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Women at risk from vitamin A deficiency
Date:11/17/2009

Almost half of UK women could be suffering from a lack of vitamin A due to a previously undiscovered genetic variation, scientists at Newcastle University have found.

The team, led by Dr Georg Lietz, has shown that almost 50 per cent of women have a genetic variation which reduces their ability to produce sufficient amounts of vitamin A from beta-carotene.

Vitamin A also known as retinol plays a vital role in strengthening our immune system, protecting us against common infections such as flu and winter vomiting.

Vitamin A also helps to maintain healthy skin and mucus linings such as inside the nose and the lungs.

In 1987, an American study found that excessive use of vitamin A during pregnancy was associated with certain birth defects. Beta-carotene, however, was deemed to be safe and this led to the general advice that we should eat more of this nutrient, allowing the body to convert what it needs into vitamin A.

However, Dr Lietz' latest research published in the FASEB Journal and presented this month at the 2nd Hohenheim Nutrition Conference in Stuttgart shows that for many women, beta-carotene is not an effective substitute for vitamin A.

Dr Lietz explained: "Vitamin A is incredibly important particularly at this time of year when we are all trying to fight off the winter colds and flu.

"It boosts our immune system and reduces the risk of inflammation such as that associated with chest infections.

"What our research shows is that many women are simply not getting enough of this vital nutrient because their bodies are not able to convert the beta-carotene."

From a volunteer group of 62 women, the team found that 29 of them 47 per cent carried the genetic variation which prevented them from being able to effectively convert beta-carotene into vitamin A.

The study also showed that all volunteers consumed only about a third of their recommended intake from 'preformed' vitamin
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Contact: Dr. Georg Lietz
georg.lietz@ncl.ac.uk
44-191-222-6893
Newcastle University
Source:Eurekalert

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