Navigation Links
Worm genome offers clues to evolution of parasitism
Date:9/24/2008

, the worms live in a "resting" stage in which they don't eat or reproduce.

This suspended state, called dauer diapause, is thought to be the infective state of parasitic nematodes. According to the World Health Organization, parasitic nematodes infect about 2 billion people worldwide and severely sicken some 300 million.

The genome of P. pacificus is substantially larger and more complex than C. elegans. It has nearly 170,000 chemical bases and contains 23,500 protein-coding genes. By comparison, C. elegans and the human parasitic nematode Brugia malayi, whose genome was sequenced in 2007, only have about 20,000 and 12,000 protein-coding genes, respectively. Infection with B. malayi causes lymphatic filariasis, which can lead to elephantiasis, a grotesque enlargement of the arms, legs and genitals.

Interestingly, the P. pacificus genome contains a number of genes for cellulases - enzymes that are required to break down cell walls of plants and microorganisms. These genes are nonexistent in C. elegans, although they have been found in plant parasitic nematodes.

"Using genetic tools, we can analyze the development, behavior and ecology of this highly unusual worm to aid in understanding the evolutionary changes that allowed parasitism to occur," says co-author Richard K. Wilson, Ph.D., director of Washington University's Genome Sequencing Center.


'/>"/>

Contact: Caroline Arbanas
arbanasc@wustl.edu
314-286-0109
Washington University School of Medicine
Source:Eurekalert

Page: 1 2

Related biology news :

1. NC State researchers get to root of parasite genome
2. TGen investigators devise faster, cheaper way of analyzing the human genome
3. DOE JGI extends the capabilities of the Integrated Microbial Genome System
4. Leader of Human Genome Project honored with the Inamori Ethics Prize
5. ISU researchers help map first plant-parasitic nematode genome sequence
6. Trichoplax genome sequenced -- rosetta stone for understanding evolution
7. Genome of simplest animal reveals ancient lineage, confounding array of complex capabilities
8. Genome of saltwater creature could aid understanding of gene grouping
9. Cataloguing invisible life: Microbe genome emerges from lake sediment
10. Duke-NIEHS team shows how DNA repairs may reshape the genome
11. Significant impact factor boost for scientific journal Genome Research
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/7/2014)... , November 6, 2014 Leading ... for better mobile security revolutionizing online transactions.  Companies in focus ... Holdings Ltd. (NYSE: BABA ), Google Inc. (NASDAQ: ... ), eBay Inc. (NASDAQ: EBAY ) and MasterCard ... NXTD and NXTDW), a biometric authentication company focused on ...
(Date:11/6/2014)... predator. Except when that predator runs so fast that it ... size, is the fastest creature on Earth. Some of these ... about five miles per hour). The fastest human can do ... the tiger beetle, a person would have to hit 480 ... problem. At peak speeds, everything becomes a blur. They can,t ...
(Date:11/5/2014)... Redmond has dedicated his career to understanding the ... general audience. , As deputy director and regional ... Nevada,s Desert Research Institute, Redmond has more than ... and dissemination of climate data to the general ... in San Francisco on December 15-19, 2014 the ...
Breaking Biology News(10 mins):Universal Authentication Methods Provide More Secure Operations for Biometrics Devices - Company Joins FIDO Alliance for Consumer Protection 2Universal Authentication Methods Provide More Secure Operations for Biometrics Devices - Company Joins FIDO Alliance for Consumer Protection 3Universal Authentication Methods Provide More Secure Operations for Biometrics Devices - Company Joins FIDO Alliance for Consumer Protection 4Universal Authentication Methods Provide More Secure Operations for Biometrics Devices - Company Joins FIDO Alliance for Consumer Protection 5Universal Authentication Methods Provide More Secure Operations for Biometrics Devices - Company Joins FIDO Alliance for Consumer Protection 6The tiger beetle: Too fast to see 2Nevada climatologist to be honored at AGU Fall Meeting for lifetime of public outreach 2
... ROUGE Antarctica is home to the largest body of ... one thought that life could exist beneath the Antarctic ice ... places, because conditions were believed to be too extreme. However, ... spent a great deal of time in one of the ...
... El Salvador in the September issue of BioScience presents ... and monies sent to family members by emigrants have ... Susanna B. Hecht and Sassan S. Saatchi, employed socioeconomic ... increases in the area of El Salvador covered by ...
... of Illinois at Chicago researchers have identified new ... antibiotics can be delivered to treat infections. ... fighting infections caused by the pathogens which became ... associate director of UIC,s Center for Pharmaceutical Biotechnology ...
Cached Biology News:LSU professor looks for life in and under antarctic ice 2LSU professor looks for life in and under antarctic ice 3Population movements and money remittances spur forest regrowth 2UIC researchers find promising new targets for antibiotics 2
(Date:11/26/2014)... Bio-Techne Corporation (NASDAQ: TECH ) announced today ... serve in a newly created position of Senior Vice ... be responsible for managing the operations of Bio-Techne,s Protein ... in July 2014 and the recently acquired CyVek business. ... ProteinSimple develops and commercializes proprietary systems and consumables that ...
(Date:11/26/2014)... WARREN, N.J. , Nov. 25, 2014  Roka Bioscience, ... focused on providing advanced testing solutions for the detection of ... will present at the Piper Jaffray  26 th Annual ... conference will be held at The New York Palace in ... During this presentation, material information concerning the Company, its operations, ...
(Date:11/24/2014)... UAE, November 24, 2014 Five ... Bin Rashid Al Maktoum Awards for Medical Sciences", in ... Dubai, United Arab Emirates , on 15 December ... , The Carter Center which won the ... actively involved in numerous programs that aim to improve ...
(Date:11/24/2014)... Belgium , Nov. 24, 2014 ... focused on developing diagnostic tests for cancer and other conditions, ... will be presented at the Science for Business BioWin Day ... Belgium . The data come from VolitionRx,s lung cancer ... Pneumology department of the Centre Hospitalier Universitaire (CHU) de Liege ...
Breaking Biology Technology:Bio?Techne Announces Appointment Of Robert Gavin As Leader Of New Protein Platforms Division 2Bio?Techne Announces Appointment Of Robert Gavin As Leader Of New Protein Platforms Division 3Roka Bioscience to Present at the Piper Jaffray Healthcare Conference 2Five US Winners Among Recipients of Hamdan Medical Awards 2VolitionRx to Present Positive Data from Pilot Lung Cancer Study at BioWin Day 2014 2VolitionRx to Present Positive Data from Pilot Lung Cancer Study at BioWin Day 2014 3VolitionRx to Present Positive Data from Pilot Lung Cancer Study at BioWin Day 2014 4VolitionRx to Present Positive Data from Pilot Lung Cancer Study at BioWin Day 2014 5VolitionRx to Present Positive Data from Pilot Lung Cancer Study at BioWin Day 2014 6
... Feb. 2 Cephalon, Inc .,(Nasdaq: ... its option to,license worldwide rights to Lupuzor(TM), an investigational ... the promising interim,results of the ImmuPharma Phase IIb study. ... filings and subsequent commercialization of,the product. , ...
... , the first clinically proven natural stimulator of growth ... a more desirable "first step" approach to pursuing hormonal ... is only available through a ... increase the body,s own production and release of growth ...
... (NYSE Alternext US: CUR) announced today that Richard ... 11th Annual BIO CEO & Investor Conference to ... Waldorf=Astoria Hotel, New York City.(Logo: http://www.newscom.com/cgi-bin/prnh/20061221/DCTH007LOGO )Neuralstem,s ... at 10:00 a.m. Eastern Time.The presentation will be ...
Cached Biology Technology:Cephalon Exercises Option to License Worldwide Rights to ImmuPharma Product, Lupuzor 2Cephalon Exercises Option to License Worldwide Rights to ImmuPharma Product, Lupuzor 3Cephalon Exercises Option to License Worldwide Rights to ImmuPharma Product, Lupuzor 4Cephalon Exercises Option to License Worldwide Rights to ImmuPharma Product, Lupuzor 5Secretropin(R) - Effective, Preferable, Affordable as an Alternative to Injectable Growth Hormone - Gains Momentum 2Neuralstem to Present at the 11th Annual BIO CEO & Investor Conference 2
Microlite 2+ Plate, round bottom; an irradiated, high binding surface with enhanced dynamic range, extra high reflectivity and minimal cross talk for low signal luminescent reactions....
... 0-10 psi precision pressure regulator and pressurized syringe ... Faster liquid-switching Steady flow rate Microinjecting ... Can be added to any new ... any third-party manufacturer, even homemade. Connect to house ...
...
... purified polyclonal antibody to the Salmonella Common ... Isolated from a serum pool of goats ... This antibody is broadly reactive to Salmonella ... It has excellent specificity for Group ...
Biology Products: