Navigation Links
Zeroing in on more powerful enzymes for degrading persistent pollutants
Date:11/16/2011

Laval, November 16, 2011 For the first time, researchers have identified two important strategies for optimizing the effects of the enzymes involved in degrading persistent pollutants such as PCBs. These scientific advances, achieved by Professor Michel Sylvestre of Centre INRSInstitut Armand-Frappier in conjunction with U.S. and Indian researchers, will serve not only to help develop effective biocatalysts for resolving environmental pollution problems, but also to synthesize new chemical compounds of biopharmaceutical interest.

Certain chemical components, like PCBs, PAHs, and CFCs, are toxic biosphere pollutants that are resistant to microbial degradation. Microbial catabolic enzymes are unable to effectively metabolize them. The results obtained by Professor Sylvestre and his colleagues open up new possibilities for boosting the effectiveness of these enzymes to oxidize such compounds.

Professor Sylvestre's research team has shown that it is possible to obtain more flexible mutant enzymes by replacing some of their amino acids. Moreover, they have updated a sophisticated mechanism that helps boost the enzyme's performance not only with regard to the natural substrate, but also any other substrates it can metabolize. As such, more effective new enzymes can be developed using genetic engineering.

"From a green chemistry perspective, the results of our research could allow us to apply these enzymes to biocatalysis processes to synthesize biologically active compounds (such as flavonoids) that have strong antioxidant properties," explained Professor Michel Sylvestre, also an enzyme engineering specialist.


'/>"/>

Contact: Gisele Bolduc
gisele.bolduc@adm.inrs.ca
418-654-2501
INRS
Source:Eurekalert

Page: 1

Related biology news :

1. Zeroing in on quantum effects
2. Powerful antibody-based strategy suggests a new therapeutic approach to diabetes and obesity
3. Powerful antioxidant resveratrol prevents metabolic syndrome in lab tests: U of A study
4. New fossils demonstrate that powerful eyes evolved in a twinkling
5. Finding is a feather in the cap for researchers studying birds big, powerful eyes
6. Giant fire-bellied toads brain brims with powerful germ-fighters
7. New device promises safer way to deliver powerful drugs
8. Structure of DNA repair complex reveals workings of powerful cell motor
9. K-State research channels powerful Kansas wind to keep electricity running
10. Researchers develop curious snapshot of powerful retinal pigment and its partners
11. Cancer Research Institute invests $450k in Oncovir to manufacture powerful immune stimulant
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/17/2014)... Ill. A drug under clinical trials to treat ... broad-spectrum drugs that act against various bacteria, fungal infections ... by University of Illinois chemists and collaborators. , Led ... team determined the different ways the drug SQ109 attacks ... to target other pathogens from yeast to malaria ...
(Date:4/17/2014)... West Orange, NJ. April 16, 2014. Kessler Foundation ... for $1.8 million from the Department of Defense ... PhD, is principal investigator for the randomized, double-blinded, ... to improve bone and muscle strength after spinal ... Human Performance & Engineering Research at Kessler Foundation. ...
(Date:4/17/2014)... Down syndrome - or trisomy 21 - is the ... from a chromosomal abnormality where cells of affected individuals ... the human genome). A study conducted by Stylianos Antonarakis ... and Development at the University of Geneva (UNIGE) Faculty ... on how the extra chromosome 21 upsets the equilibrium ...
Breaking Biology News(10 mins):Multitarget TB drug could treat other diseases, evade resistance 2Kessler Foundation awarded Department of Defense grant for spinal cord injury research 2Trisomy 21: How an extra little chromosome throws the entire genome off balance 2Trisomy 21: How an extra little chromosome throws the entire genome off balance 3
... of the 20th International AIDS Conference (AIDS 2014) to ... today announced 19 major plenary presentations, focusing on the ... Plenary sessions will open each day of the conference, which ... over 200 countries. "We are excited to have ...
... Scientists have found that Neanderthals organized their living spaces in ... that once again shows similarities between these two close cousins. ... Canadian Journal of Archaeology , indicate that Neanderthals butchered ... parts of their shelters. "There has been this idea ...
... the Arctic, as part of the Catlin Arctic Survey, has ... beneath the ocean surface are likely to battle for survival ... copepods that move large distances, migrating vertically across a wide ... The increasing level of carbon dioxide in our ...
Cached Biology News:20th International AIDS Conference (AIDS 2014) plenary speakers announced 220th International AIDS Conference (AIDS 2014) plenary speakers announced 3New evidence suggests Neanderthals organized their living spaces 2New evidence suggests Neanderthals organized their living spaces 3Arctic study shows key marine food web species at risk from increasing CO2 2
(Date:1/15/2014)... VA (PRWEB) January 15, 2014 Two ... have continued their sponsorship of an annual competition for ... in, and access to, innovative STEM study. The competition ... TEAMS: Tests of Engineering Aptitude, Mathematics, and Sciences ...
(Date:1/15/2014)... January 15, 2014 AudioNotch is the ... therapy for the treatment of tinnitus. Patients listen to ... and over a period of weeks to months, their tinnitus ... in two forms: Notched Music and Notched White Noise. Now, ...
(Date:1/14/2014)... 2014  3D Communications, a leading provider of strategic communications services to ... events in the United States and ... Cox , JD, is returning to the firm,s Washington, ... 3D after more than two years of service as Associate Commissioner ...
(Date:1/14/2014)... iLab Solutions, the leader in core facility management ... Product Strategy. In this role, Michelle will work with current ... in the development of iLab products. Her main goal will ... to the scientific community by offering the most advanced, user-friendly, ...
Breaking Biology Technology:Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 2Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 3Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 4Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 5Former FDA Associate Commissioner Returns To 3D Communications 2iLab Solutions Announces Michelle Detwiler as the New Director of Product Strategy 2
... HOUSTON, July 16 US Oncology Holdings, Inc. ... 2008 second quarter,financial results on Thursday, August 7, ... has been scheduled at 11:00,a.m., EDT, for the ... In this call, representatives of US Oncology,s management,team ...
... -- Federal Court Enters Consent Judgment Terminating Litigation ... (NYSE: WYE ) and,Impax Laboratories Inc. today ... U.S. patent infringement litigation pertaining to Impax,s proposed,generic ... approved by the United States District Court for ...
... fractal character of neurons led in turn ... structures act back recursively upon their DNA code ... name in neuroscience for his tensor network ... another far-reaching discovery borne out.,This insight has now received ...
Cached Biology Technology:Wyeth and Impax Announce Final Settlement of Effexor XR Patent Suit 2Wyeth and Impax Announce Final Settlement of Effexor XR Patent Suit 3Principle of Recursive Genome Function Supersedes Dogmas; By Andras Pellionisz, Online Ahead of Print; (Scientific Visionary Vindicated) 2Principle of Recursive Genome Function Supersedes Dogmas; By Andras Pellionisz, Online Ahead of Print; (Scientific Visionary Vindicated) 3Principle of Recursive Genome Function Supersedes Dogmas; By Andras Pellionisz, Online Ahead of Print; (Scientific Visionary Vindicated) 4Principle of Recursive Genome Function Supersedes Dogmas; By Andras Pellionisz, Online Ahead of Print; (Scientific Visionary Vindicated) 5
... Molecular Probes is pleased to offer ... the ultrasensitive detection of primary amines. ... Indiana University, the ATTO-TAG reagents are ... (OPA), naphthalene-2,3-dicarboxaldehyde (NDA) and anthracene-2,3-dicarboxaldehyde, all ...
...
Microlite 2+ Plate, round bottom; an irradiated, high binding surface with enhanced dynamic range, extra high reflectivity and minimal cross talk for low signal luminescent reactions....
Immulon 4 HBX 1x12 Strip, flat bottom; high binding extra surface with special resin and irradiation, offers maximum protein uptake....
Biology Products: