Navigation Links
World's biggest heart model simulated at Université de Montréal

Montreal, January 18, 2008 Researchers from the Universit de Montral have used a supercomputer to conduct the largest-ever mathematical simulation of the electrical activity of a human heart a 2 billion element model to provide new insight into cardiac and other illnesses. Until recently, the worlds largest simulated hearts had a few million elements at most. The UdeM simulation was up to 1,000 times more detailed than previous models and will enable new scientific discoveries that would never have been possible otherwise.

The computer on which the simulation was performed, a 768-processor SGI Altix 4700, is the largest shared-memory computing system in Canada. Operated by the Rseau qubcois de calcul de haute performance (RQCHP), it is used by hundreds of Canadian researchers. Mark Potse and Alain Vinet, of the UdeMs Institute of Biomedical Engineering, routinely use 60 to 100 of these processors to run their simulations of the human heart. In late October, Potse and Vinet had the opportunity to use the entire SGI Altix system and its1.2TB of shared memory to solve the largest, most detailed heart model ever.

Two weeks to simulate full heartbeat

The researchers simulated five milliseconds of activation in a tissue block that included some properties of a real heart, such as fibre running in different directions. The simulation solved a system of two billion equations a dozen times. The test took two hours. A full heartbeat, Potse says, would take two weeks to simulate and his team cannot claim use of the entire supercomputer for such lengths yet. The purpose of the test was to show that when the next generation supercomputers becomes available, researchers will be able to use it effectively, said Vinet. This type of model is increasingly difficult to solve when it is larger. It was far from evident that this test was going to work.

With heart disease one of the leading causes of death in the Western world, discovering the electrical triggers of the various kinds of heart disease could lead to earlier diagnosis and new treatment breakthroughs. In order to understand what the mechanisms of the particular disease are, the heart must be modeled with enormous detail. Once disease mechanisms are fully understood, scientists will be able to devise the best drug or the best cure surgical or other remedies -- and doctors will be able to diagnose much more precisely. Without the use of computer models it can be hard to track the effects of a heart disease on the ECG.


Contact: S-J Desjardins
University of Montreal

Related biology news :

1. The best both of worlds -- how to have sex and survive
2. 390-million-year-old scorpion fossil -- biggest bug known
3. Abnormal fat metabolism underlies heart problems in diabetic patients
4. High blood pressure, low energy -- a recipe for heart failure
5. Human derived stem cells can repair rat hearts damaged by heart attack
6. Geron Demonstrates hESC-derived cardiomyocytes improve heart function after myocardial infarction
7. Heart of Herschel to be presented to media
8. Minimally invasive heart surgery research wins NIH award
9. A step toward tissue-engineered heart structures for children
10. Research explains link between cholesterol and heart disease
11. Eating competence may lower risk of heart disease
Post Your Comments:
(Date:10/29/2015)... Va. , Oct. 29, 2015 Daon, ... today that it has released a new version of ... customers in North America have ... IdentityX v4.0 also includes a FIDO UAF certified ... are already preparing to activate FIDO features. These customers ...
(Date:10/27/2015)... -- In the present market scenario, security is one ... verticals such as banking, healthcare, defense, electronic gadgets, and ... secure & simplified access control and growing rate of ... bank accounts, misuse of users, , and so on. ... and smartphones are expected to provide potential opportunities for ...
(Date:10/26/2015)...  Delta ID Inc., a company focused on bringing ... devices, announced its ActiveIRIS® technology powers the iris recognition ... by NTT DOCOMO, INC in Japan ... to include iris recognition technology, after a very successful ... May 2015, world,s first smartphone to have this capability. ...
Breaking Biology News(10 mins):
(Date:11/28/2015)... ... ... • Jeon Jin Bio Corp, a Korean Biotech venture company, has developed ... Bird Free, an oil-based, gel formula made from natural ... smell, taste and touch, enabling safe, effective avian control without toxic chemicals , ...
(Date:11/26/2015)... , England , November 26, 2015 /PRNewswire/ ... Medical, an innovative medical device company specializing in imaging technologies, ... from the European Commission as part of the Horizon 2020 ... company to carry out a large-scale clinical trial in breast ...      (Logo: , --> ...
(Date:11/25/2015)... Mass. , Nov. 25, 2015 Harvard ... biotechnology company developing bioengineered organ implants for life-threatening conditions, ... present at the LD Micro "Main Event" investor conference ... The presentation will be webcast live and posted for ... be available at the conference for one-on-one meetings on ...
(Date:11/25/2015)... PORTLAND, Oregon , November 25, 2015 /PRNewswire/ ... Deep Market Research Report is a professional and ... Genomics industry.      (Logo: ... basic overview of the industry including definitions, classifications, ... analysis is provided for the international markets including ...
Breaking Biology Technology: