Navigation Links
Women at risk from vitamin A deficiency
Date:11/17/2009

Almost half of UK women could be suffering from a lack of vitamin A due to a previously undiscovered genetic variation, scientists at Newcastle University have found.

The team, led by Dr Georg Lietz, has shown that almost 50 per cent of women have a genetic variation which reduces their ability to produce sufficient amounts of vitamin A from beta-carotene.

Vitamin A also known as retinol plays a vital role in strengthening our immune system, protecting us against common infections such as flu and winter vomiting.

Vitamin A also helps to maintain healthy skin and mucus linings such as inside the nose and the lungs.

In 1987, an American study found that excessive use of vitamin A during pregnancy was associated with certain birth defects. Beta-carotene, however, was deemed to be safe and this led to the general advice that we should eat more of this nutrient, allowing the body to convert what it needs into vitamin A.

However, Dr Lietz' latest research published in the FASEB Journal and presented this month at the 2nd Hohenheim Nutrition Conference in Stuttgart shows that for many women, beta-carotene is not an effective substitute for vitamin A.

Dr Lietz explained: "Vitamin A is incredibly important particularly at this time of year when we are all trying to fight off the winter colds and flu.

"It boosts our immune system and reduces the risk of inflammation such as that associated with chest infections.

"What our research shows is that many women are simply not getting enough of this vital nutrient because their bodies are not able to convert the beta-carotene."

From a volunteer group of 62 women, the team found that 29 of them 47 per cent carried the genetic variation which prevented them from being able to effectively convert beta-carotene into vitamin A.

The study also showed that all volunteers consumed only about a third of their recommended intake from 'preformed' vitamin A the form found in dairy products such as eggs and milk indicating that those volunteers carrying the genetic variation were not eating enough vitamin A-rich foods to reach the optimum level their body required to function.

"Worryingly, younger women are at particular risk," explained Dr Lietz, who is based in the School of Agriculture, Food and Rural Development at Newcastle University.

"The older generations tend to eat more eggs, milk and liver which are naturally rich in vitamin A whereas the health-conscious youngsters on low-fat diets are relying heavily on the beta-carotene form of the nutrient."

The next step in the study is to assess whether the effect of the genetic variation can also be observed in men and whether our body composition will influence our ability to absorb and convert beta-carotene into vitamin A.


'/>"/>

Contact: Dr. Georg Lietz
georg.lietz@ncl.ac.uk
44-191-222-6893
Newcastle University
Source:Eurekalert

Related biology news :

1. Drug could improve pregnancy outcomes in wider range of women with insulin resistance
2. Women more depressed and men more impulsive with reduced serotonin functioning
3. Pregnant women at risk for unnecessary operations due to misdiagnosis of appendicitis
4. Cell response to stress signals predicts tumors in women with common pre-breast cancer
5. Too few women scientists achieving academic leadership positions
6. Gender roles and not gender bias hold back women scientists
7. Women with AIDS face cervical cancer threat
8. New folic acid seal helps women choose enriched grain foods to help prevent birth defects
9. Do attractive women want it all?
10. Womens health-related scientific findings presented by University of Pittsburgh researchers
11. Journal of Womens Health named official journal of American Medical Womens Association
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/3/2016)... LONDON , June 3, 2016 /PRNewswire/ ... Transport Management) von Nepal ... ,Angebot und Lieferung hochsicherer geprägter Kennzeichen, einschließlich ... weltweit führend in der Produktion und Implementierung ... an der Ausschreibung im Januar teilgenommen, aber ...
(Date:6/2/2016)... 2, 2016 Perimeter Surveillance & ... Systems, Physical Infrastructure, Support & Other Service  ... offers comprehensive analysis of the global Border ... generate revenues of $17.98 billion in 2016. ... a leader in software and hardware technologies for advanced ...
(Date:5/20/2016)... May 20, 2016  VoiceIt is excited to ... VoicePass. By working together, VoiceIt and ... VoiceIt and VoicePass take slightly different approaches to ... both security and usability. ... this new partnership. "This marketing and ...
Breaking Biology News(10 mins):
(Date:6/27/2016)... 2016  Liquid Biotech USA ... a Sponsored Research Agreement with The University of ... from cancer patients.  The funding will be used ... with clinical outcomes in cancer patients undergoing a ... be employed to support the design of a ...
(Date:6/24/2016)... , June 24, 2016 Epic ... sensitively detects cancers susceptible to PARP inhibitors by ... tumor cells (CTCs). The new test has already ... therapeutics in multiple cancer types. Over ... DNA damage response pathways, including PARP, ATM, ATR, ...
(Date:6/23/2016)... ... June 23, 2016 , ... ... its second eBook, “Clinical Trials Patient Recruitment and Retention Tips.” Partnering with experienced ... this eBook by providing practical tips, tools, and strategies for clinical researchers. , ...
(Date:6/23/2016)... 23, 2016 /PRNewswire/ - FACIT has announced the ... biotechnology company, Propellon Therapeutics Inc. ("Propellon" or ... of a portfolio of first-in-class WDR5 inhibitors for ... as WDR5 represent an exciting class of therapies, ... medicine for cancer patients. Substantial advances have been ...
Breaking Biology Technology: