Navigation Links
Yale researchers explain why cancer 'smart drugs' may not be so smart
Date:5/11/2011

ith Cetuximab.

In their second related study, published online in the current issue of the journal Biochemistry, Maihle and her team show that newly developed reagents to measure sEGFR in blood and other human tissues can detect a second unrelated cell surface protein in tumor cells: alpha-5 integrin.

"This important finding suggests that the naturally occurring sEGFR protein may play a complex role in cell adhesion and migrationtwo cellular processes important in the spread of cancer," said Maihle, who is a member of Yale Cancer Center. "Together these studies demonstrate an unanticipated level of complexity in EGFR signaling and assay development, and suggest new ways to overcome current challenges associated with clinical testing for this important cancer target."


'/>"/>

Contact: Karen N. Peart
karen.peart@hotmail.com
203-432-1326
Yale University
Source:Eurekalert

Page: 1 2

Related biology news :

1. Reforesting rural lands in China pays big dividends, Stanford researchers say
2. Chemistry researchers receive patent for new scientific measurement instrument
3. USDA researchers, collaborators sequence genomes of fungi that threaten wheat, poplars
4. Researchers get new view of how water and sulfur dioxide mix
5. OGI genomics researchers awarded $23 million
6. Columbia researchers find green roof is a cost-effective way to keep water out of sewers
7. Einstein researchers find key gene in childhood cancer
8. Researchers show heparan sulfate adjusts functions of growth factor proteins
9. Penn researchers develop technique for measuring stressed molecules in cells
10. Researchers see a picture of threat in the brain: Work may lead to new model of neuroinflammation
11. Researchers join forces to cure deadly childhood disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/5/2015)... August 5, 2015 According to ... Management Market by Software, Services, Vertical (BFSI, Airport, IT & ... - Global Forecast to 2020", published by MarketsandMarkets, defines ... globally into various segments. The global PIAM Market is ... $546.2 Million by 2019, at a CAGR of 14.9 ...
(Date:8/4/2015)... 2015 Research ... the addition of the "Digital Forensics ... Sub-Segment (Computer Forensics, Network Forensics, Mobile Device ... Vertical and Region - Global Forecast to ... By Component (Hardware, Software, and Service), ...
(Date:7/31/2015)... SHENZHEN , Kina, 31. juli 2015 ... ) bliver afholdt af BGI fra den 22. - 25. ... Konferencen fejrer sin 10-års fødselsdag i år. ... verdens mest indflydelsesrige årlige møder på ,omik,-feltet, og er ... forsamlinger. ICG-10 fokuserer på nylige gennembrud ...
Breaking Biology News(10 mins):Physical Identity and Access Management Market Worth $546.2 Million by 2019 2Physical Identity and Access Management Market Worth $546.2 Million by 2019 3Physical Identity and Access Management Market Worth $546.2 Million by 2019 4Digital Forensics Market - The Market Represents a Compound Annual Growth Rate (CAGR) of 11.3% From 2015 to 2020 2Den 10. internationale konference om Genomics (ICG-10) åbner i oktober 2
... pharmaceutical industry is struggling to deal with bacteria that ... is the similar struggle in agribusiness to deal with ... is widely used in farming practice. The herbicide, ... in Monsanto,s Roundup products and also in herbicides produced ...
... Mich. Sheng Yang He, plant biologist at Michigan ... most-innovative plant scientists as part of a $75 million ... Medical Institute and the Gordon and Betty Moore Foundation ... Laboratory, and 14 other researchers from around the country. ...
... HOUSTON (June 16, 2011) Researchers at The ... have been awarded nearly $1 million to investigate Adenovirus-36 ... The grant is being awarded by the Federal Emergency ... The study will examine the relationship of Ad-36 to ...
Cached Biology News:Scientists learn how horseweed shrugs off herbicide 2Scientists learn how horseweed shrugs off herbicide 3Scientists learn how horseweed shrugs off herbicide 4Scientists learn how horseweed shrugs off herbicide 5MSU plant scientist named one of the nation's most innovative researchers 2UTHealth awarded FEMA grant to explore novel obesity risk factor among firefighters 2UTHealth awarded FEMA grant to explore novel obesity risk factor among firefighters 3
(Date:9/2/2015)... Sept. 2, 2015 Research and ... addition of Jain PharmaBiotech,s new report ... their offering. An increasing ... biotechnology industries is anticipated. Nanotechnology will be ... - from formulations for optimal delivery to ...
(Date:9/2/2015)... DUBLIN , Sep. 02, 2015 ... ) has announced the addition of Jain PharmaBiotech,s ... Companies" to their offering. This ... as a characteristic that can be objectively measured ... or pathogenic processes as well as pharmacological responses ...
(Date:9/2/2015)... 2, 2015  Neurotech Pharmaceuticals, Inc., announced today ... multicenter Phase 2 clinical trial of NT-503 Encapsulated ... recurrent subfoveal choroidal neovascularization secondary to age related ... vascular endothelial growth factor (VEGF) receptor protein continuously ... "This landmark proof-of-concept study will evaluate NT-503 ECT ...
(Date:9/2/2015)... ZIONA, Israel , September 2, 2015 /PRNewswire/ ... today announced the intent of the National Institute of Allergy ... of Health (NIH) within the Department of Health and Human ... be held in the United States ... of BiondVax,s universal flu vaccine candidate, Multimeric-001 (M-001), as a ...
Breaking Biology Technology:Global Nanobiotechnology Applications, Markets and Companies Report 2015-2024 2Global Nanobiotechnology Applications, Markets and Companies Report 2015-2024 3Updated 2015 Biomarkers Report - Latest Technologies, Markets and Companies Insights to 2024 with over 1,000 References 2Updated 2015 Biomarkers Report - Latest Technologies, Markets and Companies Insights to 2024 with over 1,000 References 3Neurotech Announces First Patient Enrolled in Novel Anti-VEGF Encapsulated Cell Therapy Study 2Neurotech Announces First Patient Enrolled in Novel Anti-VEGF Encapsulated Cell Therapy Study 3Neurotech Announces First Patient Enrolled in Novel Anti-VEGF Encapsulated Cell Therapy Study 4BiondVax Announces Intent to Launch a Phase 2 Trial in the United States in Collaboration with the U.S. National Institutes of Health 2BiondVax Announces Intent to Launch a Phase 2 Trial in the United States in Collaboration with the U.S. National Institutes of Health 3
... D Garteiz, TexMS Analytical Services, Houston, TX , ... A Varian 1200L LC/MS/MS system was used for ... therapeutic agents to the urinary tract using a urethra suppository mode of ... tract disease is a major health problem in the U.S. and will ...
... , ... Oxidative stress, radiation and other external insults ... diverse as bacteria, yeast, drosophila, rodents and man (Friedberg et al. ... to allow time for DNA repair processes to occur. If however, the system ...
... Ryan Varian Australia Pty. Ltd., Mulgrave, 3170, Victoria, Australia , ... The role of major, minor and trace levels of ... In particular, research on the value of trace elements to the diagnosis, ... The advent of atomic absorption (AA) techniques and the ...
Cached Biology Technology:Quantitation of Oxybutynin in Rabbit Plasma Using the Varian 1200L LC/MS/MS System 2Quantitation of Oxybutynin in Rabbit Plasma Using the Varian 1200L LC/MS/MS System 3DNA Damage and Repair - Quantification of Sub-Cellular Events Using Automated Confocal Imaging 2DNA Damage and Repair - Quantification of Sub-Cellular Events Using Automated Confocal Imaging 3DNA Damage and Repair - Quantification of Sub-Cellular Events Using Automated Confocal Imaging 4DNA Damage and Repair - Quantification of Sub-Cellular Events Using Automated Confocal Imaging 5Analysis of Blood Serum on the Liberty Series II ICP-AES with the axially-viewed plasma 2Analysis of Blood Serum on the Liberty Series II ICP-AES with the axially-viewed plasma 3Analysis of Blood Serum on the Liberty Series II ICP-AES with the axially-viewed plasma 4Analysis of Blood Serum on the Liberty Series II ICP-AES with the axially-viewed plasma 5Analysis of Blood Serum on the Liberty Series II ICP-AES with the axially-viewed plasma 6Analysis of Blood Serum on the Liberty Series II ICP-AES with the axially-viewed plasma 7Analysis of Blood Serum on the Liberty Series II ICP-AES with the axially-viewed plasma 8Analysis of Blood Serum on the Liberty Series II ICP-AES with the axially-viewed plasma 9Analysis of Blood Serum on the Liberty Series II ICP-AES with the axially-viewed plasma 10Analysis of Blood Serum on the Liberty Series II ICP-AES with the axially-viewed plasma 11Analysis of Blood Serum on the Liberty Series II ICP-AES with the axially-viewed plasma 12
Laminin beta-2 (C4)...
Anti-MD-2 (IN) Host: rabbit polyclonal Species Reactivity: human, mouse, rat Applications: WB, IHC Storage: 4C...
VMAT 2 (N-19)...
Calcium Channel alpha 2 delta-2 Purified Anti-Mouse, Anti-Rat, Anti-Human clone 42, Isotype Mouse IgG 1 , 150 µg Consult technical datasheet for details....
Biology Products: