Navigation Links
Youthful stem cells from bone can heal the heart, Temple scientists report
Date:9/4/2013

(Philadelphia, PA) - Many people who survive a heart attack find themselves back in the hospital with a failing heart just years later. And the outcome often is unfavorable, owing to limited treatment options. But scientists at Temple University School of Medicine's Cardiovascular Research Center (CVRC) recently found hope in an unlikely source stem cells in cortical, or compact, bone. In a new study, they show that when it comes to the regeneration of heart tissue, these novel bone-derived cells do a better job than the heart's own stem cells.

According to the study's senior investigator, Steven R. Houser, Ph.D., FAHA, Chairperson of Temple's Department of Physiology and Director of the CVRC, it is early days for cortical bone-derived stem cells (CBSCs). Nonetheless, his team's findings, featured on the cover of the August 16th issue of Circulation Research, have considerable implications for stem cell therapy for the heart.

A major challenge in the treatment of heart attack is early intervention, which is key to reducing the chances for long-term complications, such as heart failure. When it comes to stem cells, Houser said, "The strategy is to inject the cells right after [a heart attack]." Currently, though, that approach works only in animal studies. To make it work in humans, Houser explained, "we need cells right off the rack and ready to go clinically."

CBSCs could be those cells. Stem cells are youthful by degrees, and CBSCs are considered some of the most pluripotent like human newborns, nave and ready to become anything. But while CBSCs and similarly pluripotent stem cells retain the ability to develop into any cell type needed by the body and sometimes bring their youthful energy to the aid of mature cells making them especially appealing for therapeutics they also have the potential to wander off course, possibly landing themselves in unintended tissues. Cardiac stem cells, on the other hand, are a little more
'/>"/>

Contact: Jeremy Walter
Jeremy.Walter@tuhs.temple.edu
215-707-7882
Temple University Health System
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Research identifies how mouth cells resist Candida infection
2. Statins may slow human aging by protecting against telomere shortening: A feature of senescent cells
3. UC Davis team spikes stem cells to generate myelin
4. Why are some cells more cancer prone?
5. Harvard Stem Cell researchers create cells that line blood vessels
6. UCI-led study reveals how SARS virus hijacks host cells
7. Fetal tissue-derived stem cells may be ideal source for repairing tissues and organs
8. Ingredient in turmeric spice when combined with anti-nausea drug kills cancer cells
9. Celery, artichokes contain flavonoids that kill human pancreatic cancer cells
10. Sympathetic neurons cross talk with pancreas cells during early development
11. Lampreys provide hints to ancient immune cells
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/11/2014)... Salk Institute for Biological Studies, BGI, and other ... and reliability of the existing targeted gene correction ... which could significantly increased gene-correction efficiency in human ... online in Cell Stell Cell provides ... therapy. , The combination of stem cells and ...
(Date:7/11/2014)... July 11, 2014 Researchers have pioneered ... images. The new technology, called Virtual Finger, allows ... structures like neurons and synapses using the flat ... technology makes 3D imaging studies orders of magnitude ... an unprecedented level across many areas of experimental ...
(Date:7/11/2014)... the normal circumstances, astrocytes participate in normal ... and exhibit therapeutic and repairing effects on ... have found that nerve cells differentiated from ... reduced viability, which produces influences on subsequent ... General Hospital, Hebei United University, China demonstrated ...
Breaking Biology News(10 mins):A new genome editing method brings the possibility of gene therapies closer to reality 2Virtual finger enables scientists to navigate and analyze complex 3D images 2
... COLUMBUS, Ohio From the paleolithic diet to the raw ... they believe our ancient ancestors ate. But some of these ... new book on the evolution of the use of food and ... can learn from what our ancestors ate, many of our more ...
... E. coli food poisoning outbreaks developed more ... trials because of lack of commercial interest. University of ... neutralises the toxin produced by E. coli , which ... The team of scientists Dr Adrienne Paton, Associate Professor ...
... to phase out nuclear power by 2022 has reopened an ... Japan, which is still coming to terms with events at ... the SETAC journal Environmental Toxicology and Chemistry adds ... using research from the Chernobyl disaster. The issue ...
Cached Biology News:An 'all natural' diet? There's no such thing 2An 'all natural' diet? There's no such thing 3Potential treatment for deadly E. coli disease 2
(Date:7/10/2014)... , July 10, 2014  Franciscan ... use of capnography for respiratory monitoring outside ... of healthcare leaders in embracing state-of-the-art patient ... effectively patients are breathing and can alert ... By measuring the amount of carbon dioxide ...
(Date:7/10/2014)... -- Research and Markets ( http://www.researchandmarkets.com/research/s3bqj2/photonic ) has ... Integrated Circuit (Monolithic Integration, Hybrid Integration, Module Integration) ... their offering. http://photos.prnewswire.com/prnh/20130307/600769 ... traces its roots in the latter half of ... went unexplored and unfulfilled for several decades owing ...
(Date:7/10/2014)... D.C., June 17, 2014 Using microscopic polymer ... specific gases, researchers at MIT,s Quantum Photonics Laboratory ... levels in the parts-per-billion range. Optical sensors are ... their high signal-to-noise ratio, compact, lightweight nature, and ... gas sensors had been developed before, the MIT ...
(Date:7/10/2014)... lithium-ion batteries that power our laptops and electric vehicles ... single charge with the help of a sponge-like silicon ... replace the graphite traditionally used in one of the ... the energy storage capacity of graphite. A paper describing ... published today in Nature Communications . , "Silicon ...
Breaking Biology Technology:Franciscan St. Anthony Health-Crown Point Underscores Patient Safety Commitment Through Expanded Use of Capnography 2International Photonic Integrated Circuit (Monolithic Integration, Hybrid Integration, Module Integration) Market - Forecasts to 2019 2Swell new sensors 2Silicon sponge improves lithium-ion battery performance 2Silicon sponge improves lithium-ion battery performance 3
... Dimensions , a Wisconsin data management firm, announced last ... the New York metro area by partnering with MailSurity ... company that develops paper scanning and data recognition technology, ... its software to process forms. , ,Parascript's software is ...
... rude noise somebody makes in a meeting after too ... population also knows that Enterprise Resource Planning isnt some ... single check to a vendor. , ,Im not out ... is apparently less obvious is that ERP systems dont ...
... provider of rich-media systems and software, is deploying its ... announced. , ,Sonic Foundry and media services provider ... Connect's new Virtual Law Viewer system for the ... MediaSite presentation recorders with the BxVideo RMXPRES hosting services, ...
Cached Biology Technology:Steering a project portfolio takes more than expensive software 2Steering a project portfolio takes more than expensive software 3Streaming video could make courtrooms into Internet conference calls 2
... product contains 5 ml Dynabeads Tosylactivated (4.5 ... (tosyl) reactive groups. For coupling of antibodies ... on initial coupling with covalent binding of ... sulphydryll groups (SH)) occurringovernight. Coupling reactions can ...
Carrier-Free Recombinant Human Flt-3/Flk-2 Ligand (Flt3/Flk2 Ligand, Flt3L, Flt3-L, Flk2L, Flk2-L) 100 ug...
... II inhibitor (IC50 = 59.2 M). ... H 32 O 13 MolWeight: ... RT CAS: ... Soluble to 100 mM in DMSO ...
NAP-2 (5C7)...
Biology Products: