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Women's health-related scientific findings presented by University of Pittsburgh researchers
Date:3/27/2008

omen with a previous preterm birth had higher concentrations of total cholesterol than women whose babies were born at term, and those whose babies were born earliest less than 34 weeks gestation had the highest concentrations, Janet M. Catov, Ph.D., and her colleagues report.

Women with preterm birth are at increased risk for cardiovascular disease, but mechanisms relating to these conditions are not well understood, said Dr. Catov, assistant professor of obstetrics, gynecology and reproductive sciences at Pitt and an investigator at MWRI. We wanted to see whether some of these cardiovascular risk factors observed during pregnancy persist into the postpartum period.

Dr. Catov and her colleagues compared information on 47 women who had delivered prior to 37 weeks gestation with data on 104 women with term births, at or more than 37 weeks gestation. Concentrations of total cholesterol, triglycerides, LDL and HDL also were collected an average of 7.4 years postpartum and compared.

We found that total cholesterol was an average of two to three times higher for women with a history of preterm birth compared to those with normal gestation births, said Dr. Catov, adding that results were similar for LDL and HDL cholesterol, even after adjustment for race, age, smoking and body weight.

Additional authors include James M. Roberts, M.D., and Roberta B. Ness, M.D., M.P.H., both of the University of Pittsburgh School of Medicine.

This is Abstract No. 204. Dr. Catov is presenting a poster at 10 a.m., PDT, March 27.


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Contact: Michele Baum
BaumMD@upmc.edu
412-647-3555
University of Pittsburgh Schools of the Health Sciences
Source:Eurekalert

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