry perspective, the results of our research could allow us to apply these enzymes to biocatalysis processes to synthesize biologically active compounds (such as flavonoids) that have strong antioxidant properties," explained Professor Michel Sylvestre, also an enzyme engineering specialist.


'/>"/>

Contact: Gisele Bolduc
gisele.bolduc@adm.inrs.ca
418-654-2501
INRS
Source:Eurekalert

Page: 1

Related biology news :

1. Zeroing in on quantum effects
2. Powerful antibody-based strategy suggests a new therapeutic approach to diabetes and obesity
3. Powerful antioxidant resveratrol prevents metabolic syndrome in lab tests: U of A study
4. New fossils demonstrate that powerful eyes evolved in a twinkling
5. Finding is a feather in the cap for researchers studying birds big, powerful eyes
6. Giant fire-bellied toads brain brims with powerful germ-fighters
7. New device promises safer way to deliver powerful drugs
8. Structure of DNA repair complex reveals workings of powerful cell motor
9. K-State research channels powerful Kansas wind to keep electricity running
10. Researchers develop curious snapshot of powerful retinal pigment and its partners
11. Cancer Research Institute invests $450k in Oncovir to manufacture powerful immune stimulant
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/13/2015)... , April 13, 2015  higi, a leading ... ways to more fully engage with their communities around ... industry-leading, privacy protected and secure API.  ... enables the most accessible, affordable, and convenient vehicle to ... The API will allow ...
(Date:4/8/2015)... 2015  Infinisource, a leading provider of SaaS-based Human ... a leading supplier of biometric identification and security ... most advanced biometrically-enabled time clock, the companies announced ... is setting a bold, new standard for the ... small and mid-size employer. When connected to the ...
(Date:4/2/2015)... , April 2, 2015 At its ... Salt Lake City , the American College of ... five new directors to its Board.  Members of the ... ACMG and for forming and advancing its policies and ... genetics profession. "It,s an eventful time in ...
Breaking Biology News(10 mins):higi Launches Seamless Access to HIPAA-Compliant Health Outcomes and Activity Data 2higi Launches Seamless Access to HIPAA-Compliant Health Outcomes and Activity Data 3iSolved Time Clock Offers Unmatched Accuracy due to Morpho Biometrics 2iSolved Time Clock Offers Unmatched Accuracy due to Morpho Biometrics 3American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 2American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 3American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 4American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 5American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 6American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 7American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 8
... According to the World Bank, China has one of ... only to the United States in emissions of carbon dioxide, ... home to 20 of the worlds 30 most air-polluted cities. ... acid rain and water pollution, scientists at UC Riverside and ...
... the structure of human bones is vastly different than ... how some debilitating bone disorders are treated. Researchers ... in Newmarket, and the BAM Federal Institute of Materials ... toughness and stiffness of bone is predominantly due to ...
... Ninety-seven years after an American was hanged in London in ... British history, forensic science at Michigan State University is producing ... Crippen was hanged for murdering and dismembering his showgirl wife, ... the police in hot pursuit. Loaded with enough sordid details ...
Cached Biology News:UC-Riverside partners with Chinese university to address China's environmental problems 2UC-Riverside partners with Chinese university to address China's environmental problems 3New research on structure of bones raises questions for treatment of osteoporosis 2Science casts doubt on famous British murder case 2Science casts doubt on famous British murder case 3
(Date:5/4/2015)... , May 4, 2015  Soligenix, Inc. (OTCQB: ... developing products that address unmet medical needs in the ... it will be presenting preclinical data from three of ... Defense Science and Technology Conference on May 12-14, 2015 ... at 701 Convention Plaza, St. Louis MO ...
(Date:5/4/2015)... , May 4, 2015   Sentrian ™, the ... has teamed with the Scripps Translational Science Institute ... on 1,000 patients with chronic obstructive pulmonary disease (COPD), ... and is the nation,s third leading cause of death. ... CareMore Health System , a wholly owned subsidiary of ...
(Date:5/1/2015)... DIEGO , May 1, 2015 ... company engaged in the development of biosimilar therapeutics ... announced today that its first quarter 2015 financial ... 2015, before the open of market. At 8:30 am ... call to discuss the financial results and provide ...
(Date:5/1/2015)... May 1, 2015 According ... Market by Product (Equipment, Consumables), by Type (Monoclonal, Polyclonal), ... Labs, Research Institutes) - Analysis & Global Forecast ... the global Antibody Production Market for the forecast ... expected to reach $2.572 Billion by 2019 from ...
Breaking Biology Technology:Soligenix Announces Presentation and Poster at the 2015 Chemical and Biological Defense Science and Technology Conference in St. Louis, MO 2Soligenix Announces Presentation and Poster at the 2015 Chemical and Biological Defense Science and Technology Conference in St. Louis, MO 3Soligenix Announces Presentation and Poster at the 2015 Chemical and Biological Defense Science and Technology Conference in St. Louis, MO 4Soligenix Announces Presentation and Poster at the 2015 Chemical and Biological Defense Science and Technology Conference in St. Louis, MO 5Soligenix Announces Presentation and Poster at the 2015 Chemical and Biological Defense Science and Technology Conference in St. Louis, MO 6Soligenix Announces Presentation and Poster at the 2015 Chemical and Biological Defense Science and Technology Conference in St. Louis, MO 7Soligenix Announces Presentation and Poster at the 2015 Chemical and Biological Defense Science and Technology Conference in St. Louis, MO 8Soligenix Announces Presentation and Poster at the 2015 Chemical and Biological Defense Science and Technology Conference in St. Louis, MO 9Soligenix Announces Presentation and Poster at the 2015 Chemical and Biological Defense Science and Technology Conference in St. Louis, MO 10Soligenix Announces Presentation and Poster at the 2015 Chemical and Biological Defense Science and Technology Conference in St. Louis, MO 11Soligenix Announces Presentation and Poster at the 2015 Chemical and Biological Defense Science and Technology Conference in St. Louis, MO 12CareMore, Scripps Translational Science Institute, and Sentrian Launch Landmark Study of Remote Patient Monitoring for COPD Population 2CareMore, Scripps Translational Science Institute, and Sentrian Launch Landmark Study of Remote Patient Monitoring for COPD Population 3CareMore, Scripps Translational Science Institute, and Sentrian Launch Landmark Study of Remote Patient Monitoring for COPD Population 4CareMore, Scripps Translational Science Institute, and Sentrian Launch Landmark Study of Remote Patient Monitoring for COPD Population 5Pfenex To Report First Quarter 2015 Results and Provide Business Update on Thursday, May 14, 2015 2Antibody Production Market worth $2.572 Billion by 2019 2Antibody Production Market worth $2.572 Billion by 2019 3Antibody Production Market worth $2.572 Billion by 2019 4
... In LESS Instrumentation Is Selected for Industry Leader LESS ... Jan. 29 Cambridge Endo, a pioneer in the ... Surgery or SPA) market, is pleased to announce that ... industry leaders selected to be on a LESS panel ...
... of first-in-class multivalent therapies for cancerREDWOOD SHORES, Calif., Jan. ... it has entered into a $24 million private placement ... this financing, investments will be made in three tranches: ... December 31, 2009 and $8 million before December 31, ...
... evolves content and advertising offerings to life science community , ... ... to its online community for life science careers and industry resources. ... a partnership with the Journal of Visualized Experiments (JoVE)., , , ...
Cached Biology Technology:Cleveland Clinic Selects Laparoendoscopic Single-Site Surgery (LESS) as One of the Top Ten Innovations of 2009 2Omnitura Therapeutics Announces Private Placement Financing 2BioSpace Partners with Journal of Visualized Experiments (JoVE) to Offer Peer-Reviewed Scientific Video Content on BioSpace.com 2BioSpace Partners with Journal of Visualized Experiments (JoVE) to Offer Peer-Reviewed Scientific Video Content on BioSpace.com 3