Navigation Links
With sinus study, Saint Louis University researchers find that harmless members of microbiome spark immune reaction
Date:12/19/2013

ST. LOUIS Saint Louis University researchers have analyzed the microbiomes of people with chronic rhinosinusitis and healthy volunteers and found evidence that some chronic sinus issues may be the result of inflammation triggered by an immune response to otherwise harmless microorganisms in the sinus membranes.

The findings, recently published in JAMA Otolaryngology - Head & Neck Surgery, support mounting evidence that inflammation may be the cause of most chronic rhinosinusitis (CRS) instead of bacterial infection.

Study author Rajeev Aurora, Ph.D., professor of molecular microbiology and immunology at Saint Louis University, says that the paper sheds new light on the spectra of microorganisms that live in our bodies and our own immune response to those organisms.

Chronic rhinosinusitis, the inflammation of the sinus and nasal passages lasting more than three months, is one of the most common chronic conditions in the U.S.

The condition can be challenging for doctors to treat because the underlying mechanisms causing the condition are not well understood. While antibiotics can help some patients, others are not helped by drugs or more invasive treatments, such as surgery to open up sinuses. Doctors have proposed any number of causes, included allergy, immune deficiency, cystic fibrosis, gastroesophageal reflux, and structural abnormalities, but questions remain about the origin of the condition.

As scientists are learning more about the body's microbiome, the specific colonies of microorganisms like bacteria that live in various places in the body, including the mouth, the intestinal tract, and skin, they are becoming aware that the clusters of microbiota can be remarkably different from each other from place to place in the same person, as well as from the microbiota of other people.

Aurora and his research team decided to study the microorganisms that live in the sinus membrane to learn more
'/>"/>

Contact: Carrie Bebermeyer
bebermcl@slu.edu
314-977-8015
Saint Louis University
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Sinusitis linked to microbial diversity
2. A solution to sinusitis from the sea
3. With new study, aquatic comb jelly floats into new evolutionary position
4. From scourge to saint: E. coli bacteria becomes a factory - to make cheaper, faster pharmaceuticals
5. Vitamin D holds promise in battling a deadly breast cancer, Saint Louis University researchers say
6. In a fight to the finish, Saint Louis University research aims knockout punch at hepatitis B
7. Saint Louis University, University of Toronto biologists help decode turtle genome
8. Saint Louis University researchers discover a way to detect new viruses
9. Research by Saint Louis University scientists offers way to disrupt fibrosis
10. BP Deepwater Horizon oil spill exacerbated existing environmental problems in Louisiana marshes
11. SMU professor Louis Jacobs honored with prestigious award from Texas science teachers
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
With sinus study, Saint Louis University researchers find that harmless members of microbiome spark immune reaction
(Date:7/22/2014)... 2014) New research from the Monell Center reveals ... can increase airway inflammation in asthmatics for at least ... that expectations can play in health-related outcomes. , "Asthmatics ... expect that an odor is harmful, our bodies react ... lead author Cristina Jan, PhD, a Monell physiologist. "Both ...
(Date:7/22/2014)... be good for the average steak, but it seems ... to survive Alaska,s winter cold. , "Alaska wood frogs ... steak does in your freezer and the frog comes ... than the steak," said Don Larson, University of Alaska ... paper demonstrating that freeze tolerance in Alaska wood frogs ...
(Date:7/22/2014)... to dust mites (and chances are you are), help ... University of Iowa have developed a vaccine that can ... response. In animal tests, the nano-sized vaccine package lowered ... the allergens, according to the paper, published in the ... Journal . One big reason why it works, the ...
Breaking Biology News(10 mins):In asthma, it's not just what you smell, but what you think you smell 2In asthma, it's not just what you smell, but what you think you smell 3Alaska frogs reach record lows in extreme temperature survival 2Alaska frogs reach record lows in extreme temperature survival 3Researchers create vaccine for dust-mite allergies 2
... (Boston) A new study from Boston University School ... pluripotent stem (iPS) cells in an experimental model were ... The study, published online in Cell Stem Cell ... develop cell types that could offer treatment for a ...
... new study that provides surprising details on changes in Earth,s ... last interglacial--the period between "ice ages"--was warmer than previously thought ... greenhouse gases increase in the atmosphere and global temperatures rise. ... the massive West Antarctic ice sheet may have contributed more ...
... led by Associate Professor Kenji Osafune and his colleague ... and Application (CiRA), Kyoto University in Japan, has succeeded ... induced pluripotent stem (iPS) cells to differentiate into intermediate ... lineages. This represents a major step toward realizing renal ...
Cached Biology News:BUSM study shows potential of differentiated iPS cells in cell therapy without immune rejection 2Analysis of Greenland ice cores adds to historical record and provide glimpse into climate's future 2Analysis of Greenland ice cores adds to historical record and provide glimpse into climate's future 3Analysis of Greenland ice cores adds to historical record and provide glimpse into climate's future 4Monitoring and robust induction of nephrogenic intermediate mesoderm from human iPSCs 2
(Date:7/22/2014)... (PRWEB) July 22, 2014 OHAUS ... portable, and mechanical balances and scales, proudly announces ... has won Laboratory Equipment magazine’s 2014 “Readers' Choice” ... second consecutive year the Explorer was voted the ... annual Readers’ Choice Awards celebrates “excellence in product ...
(Date:7/22/2014)... Massachusetts e SHENZHEN , ... Co., LTD, (BGI Tech), una filiale di BGI, la ... lancio mondiale di un nuovo servizio di sequenziamento dell,intero ... di Complete Genomics. Complete Genomics, molto ... tecnologie di sequenziamento proprietarie con il 99.999% di precisione ...
(Date:7/22/2014)... 22, 2014 Hussey Copper , a ... antimicrobial copper announces Pullman Regional Hospital,s conversion of ... antimicrobial solid touch surface, at a nominal cost.  This ... E-coli and other bacteria within 2 hours of exposure 1 ... bacteria and infectious diseases in its facilities. ...
(Date:7/22/2014)... , July 22, 2014  The Broad ... million from philanthropist Ted Stanley aimed ... bringing new treatments based on molecular understanding to ... The Stanley commitment – the ... largest for scientific research in general – will ...
Breaking Biology Technology:OHAUS Explorer Voted “Best Balance” in Laboratory Equipment’s 2014 Readers’ Choice Awards 2BGI Tech lancia un servizio di sequenziamento dell'intero esoma umano sulla piattaforma avanzata di Complete Genomics 2Pullman Regional Hospital changes more than 1,100 touch points to Hussey Copper's MD-Cu29 antimicrobial copper to help protect against bacteria 2Pullman Regional Hospital changes more than 1,100 touch points to Hussey Copper's MD-Cu29 antimicrobial copper to help protect against bacteria 3$650 million commitment to Stanley Center at Broad Institute aims to galvanize mental illness research 2$650 million commitment to Stanley Center at Broad Institute aims to galvanize mental illness research 3$650 million commitment to Stanley Center at Broad Institute aims to galvanize mental illness research 4$650 million commitment to Stanley Center at Broad Institute aims to galvanize mental illness research 5$650 million commitment to Stanley Center at Broad Institute aims to galvanize mental illness research 6$650 million commitment to Stanley Center at Broad Institute aims to galvanize mental illness research 7$650 million commitment to Stanley Center at Broad Institute aims to galvanize mental illness research 8$650 million commitment to Stanley Center at Broad Institute aims to galvanize mental illness research 9$650 million commitment to Stanley Center at Broad Institute aims to galvanize mental illness research 10
... 2011 Nile Therapeutics, Inc. (OTCQB: NLTX), a biopharmaceutical ... today announced its third quarter financial results for 2011. ... Nile reported research and development collaboration income relating to ... to none in the third quarter of 2010. The ...
... 13, 2011 Pharmasset, Inc. (Nasdaq: VRUS ) ... 8th Annual Healthcare Conference to be held November 15 to ... Pharmasset,s President and Chief Executive Officer, will provide an overview ... (ET). To access a simultaneous webcast of Mr. ...
... 2011 Spherix Incorporated (NASDAQ: SPEX ) ... metabolic syndrome and atherosclerosis, and providers of technical and ... companies -- today reported financial results for the three ... Recent and Upcoming Highlights ...
Cached Biology Technology:Nile Therapeutics Reports 2011 Third Quarter Financial Results 2Nile Therapeutics Reports 2011 Third Quarter Financial Results 3Nile Therapeutics Reports 2011 Third Quarter Financial Results 4Nile Therapeutics Reports 2011 Third Quarter Financial Results 5Pharmasset to Present at the Lazard Capital Markets Healthcare Conference 2Pharmasset to Present at the Lazard Capital Markets Healthcare Conference 3Spherix Announces Third Quarter Financial Results 2Spherix Announces Third Quarter Financial Results 3Spherix Announces Third Quarter Financial Results 4Spherix Announces Third Quarter Financial Results 5Spherix Announces Third Quarter Financial Results 6Spherix Announces Third Quarter Financial Results 7
Mouse monoclonal antibody raised against a partial recombinant ST3GAL2. NCBI Entrez Gene ID = ST3GAL2...
... an evolutionarily conserved form of cell suicide, ... The central component of this process is ... These enzymes participate in a series ... to pro-apoptotic signals and result in the ...
... DNA Visualizer Extraction Kit is manufactured for ... DNA damage byexposure to UV light. The ... is often used for DNA-cloning work. The ... bromide and exposure of UV light damages ...
...
Biology Products: