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Yale researchers develop a way to monitor engineered blood vessels as they grow in patients
Date:11/30/2011

ged the mice with MRI and found that it was possible to track the cells labeled with contrast agent, but not possible to track the cells that were not labeled. This suggests that using MRI and cellular contrast agents to study cellular changes in the tissue-engineered blood vessels after they are implanted is an effective way to monitor these types of vessels.

"This is great news for patients with congenital heart defects, who have to undergo tissue grafting, but that's only the tip of the scalpel," said Gerald Weissmann, M.D., Editor-in-Chief of the FASEB Journal. "As we progress toward an era of personalized medicinewhere patients' own tissues and cells will be re-engineered into replacement organs and treatmentswe will need noninvasive ways to monitor what happens inside the body in real time. This technique fulfills another promise of nanobiology."


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Contact: Cody Mooneyhan
cmooneyhan@faseb.org
301-634-7104
Federation of American Societies for Experimental Biology
Source:Eurekalert

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