Navigation Links
Women more depressed and men more impulsive with reduced serotonin functioning
Date:9/17/2007

Philadelphia, PA, September 17, 2007 Women and men appear to respond differently to the same biochemical manipulation. Major depressive disorder (MDD) is one of the most common mental disorders, and it is also one of the most studied. It is already known that reduced serotonin transmission contributes to the pathophysiology, or functional changes, associated with MDD and most of todays most popular antidepressants block the serotonin uptake site, also known as the transporter, in the brain. It is also known that people with MDD are frequently found to have impaired impulse control. A new study being published in the September 15th issue of Biological Psychiatry now reports on important sex and genetic differences in the way that men and women react to reductions in serotonin function, specifically in terms of their mood and impulsivity.

Using a technique in healthy participants called acute tryptophan depletion, which decreases serotonin levels in the brain, Walderhaug and colleagues found that men became more impulsive, but did not experience any mood changes in response to the induced chemical changes. However, women in this study reported a worsening of their mood and they became more cautious, a response commonly associated with depression. The researchers also discovered that the mood lowering effect in women was influenced by variation in the promotor region of the serotonin transporter gene (5-HTTLPR).

One of the studys authors, Dr. Espen Walderhaug, explains, We were surprised to find such a clear sex difference, as men and women normally experience the same effect when the brain chemistry is changed Although we have the same serotonergic system in the brain, it is possible that men and women utilize serotonin differently.

These findings highlight the complexity of studying and treating these disorders, as the interactive effects of gender and genetic coding impacted the outcomes in the men and women when their serotoner
'/>"/>

Contact: Jayne M. Dawkins
ja.dawkins@elsevier.com
215-239-3674
Elsevier
Source:Eurekalert

Page: 1 2

Related biology news :

1. Male circumcision reduces risk of HIV transmission from women to men
2. Variation in womens X chromosomes may explain differences among individuals, between sexes
3. Of mice and mens (and womens) contraceptives
4. Survey reveals women and doctors arent talking about HPV
5. Men Estimate Mens Risks Of Common Disorders Higher Than Women Do, And Vice Versa
6. Pregnant women at higher risk for HIV, Uganda study finds
7. Higher risk for cervical cancer seen among women infected with multiple HPV types
8. Women cautioned against using herbal supplements
9. Screen all at risk for HIV, plus pregnant women
10. Women feel more pain than men, research shows
11. Agreement will speed research on microbicides for women
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/18/2014)... A novel robotic system that can operate inside ... tested as part of a biomedical research partnership program ... aim of determining if the robot, in conjunction with ... more accurate, less costly, and less discomforting for the ... deliver prostate cancer therapies with greater precision. , Developed ...
(Date:9/18/2014)... starts a "frequent flyers" program, fruit flies surely would ... has hosted increasing numbers of fruit fly research studies. ... in April, and another is scheduled launch to the ... launch in December. , Fruit flies are biomedical research ... space. Model organisms can reveal the basis for health ...
(Date:9/18/2014)... foliage season that prompts millions of Americans to undertake jaunts ... possibly last a little longer within a century, according to ... in some areas of the United States as summer temperatures ... the journal Global Ecology and Biogeography . For instance, ... the state tree of New Hampshire could change color ...
Breaking Biology News(10 mins):Trial begins for MRI-compatible robot designed to improve accuracy of prostate biopsies 2Trial begins for MRI-compatible robot designed to improve accuracy of prostate biopsies 3Trial begins for MRI-compatible robot designed to improve accuracy of prostate biopsies 4Trial begins for MRI-compatible robot designed to improve accuracy of prostate biopsies 5Buzzing with activity: Fruit flies orbit Earth for science 2Buzzing with activity: Fruit flies orbit Earth for science 3Buzzing with activity: Fruit flies orbit Earth for science 4Fall foliage season may be later, but longer on warmer Earth 2Fall foliage season may be later, but longer on warmer Earth 3Fall foliage season may be later, but longer on warmer Earth 4
... at the University of South Florida (USF) College of Public ... rodent model that the earliest form of malaria parasites can ... recover, following treatment with the antimalarial drug artesunate. The ... PLoS ONE , suggests that this early-stage dormancy phenomenon ...
... 25, 2011 DST Health Solutions ... Community Health Plan (CCHP) has implemented its PowerMHC® ... Suite to help meet new market requirements and enhance ... implement a nurse assist line service for CCHP, which ...
... is getting even harder to find in the Sierra Nevada, ... the U.S. Forest Service and Oregon State University. A new ... have dropped 60 percent since the 1980sa decrease that may ... which they live, researchers say. Their findings appeared in the ...
Cached Biology News:Dormant malaria parsites in red blood cells may contribute to treatment failure 2DST Health Solutions' Integrated Care Management Suite Improves Care Quality, Population Management of 31,000+ Member Health Plan 2DST Health Solutions' Integrated Care Management Suite Improves Care Quality, Population Management of 31,000+ Member Health Plan 3Fewer marten detections in California forest linked to decline in habitat 2
(Date:9/19/2014)... 19, 2014 , The first ... for Paediatric Endocrinology (ESPE) Meeting  Investment supports ... research in the field of growth  , ... Germany , today announced the first recipients ... The awards were announced during a Satellite Symposium organized ...
(Date:9/18/2014)... September 18, 2014 HealthTronics, ... and interventional radiology products and services, announced that ... cryotherapy and cryoablation) versus external beam radiotherapy (EBRT) ... the American Urological Association (MAAUA) Annual Meeting in ... Relative Effectiveness of Cryosurgery and External Beam Radiation ...
(Date:9/18/2014)... 2014 A novel robotic system that ... is currently being tested as part of a biomedical ... Boston with the aim of determining if the robot, ... cancer biopsies faster, more accurate, less costly, and less ... the potential to deliver prostate cancer therapies with greater ...
(Date:9/18/2014)... Texas (PRWEB) September 18, 2014 ... Chancellor John Sharp, Texas A&M Health Science Center ... U.S. Department of Health and Human Services (HHS), ... dedicated a national pandemic influenza vaccine manufacturing facility ... as an anchor for the Texas A&M Biocorridor ...
Breaking Biology Technology:EMD Serono Awards Grant for Growth Innovation (GGI) for the First Time 2EMD Serono Awards Grant for Growth Innovation (GGI) for the First Time 3HealthTronics Announces Data Comparing Cryotherapy Versus Radiation for Treating Prostate Cancer Poster Presented at the American Urological Association Regional Meeting 2Worcester Polytechnic Institute Participates in Clinical Trial for MRI-Compatible Robot Designed to Improve Accuracy of Prostate Cancer Biopsies 2Worcester Polytechnic Institute Participates in Clinical Trial for MRI-Compatible Robot Designed to Improve Accuracy of Prostate Cancer Biopsies 3Worcester Polytechnic Institute Participates in Clinical Trial for MRI-Compatible Robot Designed to Improve Accuracy of Prostate Cancer Biopsies 4Worcester Polytechnic Institute Participates in Clinical Trial for MRI-Compatible Robot Designed to Improve Accuracy of Prostate Cancer Biopsies 5Worcester Polytechnic Institute Participates in Clinical Trial for MRI-Compatible Robot Designed to Improve Accuracy of Prostate Cancer Biopsies 6Texas A&M Dedicates National Pandemic Influenza Vaccine Manufacturing Facility, on Track for 2016 Start-Up Phase 2Texas A&M Dedicates National Pandemic Influenza Vaccine Manufacturing Facility, on Track for 2016 Start-Up Phase 3Texas A&M Dedicates National Pandemic Influenza Vaccine Manufacturing Facility, on Track for 2016 Start-Up Phase 4
... -- Cingular Wireless will invest more than $300 ... Wisconsin -- including turning on-air 110 new cell sites, ... will spend $6.2 billion to enhance and expand its ... year, Cingular put into service 22 cell ...
... Attorney Joe Hildebrandt has been a part of ... some close at home and others in the financial ... the years, Hildebrandt told a legislative committee last week, ... state" that neither wants nor welcomes investors. , ,Lately, ...
... Wis. - Milton Silva-Craig has joined the board ... reported on Monday. , ,Neurognostics, which spun out of ... resonance imaging (fMRI) products and services , ,Silva-Craig is ... which he joined in March, 2001. Emageon ...
Cached Biology Technology:State's investment in early-stage businesses is changing perceptions 2State's investment in early-stage businesses is changing perceptions 3
... your protein is in solution or in a ... mass spectrometry. Proteins will be digested to produce ... of the peptides are determined by MALDI-TOF, and ... peaks (peptides) from MALDI-TOF will be determined by ...
OmniSlide Heated Wash Module. 2 independent chambers with precise temperature control from ambient of 5C to 70C. Each chamber holds 1 slide rack (20 slides). Includes 2 x Wash Sleeves, 1 x Slide R...
For cleavage of 6xHis tags from proteins containing a Factor Xa Protease recognition site Efficient 6xHis tag cleavage (greater than 90%), ...
Request Info...
Biology Products: