Navigation Links
Yerkes researchers create first transgenic prairie voles
Date:12/1/2009

Researchers at the Yerkes National Primate Research Center, Emory University, have successfully generated the first transgenic prairie voles, an important step toward unlocking the genetic secrets of pair bonding. The future application of this technology will enable scientists to perform a host of genetic manipulations that will help identify the brain mechanisms of social bonding and other complex social behaviors. This advancement may also have important implications for understanding and treating psychiatric disorders associated with impairments in social behavior. The study is available in the December issue of Biology of Reproduction.

Lead researcher Zoe Donaldson, PhD, and her colleagues adapted transgenic technology to the prairie vole, a naturally occurring monogamous rodent that is being used to discover the brain mechanisms underlying monogamous pair bonds.

"Domesticated lab rats and mice dominate biomedical research, but wild rodent species with more complex social behaviors are better suited for investigating the biology of the social brain. Until now, genetic engineering among rodents has been limited to lab mice and rats," says Donaldson.

Single-cell prairie vole embryos were injected with a lentivirus containing a gene found in glowing jellyfish. The gene encodes a green fluorescent protein, which glows under the appropriate conditions. The prairie vole that developed from this embryo expressed the green fluorescent protein throughout its body, and the foreign gene was passed on to the offspring for multiple generations.

Larry Young, PhD, a Yerkes-based senior investigator on the study and an expert in social behavior, will next use this technology to determine whether monogamy and its associated social behaviors can be affected by manipulating a single gene. Researchers are also investigating ways to refine this technology in order to alter gene expression in certain brain regions as well as at certa
'/>"/>

Contact: Emily Rios
erios@emory.edu
404-727-7732
Emory University
Source:Eurekalert

Page: 1 2

Related biology news :

1. Yerkes researchers identify language feature unique to human brain
2. Researchers identify proteins involved in new neurodegenerative syndrome
3. Texas researchers and educators head for Antarctica
4. MGH researchers describe new way to identify, evolve novel enzymes
5. University of Pennsylvania researchers develop formula to gauge risk of disease clusters
6. U of MN researchers discover noninvasive diagnostic tool for brain diseases
7. U of Minnesota researchers discover noninvasive diagnostic tool for brain diseases
8. Researchers discover new strategies for antibiotic resistance
9. Researchers find new taste in fruit flies: carbonated water
10. Binghamton University researchers investigate evolving malaria resistance
11. UIC researchers find promising new targets for antibiotics
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/19/2014)...   LaunchKey , the first decentralized mobile authentication and ... Things era, today announced the close of $3 million ... by Metamorphic Ventures with participation from ENIAC Ventures, Crosslink ... LaunchKey has raised $4 million to date, and will ...
(Date:12/17/2014)... and Markets ( http://www.researchandmarkets.com/research/9zq33j/global_chemical ) has announced ... 2015-2019" report to their offering. ... upcoming in this market is the increasing demand for ... recording of patient data for quick and correct diagnosis ...
(Date:12/11/2014)... WINSTON SALEM, N.C. , Dec. 10, 2014  That blood ... for quite a while. Hypertension – the medical term for ... in the early 1800s, and the inflatable cuff that,s used ... That doesn,t, however, mean there,s nothing new about hypertension, its ...
Breaking Biology News(10 mins):LaunchKey Raises $3 Million in Additional Funding Led by Metamorphic Ventures 2LaunchKey Raises $3 Million in Additional Funding Led by Metamorphic Ventures 3Global Chemical Sensor Market 2015-2019: Key Vendors are Abbott Laboratories, Bayer, Hoffmann La-Roche, Johnson & Johnson, NGK Spark Plugs and Robert Bosch 2Research points to need for new approaches to treatment of high blood pressure 2Research points to need for new approaches to treatment of high blood pressure 3Research points to need for new approaches to treatment of high blood pressure 4
... UCLA and a team of enterprising UCLA scientists envisioning a ... In 1996, a unique collaboration of leading UCLA scientists ... Inc. and the company now stands to reap $537 ... one of the largest Los Angeles-based private biotech firms poised ...
... gallons of hazardous waste resulting from the nations nuclear ... Washington state called Hanford. Beneath this desert landscape ... thousands of tons of chemicals are captured within the ... subsurface flow paths. These paths create uncertainties about ...
... making, Birds of Peru describes the birds of Peru ... in color, and concise descriptive text. The first two ... Douglas Stotz, PhD, are conservation ecologists and ornithologists in ... Museum will host a free public event launching the ...
Cached Biology News:Biotech Co. founded by UCLA Scientists to be acquired by Astellas, Pharma Inc. 2Biotech Co. founded by UCLA Scientists to be acquired by Astellas, Pharma Inc. 3Where does stored nuclear waste go? 2Lavishly illustrated guide to Peru's birds describes 1,800 species 2
(Date:12/24/2014)... Md. , Dec. 24, 2014  United Therapeutics Corporation ... Inc. (NYSE: MDT ) has submitted a ... Administration (FDA) for the use of Medtronic,s SynchroMed ® ... developed catheter) for use with United Therapeutics, Remodulin ® ...
(Date:12/24/2014)... , Dec. 24, 2014  Vermillion, Inc. (Nasdaq:   ... disease, announced today that the Company closed its ... Investment Management, Jack W. Schuler , Birchview ... were $10.5 million, before offering expenses.  The proceeds ...
(Date:12/24/2014)... 23, 2014 “Preparative & Process ... Flash), Consumables (Columns, Solvents, Buffers, Valves, Guages, Seals), ... Agriculture) - Forecasts to 2019” provides a detailed ... current market trends, and strategies impacting the preparative ...
(Date:12/24/2014)... (PRWEB) December 23, 2014 Earlier this year ... Sherley, director of the Adult Stem Cell Technology Center, LLC ... under appreciated unique property of adult tissue stem cells. ... the Past, Important for the Future,” embodied the essence of ...
Breaking Biology Technology:United Therapeutics Announces Submission Of Pre-Market Approval Application For Implantable Drug Infusion System To Deliver Remodulin 2United Therapeutics Announces Submission Of Pre-Market Approval Application For Implantable Drug Infusion System To Deliver Remodulin 3United Therapeutics Announces Submission Of Pre-Market Approval Application For Implantable Drug Infusion System To Deliver Remodulin 4Vermillion Announces Closing of Equity Financing 2Vermillion Announces Closing of Equity Financing 3Preparative and Process Chromatography Market is expected to reach $9 billion by 2019 - New Report by Marketsandmarkets 2Preparative and Process Chromatography Market is expected to reach $9 billion by 2019 - New Report by Marketsandmarkets 3Preparative and Process Chromatography Market is expected to reach $9 billion by 2019 - New Report by Marketsandmarkets 4Adult Stem Cell Technology Center, LLC’s Director Sherley's Address on What’s Holding Back Regenerative Medicine Featured on Omics Group Website 2Adult Stem Cell Technology Center, LLC’s Director Sherley's Address on What’s Holding Back Regenerative Medicine Featured on Omics Group Website 3Adult Stem Cell Technology Center, LLC’s Director Sherley's Address on What’s Holding Back Regenerative Medicine Featured on Omics Group Website 4
... Israel, April 7 InSightec Ltd. announced,today that the ... for the company,s ExAblate(R) 2000 MR-guided Focused Ultrasound,(MRgFUS) system ... Under the new labeling, the agency allows,physicians to treat ... previous,restriction to only treat up to half the fibroid ...
... -- China Sky One,Medical, Inc. ("China Sky One ... ), a,leading fully integrated pharmaceutical company producing,over-the-counter drugs ... that an extension notification filed with the Securities ... 10-K on March 31, 2009, is,related to a ...
... Filtration and Separations Society (AFS) will be holding its 22nd ... Minnesota. , ... Minneapolis, MN (PRWEB) April 7, 2009 ... be holding its 22nd Annual Conference, May 4-7, 2009 at the ...
Cached Biology Technology:FDA Approves Label Change for Non-Invasive Fibroid Treatment 2FDA Approves Label Change for Non-Invasive Fibroid Treatment 3China Sky One Medical, Inc. Provides Update on Filing Form 10-K 2China Sky One Medical, Inc. Provides Update on Filing Form 10-K 3University of Minnesota Professor Dr. David Pui to Speak at American Filtration and Separation Society Conference 2University of Minnesota Professor Dr. David Pui to Speak at American Filtration and Separation Society Conference 3
...
Form: Concentrated Applications: ELISA...
Form: Ready to use Applications: ELISA...
Recombinant Mouse Serpin A1/alpha-1-Antitrypsin, CF Protein Family: Coagulation, Serine Protease Regulators...
Biology Products: