Navigation Links
Why serotonin can cause depression and anxiety
Date:2/4/2008

Mood disorders could be caused by a loss of our inherent, reflexive avoidance of aversive events, according to a study published in PLoS Computational Biology. Researchers from UCL in London and Columbia University in New York used computational modeling techniques to integrate what appeared to be blatant contradictions between serotonins roles in different states of health.

Serotonin appears to be one of the major players in mood and a variety of other disorders. But exactly how remains an open question. Imagine walking past a dark alleyway in a dangerous part of some city; although it might be a shortcut, most people wouldnt consider taking it. In healthy subjects, serotonin appears important for this automatic avoidance.

It has long been suggested that over-activity of the serotonin system may relate to mood disorders such as depression and anxiety, as these seem characterized by too much withdrawal and avoidance. However, the new modeling study simply suggests that we think about what happens when these reflexes failsuddenly you have to think hard to avoid things that used to be avoided reflexively You might for example consider walking down the dangerous alley, be robbed and thus be reminded and taught by additional experience that dark alleys are to be avoided.

In this study Prof. Peter Dayan and Dr. Quentin Huys built a reinforcement learning model of reflexive choices. Agents take actions and as a result of these move through a set of states, some of which are rewarded or punished. As agents progress through this space, they learn the value of each statehow much punishment or reward is to be expected from this state onwards.

It turns out that adding to the agents behavioural repertoire a simple reflex, which guides the agent away from an action with potential for poor consequences, does two things: it increases the rewards reaped overall, but, because bad states are now not explored any more, it also preven
'/>"/>

Contact: Mary Kohut
Press@plos.org
415-568-3457
Public Library of Science
Source:Eurekalert

Page: 1 2

Related biology news :

1. Women more depressed and men more impulsive with reduced serotonin functioning
2. deCODE discovers cause of major subtype of glaucoma
3. Study begins to reveal clues to the cause and progression of sepsis
4. Bleeding, not inflammation, is major cause of early lung infection death
5. Gamma globulin effective in treating eye infections caused by adenoviruses
6. Hidden interactions between predators and prey: evolution causes cryptic dynamics in ecology
7. Spaceflight shown to alter ability of bacteria to cause disease
8. Grubs passion for plastic causes water loss
9. Human embryonic stem cells remain embryonic because of epigenetic factors
10. Salmonid hatcheries cause stunning loss of reproduction
11. Researchers find evidence linking stress caused by the Sept. 11 disaster with low birth weights
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/27/2014)... vitro study has revealed that nicotine and cotinine, a ... by a certain carcinogen in smoke. , The carcinogen ... tobacco leaves and ultimately ends up in the tobacco ... and liver, where it is activated by a variety ... mice has revealed that nicotine can partially interfere with ...
(Date:7/27/2014)... climate change to cut food supplies. But these studies ... increasing temperature and air pollution specifically ozone pollution, ... study involving researchers at MIT shows that these interactions ... take both warming and air pollution into account in ... at global production of four leading food crops ...
(Date:7/25/2014)... 100,000s of people lived on the land now called ... control the availability of plants they used for food, ... fire to maintain desired habitat and natural resources. , ... Pacific Southwest Station, will lead a field trip ... the Ecological Society of America,s 99th Annual Meeting, in ...
Breaking Biology News(10 mins):Nicotine found to inhibit DNA-strand break caused by a certain carcinogen in smoke 2Study: Climate change and air pollution will combine to curb food supplies 2Study: Climate change and air pollution will combine to curb food supplies 3Fire ecology manipulation by California native cultures 2Fire ecology manipulation by California native cultures 3
... number one killer in the world and India carries more ... set to rise: it is predicted that by 2010 India,s ... Today, an international team of 25 scientists from four countries ... the world,s population carries a mutation almost guaranteed to lead ...
... of yeast cells has resulted in the most detailed ... a Texas A&M University chemical engineering professor whose findings ... until now have remained mostly theory., Working with populations ... Katy Kao, assistant professor in the Artie McFerrin Department ...
... new, international competition called the Digging into Data ... the Joint Information Systems Committee (JISC) from the ... (NEH) and the National Science Foundation (NSF) from ... Humanities Research Council (SSHRC) from Canada. ...
Cached Biology News:The heart disease mutation carried by 60 million 2Evolutionary process more detailed than previously believed, study shows 2Evolutionary process more detailed than previously believed, study shows 3Evolutionary process more detailed than previously believed, study shows 4Leading research agencies announce new international competition: "The digging into data challenge" 2
(Date:7/28/2014)... MD (PRWEB) July 28, 2014 ... personalized medicine, will be exhibiting data and research conducted ... International Spine Intervention Society’s (ISIS) 22nd Annual ... 3rd, at the Hyatt Regency, in Orlando, Florida. ... knowledge and clinical competence of physicians who care for ...
(Date:7/28/2014)... , July 28, 2014  David Hardison, Ph.D., ... by Deloitte , has been elected chairman of ... Consortium, a non-profit working to establish common protocols ... as it relates to electronic health records. ... mission of collaborating with organizations across the research ...
(Date:7/28/2014)... 28, 2014 It’s a hard truth: Nearly ... to further their post-secondary education are failing to obtain a ... this year. And according to an analysis by The ... veteran students’ uninformed choice of college majors, which leads to ... the study: Some 51.7 percent of post-9/11 veterans using ...
(Date:7/28/2014)... July 28, 2014 Research and Markets ... Analysis Market 2014-2018" report to their offering. ... analysis is a technique used to determine the size of ... It is crucial to analyze the size of particles as ... size analysis is performed to determine the behavior and nature ...
Breaking Biology Technology:Proove Biosciences Exhibits Industry Leading Data and Research at International Spine Intervention Society’s 22nd Annual Scientific Meeting 2ConvergeHEALTH by Deloitte's David Hardison Named Chairman of the Clinical Data Interchange Standards Consortium 2ConvergeHEALTH by Deloitte's David Hardison Named Chairman of the Clinical Data Interchange Standards Consortium 3Resume Place: To Choose the Best College Majors, Veterans Need Early Career Counseling, Data Shows 2Resume Place: To Choose the Best College Majors, Veterans Need Early Career Counseling, Data Shows 3Resume Place: To Choose the Best College Majors, Veterans Need Early Career Counseling, Data Shows 4Global Particle Size Analysis Market 2014-2018 2
... will visit Chicago during an eight-day multi-state, multi-agency ... grants. , , SWIFT V Tour brings ... to brief seminar participants on their agency's Small ... Transfer (STTR) programs and to discuss research topics. ...
... way through school, you studied hard to get the right ... hard to say the right thing. , ,Through your career, ... excel in your field and do the right thing at ... some Midwest high-tech workers, being right can be a big ...
... in computing performance were developed at the ... departments at the University of Wisconsin-Madison. , ,Innovations ... grid and cluster computing were some of the ... and other faculty last Wednesday at Accelerate Madisons ...
Cached Biology Technology:Federal grant seminar coming to Chicago as part of SWIFT V Tour 2How to thwart the dont-be-right Midwest technology boss 2How to thwart the dont-be-right Midwest technology boss 3How to thwart the dont-be-right Midwest technology boss 4UW computer scientists tout achievements and explain industry shortcomings 2UW computer scientists tout achievements and explain industry shortcomings 3
Request Info...
5-bromouridine 5'-triphosphate (BrUTP) *10 mM in TE buffer*...
Estrogen Receptor (ER) Competitor Assay Kits Green for Estrogen Receptors-alpha and -beta (ER-Alpha and ER-Beta) are ideal for screening novel estrogen receptor binding compounds and endocrine disrup...
Prepared in distilled water....
Biology Products: