Navigation Links
Wiley Prize in Biomedical Sciences awarded to Rosbash, Hall and Young
Date:1/31/2013

The 12th annual Wiley Prize in Biomedical Sciences has been awarded to Brandeis professors Michael Rosbash and Jeffrey Hall and their colleague Michael Young of Rockefeller University for the discovery of the molecular mechanisms governing circadian rhythms.

"The molecular network discovered by these researchers imparts cyclic behavior to many biological processes including sleep and wakefulness, metabolism and even the response to drugs," said Professor Gnter Blobel, chairman of the awards jury for the Wiley Prize and a 1999 Nobel Prize winner.

Their research could ultimately lead to the development of drugs to treat sleep disorders, physical and mental illness, and even jet lag.

Five previous Wiley Prize winners have gone on to win the Nobel Prize in either physiology or medicine.

Rosbash and Hall spent more than three decades at Brandeis collaboratively researching circadian rhythms, the biological clock which governs functions such as sleep and wakefulness, metabolism and hormone levels in organisms as simple as fruit flies and as complex as humans.

"We were incredibly fortunate to have advanced this problem in the remarkable way things have turned out," says Rosbash. "Jeff and I, as well as Mike Young at Rockefeller, began these studies in the fruit fly with no certainty in my case, no expectation that the fly clockworks would be essentially identical in humans. So our work not only turned out to be interesting but also potentially important. How lucky can three guys get?"

Their research uses the fruit fly Drosophila, a model organism valued for almost a century because of its relative genetic simplicity and its wide range of behaviors. At the molecular level, circadian rhythms use the same genes and are regulated in much the same way in all animals, including humans. Rosbash and Hall cloned the first Drosophila circadian clock gene in 1984.

"The discoveries they made in terms of identifying the first circadian clock genes is really a landmark in understanding how genes regulate behavior, and understanding our own 24-hour rhythms that seem to regulate so much of our biology," says Ravi Allada, professor and chair of the Department of Neurobiology at Northwestern University, who worked in the Rosbash Lab from 1995 to 2000.

Amita Sehgal, the John Herr Musser Professor of Neuroscience at the University of Pennsylvania and an investigator with the Howard Hughes Medical Institute, said the trio's groundbreaking research "opened up the whole field of circadian rhythms and inspired people like me to go into it."

"I'm really glad that they're getting recognized for it. It's a tremendous honor for them, but also for the field," said Sehgal, who worked as a post-doc in Young's lab at Rockefeller.

The Wiley Prize in Biomedical Sciences has recognized work that opens new fields of research or advanced novel concepts or their applications in a particular biomedical discipline.

This year's award will be presented to Rosbash, Hall and Dr. Young on April 5 at Rockefeller University in New York City.


'/>"/>

Contact: Susan Chaityn Lebovits
lebovits@brandies.edu
781-736-4027
Brandeis University
Source:Eurekalert  

Related biology news :

1. Physiological societies partner with Wiley on new open access journal
2. Wiley Partners with TED
3. British Ecological Society partners with Wiley open access journal Ecology and Evolution
4. Wiley signs collaboration agreement with the Asian Federation of Biotechnology
5. Wiley launches new interdisciplinary review WIREs Energy and Environment
6. Wiley-Blackwell launches new open-access journal: Food Science & Nutrition
7. WileyChina.com - Now Featuring Bespoke Pages for China’s Life Scientists
8. Israel Prize awarded to Tel Aviv University biochemist
9. Brupbacher Prize goes to cancer researcher Michael Karin
10. 2 climate scientists win 2012 Vetlesen Prize for work on ozone hole, ice cores
11. Leibniz Prizes 2013: DFG honors 11 outstanding researchers
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Wiley Prize in Biomedical Sciences awarded to Rosbash, Hall and Young
(Date:3/18/2016)... LONDON , March 18, 2016 ... Established Suppliers of Biometrics, ICT, Manned & Unmanned Vehicles, Physical ... & security companies in the border security market and ... and Europe has led ... your companies improved success. --> defence & ...
(Date:3/14/2016)... Allemagne, March 14, 2016 ... - --> - Renvoi : image disponible ... --> --> DERMALOG, ... fournit de nouveaux lecteurs d,empreintes digitales pour l,enregistrement ... DERMALOG sera utilisé pour produire des cartes d,identité ...
(Date:3/9/2016)... , March 9, 2016 This BCC ... future states of the RNA Sequencing (RNA Seq) market ... such as instruments, tools and reagents, data analysis, and ... various segments of the RNA-Sequencing market such as RNA-Sequencing ... Identify the main factors affecting each segment and forecast ...
Breaking Biology News(10 mins):
(Date:4/27/2016)... MedDay, a biotechnology company focused on the treatment ... Moukheibir as Chairman of its Board of Directors. ... , who contributed to the rapid development of the Company ... started her career in strategy consulting and investment banking in ... .  She held C-Suite level roles in some of ...
(Date:4/26/2016)... ... April 26, 2016 , ... ... that Ardy Arianpour has joined the company as Chief Business Officer. Arianpour, a ... innovative genomic technologies to market, was most recently Chief Commercial Officer of Pathway ...
(Date:4/26/2016)... ... 2016 , ... Mr. Palmer created the RPO business for Ceridian and lead ... managed services contract in the U.S. intelligence community with The SI (a Lockheed Martin ... Younger, founder of Accolo. “We are growing and his experience guiding our expansion ...
(Date:4/26/2016)... Washington (PRWEB) , ... April 26, 2016 , ... ... today announced receipt of a significant operating grant from 1Plus12 Corporation. The grant ... to commence pre-proposal activities as outlined on the organization's website http://www.ivsci.org ...
Breaking Biology Technology: