Navigation Links
Why metastasic cells migrate
Date:3/29/2010

activated are migratory and invasive", says Martin-Blanco. "If we block the signal of Dpp in the cells, they stop moving. However, if the Dpp protein is over expressed, cells have even more and enhanced migratory and invasive capacities.

The authors have worked with embryos of the fly Drosophila melanogaster, during the formation of its abdominal epithelium, in metamorphosis. This is a process where histoblasts (embryonic cells) that will form the fly abdomen replace larval epidermal cells. The histoblasts remain at the beginning in small nests or groups of cells, and they progressively multiply, spreading and invading the space to substitute all larval epithelial cells.

This is the most clear example that scientists have seen this gene family (Dpp, BMP and TGFβ) playing the role of controlling mobility and invasiveness in normal cells. Martin-Blanco adds that "now we can study this mechanism in healthy cells, and we hope to discover more about the conditions that can inhibit or accelerate it." They expect not only to understand better this mechanism but also to find alternative strategies to inhibit metastasis.


'/>"/>

Contact: Ainhoa Goi
g.prensa@csic.es
0034-915-681-472
CSIC, Consejo Superior de Investigaciones Cientficas
Source:Eurekalert

Page: 1 2

Related biology news :

1. ESF EURYI award winner aims to stop cancer cells reading their own DNA
2. Newly created cancer stem cells could aid breast cancer research
3. AIDS interferes with stem cells in the brain
4. Clemson scientists shed light on molecules in living cells
5. Social habits of cells may hold key to fighting diseases
6. UF scientists reveal how dietary restriction cleans cells
7. Human derived stem cells can repair rat hearts damaged by heart attack
8. Scientists identify embryonic stem cells by appearance alone
9. Cells united against cancer
10. Pittsburgh scientists identify human source of stem cells with potential to repair muscle
11. U of M begins nations first clinical trial using T-reg cells from cord blood in leukemia treatment
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/9/2015)... JOSE, Calif. , April 9, 2015 ... human interface solutions, announced today that it will report ... on Thursday, April 23, 2015, after the close of ... for analysts and investors at 2:00 p.m. PT (5:00 ...   To participate on the live call, ...
(Date:4/2/2015)... -- According to preliminary estimates Fingerprint Cards, ... than 125 MSEK. This exceeds the guidance provided by ... for Q1 2015 would be in line with the ... The operating result for the first quarter is estimated ... will as previously communicated be published on May 21. ...
(Date:3/31/2015)... YORK , March 31, 2015   Guidepoint ... the launch of the Post-Surgical Pain Management TRACKER, part ... products tracking usage trends in the medical device and ... access to data including treatment volumes, market share, and ... the pain associated with joint surgery. The ...
Breaking Biology News(10 mins):Synaptics to Report Third Quarter Results on April 23 2Fingerprint Cards Revises Revenues for Q1 2015 2Guidepoint Launches Post-Surgical Pain Management TRACKER 2Guidepoint Launches Post-Surgical Pain Management TRACKER 3
... a negative view of climate engineering, the deliberate large-scale ... to a new study. The results are from ... (New Zealand) who have undertaken the first systematic large-scale ... The work is published in Nature Climate ...
... announced today the purchase of an Irys ™ System ... genome assembly of Aegilops tauschii, one of three progenitors ... led by Dr. Jan Dvorak , will use the Irys ... orientation of all genes and transposable elements of the A. ...
... of Nottingham have discovered a key difference in the biological ... bacterial pathogens. The study, published in the journal ... the University,s School of Life Sciences, centred on STAT1, a ... role in regulating genes in the body. STAT-1 responds ...
Cached Biology News:Climate engineering -- what do the public think? 2UC Davis Purchases Irys System From BioNano Genomics To Advance Genome Mapping And Assembly Of Wheat Relative 2UC Davis Purchases Irys System From BioNano Genomics To Advance Genome Mapping And Assembly Of Wheat Relative 3UC Davis Purchases Irys System From BioNano Genomics To Advance Genome Mapping And Assembly Of Wheat Relative 4UC Davis Purchases Irys System From BioNano Genomics To Advance Genome Mapping And Assembly Of Wheat Relative 5Research uncovers key difference between our bodies' fight against viruses and bacteria 2
(Date:5/4/2015)... Marianjoy Rehabilitation Hospital has ... hand impairments by acquiring the Armeo®Spring arm and ... site. , Secured through grant support of a ... option for patients with upper extremity weakness or ... of just four Illinois providers offering treatment with ...
(Date:5/1/2015)... , May 1, 2015 /CNW/ - Softchoice, a leading North American ... is the proud recipient of two Cisco® Partner Summit Country ... of the Year and Security Partner of the Year for ... taking place this week in Montreal . ... but two Cisco partner awards at this year,s conference," said ...
(Date:5/1/2015)... SILVER SPRING, Md. and RESEARCH TRIANGLE ... Corporation (NASDAQ: UTHR ) announced today that Roger ... Therapeutics, will provide an overview and update on the company,s ... Care Conference in Boston, Massachusetts . ... 2015, at 3:30 PM Eastern Time, and can be accessed ...
(Date:4/30/2015)... 30, 2015 /PRNewswire/ - BioAmber Inc. (NYSE: BIOA ... that it has commenced an underwritten public offering of ... the underwriters a 30-day option to purchase up to ... stock offered in the public offering. The offering is ... assurance as to whether or when the offering may ...
Breaking Biology Technology:Marianjoy Acquires Armeo®Spring Arm and Hand Rehabilitation Exoskeleton at Oakbrook Terrace Facility 2Softchoice recognized with two Country Awards at Cisco Partner Summit 2015 2BioAmber Inc. Announces Public Offering Of Common Stock 2BioAmber Inc. Announces Public Offering Of Common Stock 3
... Brownstein, Art Director at CONNEXION Healthcare (CXHC), ... by the Healthcare Businesswomen,s Association (HBA). HBA ... sectors of the healthcare industry, including pharmaceutical, ... market research. Nominated by HBA,s corporate members, ...
... Calif., Feb. 18 Amgen Inc. (Nasdaq: ... Drug Administration (FDA) has accepted Amgen,s submission and filed ... RANK Ligand inhibitor. The indications for which Amgen ... postmenopausal osteoporosis (PMO) in women and treatment and prevention ...
... Speed up the Peer Review Process!COLUMBIA, S.C., ... Bulletin Board: CLXS), a leading developer of ... today that the American Association for Cancer ... Finder and Journal Dashboard applications for the ...
Cached Biology Technology:Jennifer Brownstein, of CONNEXION Healthcare, Honored as 'Rising Star' by Healthcare Businesswomen's Association 2FDA Accepts Amgen's Submission and Files Biologics License Application for Denosumab 2FDA Accepts Amgen's Submission and Files Biologics License Application for Denosumab 3FDA Accepts Amgen's Submission and Files Biologics License Application for Denosumab 4FDA Accepts Amgen's Submission and Files Biologics License Application for Denosumab 5FDA Accepts Amgen's Submission and Files Biologics License Application for Denosumab 6American Association for Cancer Research (AACR) Deploys Collexis' Reviewer Finder and Journal Dashboard Applications 2American Association for Cancer Research (AACR) Deploys Collexis' Reviewer Finder and Journal Dashboard Applications 3