Navigation Links
Why astronauts experience low blood pressure after returning to Earth from space
Date:10/25/2012

Bethesda, MDWhen astronauts return to Earth, their altitude isn't the only thing that dropstheir blood pressure does too. This condition, known as orthostatic hypotension, occurs in up to half of those astronauts on short-term missions (two weeks or less) and in nearly all astronauts after long-term missions (four to six months). A new research report published online in The FASEB Journal (http://www.fasebj.org) solves the biological mystery of how this happens by showing that low gravity compromises the ability of arteries and veins to constrict normally, inhibiting the proper flow of blood. Prevention and treatment strategies developed for astronauts may also hold promise for elderly populations on Earth who experience orthostatic hypotension more than any other age group.

"The idea of space exploration has been tantalizing the imagination of humans since our early existence. As a scientist, I have had the opportunity to learn that there are many medical challenges associated with travel in a weightless environment, such as orthostatic hypotension, bone loss and the recently recognized visual impairment that occurs in astronauts," said Michael D. Delp, Ph.D., a researcher involved in the work from the Department of Applied Physiology and Kinesiology, and the Center for Exercise Science at the University of Florida in Gainesville, Florida. "Although I have come to realize that it is unlikely I will ever get to fulfill my childhood dream of flying in space, I take great satisfaction with helping in the discovery of how microgravity alters the human body and how we can minimize these effects, so humans can safely explore the bounds of our universe."

To make this discovery, Delp and colleagues examined arteries and veins from mice housed at Kennedy Space Center in Florida with blood vessels from groups of mice flown on three of the last five space shuttle missionsSTS-131, STS-133 and STS-135. Mice flown on the STS-131 and STS-135 missions were tested immediately after returning to Earth, whereas mice from STS-133 were tested one, five and seven days after landing. Not only did they find that these mice experienced the equivalent of orthostatic hypotension in humans, they also discovered that it takes as many as four days in normal gravity before the condition is reversed.

"There has been considerable interest in sending humans to the moon, asteroids, and Mars," said Gerald Weissmann, M.D., Editor-in-Chief of The FASEB Journal, "but what we're finding is that extended space missions have their own inherent risks above and beyond the obvious. If we ever hope to visit distant worlds for extended periods of timeor colonize them permanentlywe've got to figure out how to mitigate the effects that low and no gravity has on the body. This report brings us an important step closer to doing just that."


'/>"/>
Contact: Cody Mooneyhan
cmooneyhan@faseb.org
301-634-7104
Federation of American Societies for Experimental Biology
Source:Eurekalert

Related biology news :

1. Scientists discover enzyme that could slow part of the aging process in astronauts -- and the elderly
2. World experts meet in Edinburgh to consider how life experiences impact on our genes
3. Validity CTO to Present Natural ID Solutions for Improving Mobile Risk Management and User Experience at NFC Solutions Summit 2012
4. Awake mental replay of past experiences critical for learning
5. African Americans less likely to adhere to DASH diet for lowering blood pressure
6. Einstein researcher receives $10.8 million grant to study toxic blood reactions caused by hemoglobin
7. Aging kidneys may hold key to new high blood pressure therapies
8. Nanoparticles reboot blood flow in brain
9. New technology to transform blood processing
10. Danger in the blood: U-M scientists show how antibiotic-resisting bacterial infections may form
11. Embryonic blood vessels that make blood stem cells can also make beating heart muscles
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/11/2017)... 11, 2017 Crossmatch®, a globally-recognized leader ... today announced that it has been awarded a ... Activity (IARPA) to develop next-generation Presentation Attack Detection ... "Innovation has been a driving force within Crossmatch ... allow us to innovate and develop new technologies ...
(Date:4/11/2017)... N.Y. , April 11, 2017 ... fingerprints, but researchers at the New York University ... College of Engineering have found that partial similarities ... security systems used in mobile phones and other ... thought. The vulnerability lies in the ...
(Date:4/6/2017)... Forecasts by Product Type (EAC), Biometrics, Card-Based ... & Logistics, Government & Public Sector, Utilities / Energy ... Nuclear Power), Industrial, Retail, Business Organisation (BFSI), Hospitality & ... for a definitive report on the $27.9bn Access Control ... ...
Breaking Biology News(10 mins):
(Date:7/13/2017)... Maryalnd (PRWEB) , ... July 13, 2017 , ... ... Innovative Technology Center, Inc. (FITCI), has experienced robust growth in the past year ... public/private nonprofit has launched several Entrepreneurial Acceleration Programs and expanded its board of ...
(Date:7/13/2017)... WA (PRWEB) , ... July 13, 2017 , ... ... machine vision solutions for life sciences, will demonstrate advancements of the MicroHAWK platform for ... systems – from Booth #4456 at the AACC Clinical Lab Expo, taking place on ...
(Date:7/12/2017)... ... July 12, 2017 , ... Dr. Julia Oh, a highly respected ... of a Microbiome Impact Grant from uBiome, the leading microbial genomics company. Dr. Oh ... in the transmission of pathogens between elderly people in geriatric communities. , The ...
(Date:7/11/2017)... ... ... The Pittcon Exposition Committee is now accepting booth space reservations for Pittcon 2018, ... for a standard 10’ x 10’ space is available to all exhibitors until September ... wish to be included in the first round of booth assignments should have their ...
Breaking Biology Technology: