Navigation Links
Zebrafish may hold the answer to repairing damaged retinas and returning eyesight to people
Date:1/31/2013

Zebrafish, the staple of genetic research, may hold the answer to repairing damaged retinas and returning eye-sight to people.

University of Alberta researchers discovered that a zebrafish's stem cells can selectively regenerate damaged photoreceptor cells.

Lead U of A researcher Ted Allison says that for some time geneticists have known that unlike humans, stem cells in zebrafish can replace damaged cells involved in many components of eyesight. Rods and cones are the most important photoreceptors. In humans, rods provide us with night vision while cones give us a full colour look at the world during the day-time.

What was not known says Allison was whether stem cells could be instructed to only replace the cones in its retina. This could have important implications for human eyesight.

"This is the first time in an animal research model that stem cells have only repaired damaged cones," said Allison. "For people with damaged eyesight repairing the cones is most important because it would restore day-time colour vision.

The researchers say that to date almost all success in regenerating photoreceptor cells has been limited to rods not cones. Most of these previous experiments were conducted on nocturnal rodents, animals that require good night vision so they have far more rods than cones.

"This shows us that when cones die in a cone-rich retina, it is primarily cones that regenerate," said Allison. "This suggests the tissue environment provides cues to instruct stem cell how to react."

The researchers say this shows some hope for stem cell therapy that could regenerate damaged cones in people, especially in the cone-rich regions of the retina that provide daytime/colour vision.

Allison says the next step for his team is to identify the particular gene in zebrafish gene that activates repair of damaged cones.


'/>"/>

Contact: Brian Murphy
brian.murphy@ualberta.ca
780-492-6041
University of Alberta
Source:Eurekalert

Page: 1

Related biology news :

1. Surprising teaching tool in K-12 science education -- Zebrafish research
2. Zebrafish study explains why the circadian rhythm affects your health
3. Zebrafish -- the stars of biomedicine
4. Zebrafish provide insights into causes and treatment of human diseases
5. Zebrafish research shows how dietary fat regulates cholesterol absorption
6. Versatility of zebrafish research highlighted at international conference
7. Environmental estrogens affect early developmental activity in zebrafish
8. Zebrafish could hold the key to understanding psychiatric disorders
9. Better housing conditions for zebrafish could improve research results
10. Chicken and egg question (and answer) for rural Uganda
11. Seafood, wild or farmed? The answer may be both
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... YORK and POINT ROBERTS, Washington ... news source covering leading sectors including technology and tech stocks, ... Privacy marketplace featuring master pickpocket and security consultant Apollo ... is stolen and talks about the Wocket™ biometric smart wallet, ...
(Date:1/22/2015)... , Jan. 22, 2015 Research and Markets ... addition of the "Global Wearable Technologies Market ... Share, Overview, Trends and Forecast 2014-2020" report ... Technologies are smart devices that can be worn ...
(Date:12/24/2014)... Dec. 23, 2014  Since its launch in December 2014, the ... the pain of trying to remember their usernames and passwords ... to their smartphones. To assist people who have struggled to ... that created 1U and focuses on redefining identity, announced today ...
Breaking Biology News(10 mins):Apollo Robbins Talks about the Illusion of Personal Safety and How Easily Your Wallet is Stolen; If a Wocket Wallet is Stolen the Thief Can't do Anything With it! 2Apollo Robbins Talks about the Illusion of Personal Safety and How Easily Your Wallet is Stolen; If a Wocket Wallet is Stolen the Thief Can't do Anything With it! 3Global Wearable Technologies Market and Applications, Opportunities, Industry Analysis, Segmentation, Size, Growth, Share, Overview, Trends and Forecast 2014-2020 21U Offers Best Solution to the Username / Password Dilemma: For FREE! 21U Offers Best Solution to the Username / Password Dilemma: For FREE! 3
... material already used in absorbable surgical sutures and other ... to patients with brain infections, scientists are reporting in ... on the brain,s surface, could reduce the need for ... treatment, they say in the journal ACS Chemical ...
... have a limited capacity to soak up atmospheric carbon ... University. The study, available online in the journal ... atmospheric carbon dioxide could alter the carbon and nitrogen ... woodland plots over an 11-year period, the researchers found ...
... have extensive surgery are four times more likely to ... has found. The findings in a new paper ... systematic review and meta-analysis published in the prestigious journal ... surgery to treat breast cancer increases the risk of ...
Cached Biology News:Breast cancer surgery linked to swollen arm syndrome 2
(Date:2/26/2015)... S&P Capital IQ (MHFI) announced today that ... MabVax Therapeutics Holdings Inc . MabVax ... company focused on the development of vaccine and antibody-based ... of cancer. MabVax has discovered a pipeline of human ... generated by patients who have been immunized against targeted ...
(Date:2/26/2015)... --  Synageva BioPharma Corp. (NASDAQ: ... for rare disorders, today reported 2014 full year ... objectives, and financial guidance.  Synageva,s management team will ... EST to review the financial results and provide ... call by telephone, please dial (877) 445-4603 for ...
(Date:2/26/2015)... (PRWEB) February 26, 2015 The Movement ... demonstration to support life extension technologies and awareness. The ... Universal Coordinated Time, on March 21st 2015, in a ... , Eric Schulke, Founder of MILE, says, “Our ... with urgency. The Movement for Indefinite Life Extension is ...
(Date:2/26/2015)... 2015 BioEnterprise today announced that ... than $2 billion in growth funding during the past ... strategic sources, state – including the Ohio Third Frontier ... billion has been raised in the past five years. ... of the BioEnterprise Midwest Healthcare Growth Capital  Report. ...
Breaking Biology Technology:S&P Capital IQ Initiates Coverage on MabVax Therapeutics Holdings Inc. in S&P Capital IQ Factual Stock Reports 2S&P Capital IQ Initiates Coverage on MabVax Therapeutics Holdings Inc. in S&P Capital IQ Factual Stock Reports 3S&P Capital IQ Initiates Coverage on MabVax Therapeutics Holdings Inc. in S&P Capital IQ Factual Stock Reports 4S&P Capital IQ Initiates Coverage on MabVax Therapeutics Holdings Inc. in S&P Capital IQ Factual Stock Reports 5Synageva BioPharma Reports 2014 Full Year Financial Results 2Synageva BioPharma Reports 2014 Full Year Financial Results 3Synageva BioPharma Reports 2014 Full Year Financial Results 4Synageva BioPharma Reports 2014 Full Year Financial Results 5Synageva BioPharma Reports 2014 Full Year Financial Results 6Synageva BioPharma Reports 2014 Full Year Financial Results 7Synageva BioPharma Reports 2014 Full Year Financial Results 8Synageva BioPharma Reports 2014 Full Year Financial Results 9Indefinite Life Extension Activists Organize Online Demonstration 2Indefinite Life Extension Activists Organize Online Demonstration 3More Than $2 Billion Invested in Northeast Ohio Bioscience Start-Up Companies Since 2002 2More Than $2 Billion Invested in Northeast Ohio Bioscience Start-Up Companies Since 2002 3More Than $2 Billion Invested in Northeast Ohio Bioscience Start-Up Companies Since 2002 4
... in the United States searches for an Indian company so ... banyan tree? , ,Protesters during the industrial age screamed against ... possible destruction of society. They later protested about the manufacturing ... to the roar as we enter into a global tide ...
... GE Healthcare will provide digital imaging systems to ... the company announced on Monday. , ,Englands National Health ... images to be transmitted among hospitals so that experts ... about $18 billion. The deal with GE Healthcare is ...
... am sitting with an angry Mediterranean Sea roaring at my ... start-ups as the first winter storm hits Tel Aviv. I ... Israel, taking an assessment of the technology markets here and ... strikes me on this visit is the presumed gap between ...
Cached Biology Technology:Outsourcing fills gaps and drives U.S. back toward innovation 2Outsourcing fills gaps and drives U.S. back toward innovation 3Innovation thrives in Europe 2Innovation thrives in Europe 3