Navigation Links
Why fad diets work well for some, but not others
Date:7/28/2010

Ever notice some people seem to eat anything they want and never gain a pound, while others seem to gain weight just by looking at fattening foods? You may be seeing things correctly after all. According to research published in the July 2010 issue of Genetics (http://www.genetics.org), this may have a biological cause. Using fruit flies, researchers have found that genes interacting with diet, rather than diet alone, are the main cause of variation in metabolic traits, such as body weight. This helps explain why some diets work better for some people than others, and suggests that future diets should be tailored to an individual's genes rather than to physical appearance.

"There is no one-size-fits all solution to the diseases of obesity and type-2 diabetes," said Laura K. Reed, Ph.D, a researcher from the Department of Genetics at North Carolina State University, the lead investigator in the work. "Each person has a unique set of genetic and environmental factors contributing to his or her metabolic health, and as a society, we should stop looking for a panacea and start accepting that this is a complex problem that may have a different solution for each individual."

To make this discovery, the scientists studied 146 different genetic lines of fruit flies that were fed four different diets (nutritionally balanced, low calorie, high sugar, and high fat). Researchers then measured a variety of metabolic traits, including body weight, in each group. Flies in some of the genetic lines were highly sensitive to their diets, as reflected by changes in body weight, while flies of other lines showed no change in weight across diets. The scientists were able to ascertain what portion of the total variation in the metabolic traits was determined by genetics alone, by diet alone, or by the interaction between genotype and diet. Results showed that diet alone made a small contribution to the total variation, while genotype and genotype interactions with diet made very large contributions. This study strongly suggests that some individuals can achieve benefits from altering their dietary habits, while the same changes for others will have virtually no effect.

"The summer beach season often serves as a 'gut check' for many in terms of their weight," said Mark Johnston, Editor-in-Chief of the journal Genetics. "This research explains why the one-size-fits-all approach offered by many diet programs can have dramatically different effects for people who try them."


'/>"/>

Contact: Tracey DePellegrin Connelly
td2p@andrew.cmu.edu
412-268-1812
Genetics Society of America
Source:Eurekalert

Related biology news :

1. Eliminating soda from school diets does not affect overall consumption
2. Low-carb diets can affect dieters cognition skills
3. Nutrigenomics -- developing personalized diets for disease prevention
4. High-fat diets inflame fat tissue around blood vessels, contribute to heart disease
5. Doctors endorse vegan and vegetarian diets for healthy pregnancies
6. Nutrigenomics -- developing personalized diets for disease prevention -- part 2 just published in OMICS
7. Diabetics on high-fiber diets might need extra calcium, report UT Southwestern researchers
8. People of higher socioeconomic status choose better diets -- but pay more per calorie
9. ADA releases updated position paper on vegetarian diets
10. Do high-fat diets make us stupid and lazy?
11. Happy holidays from the groaning board; Western diets turn on fat genes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/18/2016)... JOSE, Calif. , Jan. 18, 2016 /PRNewswire/ ... security software that simplifies the use and access ... technology and go-to-market partnership with American Cyber.  ... Cyber brings extensive experience leading transformational C4ISR and ... implementing and integrating the latest proven technology solutions," ...
(Date:1/13/2016)... ALBANY, New York , January 13, 2016 /PRNewswire/ ... Transparency Market Research has published a new market report ... Share, Growth, Trends, and Forecast, 2015 - 2023. According to ... mn in 2014 and is anticipated to reach US$1,625.8 ... from 2015 to 2023. In terms of volume, the ...
(Date:1/11/2016)... , Jan. 11, 2016 Synaptics Incorporated ... interface solutions, today announced that its ClearPad ® ... (TDDI) products won two separate categories in the 8 ... Innovator and Best Technology Breakthrough. The Synaptics ® ... a simplified supply chain, thinner devices, brighter displays and ...
Breaking Biology News(10 mins):
(Date:2/12/2016)... , Feb. 12, 2016  PTC Therapeutics, Inc. ... annual STRIVE (Strategies to Realize Innovation, Vision and ... (DMD). STRIVE provides funds to patient advocacy organizations ... make meaningful contributions to the rare disease community ... of future patient advocates. Mary ...
(Date:2/11/2016)... NBIX ) today announced its financial results for the quarter ... --> For the fourth quarter of 2015, the ... per share, compared to a net loss of $19.4 million, or ... the year ended December 31, 2015, the Company reported a net ... to a net loss of $60.5 million, or $0.81 loss per ...
(Date:2/11/2016)... , Feb. 11, 2016  Bioethics International, a not-for-profit organization ... researched, developed, marketed and made accessible to patients around the ... had named the publication of the Good Pharma ... publication is also featured as one of BMJ Open ... last year that are most frequently read. Ed ...
(Date:2/11/2016)... (PRWEB) , ... February 11, ... ... business-to-business publication dedicated to delivering cutting-edge information focused on the development and ... Sciences to become a premier sponsor of the 2016 BioProcess International Awards ...
Breaking Biology Technology: