Navigation Links
Yale researchers develop a way to monitor engineered blood vessels as they grow in patients
Date:11/30/2011

Bethesda, MDUsing magnetic resonance imaging (MRI) and nanoparticle technology, researchers from Yale have devised a way to monitor the growth of laboratory-engineered blood vessels after they have been implanted in patients. This advance represents an important step toward ensuring that blood vessels, and possibly other tissues engineered from a patient's own biological material, are taking hold and working as expected. Until now, there has been no way to monitor the growth and progress of engineered tissues once they were implanted. This research was published in the December 2011 issue of the FASEB Journal (http://www.fasebj.org).

"We hope that the important findings from our study will serve as a valuable tool for physicians and scientists working to better understand the biological mechanisms involved in tissue engineering," said Christopher K. Breuer, M.D., co-author of the study from the Interdepartmental Program in Vascular Biology and Therapeutics at Yale University School of Medicine in New Haven, CT. "Resulting advances will hopefully usher in a new era of personalized medical treatments where replacement vessels are specifically designed for each patient suffering from cardiac anomalies and disease."

To make this advance, scientists used two different groups of cells to make tissue-engineered blood vessels. In the first group, the cells were labeled with the MRI contrast agent. In the second group, the cells were normal and did not have an MRI label. Cells from each group were then used to create separate laboratory-engineered blood vessels, which were implanted into mice. The purpose was to see whether the laboratory-engineered blood vessels made from cells that were labeled with the contrast agent would indeed be visible on MRI and to make sure that the addition of the contrast agent did not negatively affect the cells or the function of the laboratory-engineered vessels. Researchers ima
'/>"/>

Contact: Cody Mooneyhan
cmooneyhan@faseb.org
301-634-7104
Federation of American Societies for Experimental Biology
Source:Eurekalert

Page: 1 2

Related biology news :

1. NJIT researchers publish news of success with robots as learning tool
2. Researchers new recipe cooks up better tissue phantoms
3. BUSM researchers develop blood test to detect membranous nephropathy
4. WSU researchers use a 3-D printer to make bone-like material
5. Abstinence-only education does not lead to abstinent behavior, UGA researchers find
6. Body rebuilding: Researchers regenerate muscle in mice
7. UCLA researchers engineer blood stem cells to fight melanoma
8. BWH researchers develop a vaccine prototype stronger than traditional vaccines
9. The immune system has protective memory cells, researchers discover
10. Researchers awarded $3.2 million from NIH to pioneer advanced biomolecule discovery technology
11. 3 researchers in the Amazon clear up doubts as to the benefits of ecotourism
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/4/2014)... of Medicine announced today that it is a ... the Bill & Melinda Gates Foundation. Laura ... Reproductive Sciences; and Vice Chair of Research and ... will pursue an innovative global health and development ... Fetal Neurodevelopment.", Grand Challenges Explorations (GCE) funds individuals ...
(Date:11/4/2014)... VILNIUS, Lithuania , Nov. 4, 2014 /PRNewswire/ ... identification technologies, today announced that the latest version ... place in the Ongoing MINEX evaluation ... interoperability of fingerprint algorithms using the INCITS 378 ... a mandatory requirement in public tenders in ...
(Date:11/2/2014)... month,s issue of Physics World , James Dacey ... "valley of death" to take their innovations from the ... the gruelling challenge facing all start-up companies as they ... physicists because of two main factors: physics-based inventions are ... often turn out to be a lot more complicated ...
Breaking Biology News(10 mins):Temple University School of Medicine receives Grand Challenges Explorations grant 2Neurotechnology Places Second in Ongoing MINEX Ranking for Fingerprint Matching Algorithms 2Neurotechnology Places Second in Ongoing MINEX Ranking for Fingerprint Matching Algorithms 3The 'valley of death' facing physics start-ups 2
... that some biological structures, like the brain or the ... explain. Biologists have proposed various ways that so-called ,irreducibly ... bit. But a new study proposes an alternative route. ... becoming more intricate, say authors Dan McShea and Wim ...
... Ohio American adults who prepare their own meals and ... on one of those activities at the expense of the ... a 10-minute increase in food preparation time was associated with ... for both men and women. The finding applied to single ...
... helpers (nannies) in a cichlid fish allow the dominant male ... and territory, according to new research published today in ... 30 days which corresponds to one breeding cycle in ... and the University of Bern (Switzerland) studied the investment strategies ...
Cached Biology News:Study proposes alternative way to explain life's complexity 2Study proposes alternative way to explain life's complexity 3Exercise or make dinner? Study finds adults trade one healthy act for another 2Exercise or make dinner? Study finds adults trade one healthy act for another 3
(Date:11/26/2014)...  Roka Bioscience, Inc. (NASDAQ: ROKA ), a ... the detection of foodborne pathogens, today announced that Paul ... th Annual Healthcare Conference on December 2, 2014 at ... York Palace in New York, NY . ... Company, its operations, strategies and prospects may be discussed. To ...
(Date:11/24/2014)... Belgium , Nov. 24, 2014 ... focused on developing diagnostic tests for cancer and other conditions, ... will be presented at the Science for Business BioWin Day ... Belgium . The data come from VolitionRx,s lung cancer ... Pneumology department of the Centre Hospitalier Universitaire (CHU) de Liege ...
(Date:11/24/2014)... (PRWEB) November 24, 2014 Continental ... patient populations into clinical trials at its mid-Atlantic ... , “Continental was created with the idea of ... a fundamental role in medical advances," said Continental's ... syphilis experiment to the immortal cell line of ...
(Date:11/24/2014)... 2014 Senior Vice President, General ... leadership skills, business acumen Elsevier , ... products and services, congratulates Diane Bartoli , Senior ... Workflow, Elsevier Clinical Solutions, for being recognized in the ... Awards issue of Profiles in Diversity Journal ...
Breaking Biology Technology:Roka Bioscience to Present at the Piper Jaffray Healthcare Conference 2VolitionRx to Present Positive Data from Pilot Lung Cancer Study at BioWin Day 2014 2VolitionRx to Present Positive Data from Pilot Lung Cancer Study at BioWin Day 2014 3VolitionRx to Present Positive Data from Pilot Lung Cancer Study at BioWin Day 2014 4VolitionRx to Present Positive Data from Pilot Lung Cancer Study at BioWin Day 2014 5VolitionRx to Present Positive Data from Pilot Lung Cancer Study at BioWin Day 2014 6At Continental Clinical Solutions, CEO Saleh Stevens Focuses on Diversity in Clinical Trial Recruitment at Maryland Site 2At Continental Clinical Solutions, CEO Saleh Stevens Focuses on Diversity in Clinical Trial Recruitment at Maryland Site 3Elsevier Clinical Solutions' Diane Bartoli Featured In Profiles in Diversity Journal's 13th Annual Women Worth Watching Issue 2Elsevier Clinical Solutions' Diane Bartoli Featured In Profiles in Diversity Journal's 13th Annual Women Worth Watching Issue 3
... and Families, EMERYVILLE, Calif., April 15 ... two new health care areas designed to,soothe patients ... to offer health resources. The Carol Ann,Read Breast ... procedures, all in one location, for the quickest ...
... Able to Detect a Single Cancer Cell Through In Vivo ... ... Caliper Life,Sciences, Inc. (Nasdaq: CALP ) today introduced Bioware(R) Ultra cell ... in vivo imaging applications. Bioware Ultra cell lines are,10 to 100 times ...
... Pittsburgh-based Foundation,Radiology Group (FRG), a full-service ... diagnostic images for hospitals,announced today that James ... the,position of Chief Medical Officer. The appointment ... nationwide network of radiology physician groups to,provide ...
Cached Biology Technology:Alta Bates Summit Medical Center Opens Two Warm, Supportive Patient Centers: Carol Ann Read Breast Health Center and Family Resource Center 2Alta Bates Summit Medical Center Opens Two Warm, Supportive Patient Centers: Carol Ann Read Breast Health Center and Family Resource Center 3Increased Light Leads to Early Detection: Caliper Life Sciences Introduces Bioware(R) Ultra Cancer Cell Lines 2Increased Light Leads to Early Detection: Caliper Life Sciences Introduces Bioware(R) Ultra Cancer Cell Lines 3James W. Backstrom, M.D., Named Chief Medical Officer of Foundation Radiology Group 2James W. Backstrom, M.D., Named Chief Medical Officer of Foundation Radiology Group 3
IHC detection kit for PCNA in cells and tissues...
... Immunogen: Synthetic peptide derived from the ... protein. Specificity: Reacts with the ... Reactivity: Human Mouse (positive controls: WNT1-transfected ... lysates and mouse Mouse-1 cell lysates). ...
The pYES2 vector is designed for native expression of your protein of interest in S. cerevisiae. It contains the URA3 gene for selection in yeast and 2 origin for high-copy maintenance....
... cAMP - [125I] Direct SPA ... SPA.Includes lysis reagents that eliminate lengthy ... cAMP measurement (optional use).Range: 1.32-84.28 ng/ml ... pmol/ml).Overnight protocol.Store at 2-8 C. Category: ...
Biology Products: