Navigation Links
Why one way of learning is better than another
Date:10/1/2009

This release is available in French.

A new study from the Montreal Neurological Institute and Hospital (The Neuro) of McGill University reveals that different patterns of training and learning lead to different types of memory formation. The significance of the study, published in the Journal of Neuroscience, is that it identifies the molecular differences between spaced training (distributed over time) and massed training (at very short intervals), shedding light on brain function and guiding learning and training principles.

In every organism studied, results have shown that memory formation is highly sensitive not only to the total amount of training, but also to the pattern of trials used during training. In particular, trials distributed over time are superior at generating long-term memories than trials presented at very short intervals.

"It is a well known psychological principle that learning is better when training trials are spaced out than when given all together," says Dr. Wayne Sossin, neuroscientist at The Neuro and lead investigator of the study. "However, there are very few, if any studies that identify, at the molecular level, differences between the two types of training."

"In this study, using Aplysia, a type of mollusk often used as a model of learning in which the difference between spaced and massed training has been well established, we identify an event, the activation of the enzyme called Protein kinase C Apl II (PKC Apl II), which is very different under the two training paradigms and could explain the differences in learning.

The process of strengthening communication between nerve cells (neurons), called synaptic facilitation, represents learning and is the basis of change in learning in Aplysia. This process is controlled by the release of a neurotransmitter called serotonin. Four to five spaced applications of serotonin generate long-term changes in the strength of the synapse the junction between two neurons - but in this study lead to less activation of PKC Apl II. This leads to stronger connections between neurons and therefore increased learning and memory. In contrast, if the application of serotonin is continuous, as would be the case in massed learning/training, the researchers found that there was much more activation of PKC Apl II, suggesting that activation of this enzyme may block the mechanisms for generating long-term memory, while retaining mechanisms for short-term memory.

This study shows that the enzyme PKC Apl II is regulated differently by spaced versus massed applications of serotonin and that the difference in activation of PKC Apl II can explain some of the distinction between spaced and massed training.


'/>"/>

Contact: Anita Kar
anita.kar@mcgill.ca
514-398-3376
McGill University
Source:Eurekalert

Related biology news :

1. Scientists devise efficient way of learning about complex corn traits
2. Scientists are learning more about big birds from feathers
3. MU study finds connection between evolution, classroom learning
4. Learning how the pieces responsible for interpreting the human genome work
5. At WPI, some students are learning its OK to peek
6. DREAM: 1 gene regulates pain, learning and memory
7. New report on science learning at museums, zoos, other informal settings
8. Baby talk: The roots of the early vocabulary in infants learning from speech
9. Moths with a nose for learning
10. Relearning process not always a free lunch
11. Statin does not appear helpful for children with learning disabilities caused by genetic disorder
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/2/2016)... LONDON , June 2, 2016 ... has awarded the 44 million US Dollar project, ... Security Embossed Vehicle Plates including Personalization, Enrolment, and IT Infrastructure ... world leader in the production and implementation of Identity Management ... in January, however Decatur was selected ...
(Date:5/20/2016)... , May 20, 2016  VoiceIt is excited ... with VoicePass. By working together, VoiceIt ...  Because VoiceIt and VoicePass take slightly different approaches ... increases both security and usability. ... about this new partnership. "This marketing ...
(Date:4/28/2016)... BANGALORE, India , April 28, 2016 ... subsidiary of Infosys (NYSE: INFY ), and Samsung ... global partnership that will provide end customers with a ... and payment services.      (Logo: http://photos.prnewswire.com/prnh/20130122/589162 ... for financial services, but it also plays a fundamental part ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... June 23, 2016 A person commits a crime, ... scene to track the criminal down. An outbreak ... and Drug Administration (FDA) uses DNA evidence to track down ... Sound far-fetched? It,s not. The FDA has increasingly used ... investigations of foodborne illnesses. Put as simply as possible, whole ...
(Date:6/23/2016)... -- The Biodesign Challenge (BDC), a university competition that asks ... systems and biotechnology, announced its winning teams at the ... York City . The teams, chosen ... MoMA,s Celeste Bartos Theater during the daylong summit. Keynote ... of architecture and design, and Suzanne Lee , ...
(Date:6/23/2016)... ... June 23, 2016 , ... In a new case report published ... how a patient who developed lymphedema after being treated for breast cancer benefitted from ... the paradigm for dealing with this debilitating, frequent side effect of cancer treatment. ...
(Date:6/23/2016)... , June 23, 2016 On Wednesday, ... at 4,833.32, down 0.22%; the Dow Jones Industrial Average edged ... closed at 2,085.45, down 0.17%. Stock-Callers.com has initiated coverage on ... ), Nektar Therapeutics (NASDAQ: NKTR ), Aralez Pharmaceuticals ... (NASDAQ: BIND ). Learn more about these stocks ...
Breaking Biology Technology: