Navigation Links
Why a common treatment for prostate cancer ultimately fails
Date:8/21/2008

the body changes from situation to situation. Like a foreman turning to a pool of employees to get certain jobs done, the androgen receptor taps different molecules in different situations, forming intricate complexes or groupings that then accomplish various tasks. The receptor works very quickly, assembling a team within seconds, accomplishing a task, then disbanding and making its helpers available to form a brand new team for another task.

Chang's team is working on ways to focus on these molecular "co-factors" as a way to target the androgen receptor differently in different cells, for instance, turning off the receptor in some cells while keeping it on in others, to fight prostate cancer. That type of cell-specific targeting is currently not possible.

The research in the laboratory involved tracking the disease in mice and also analyzing human prostate cancer cells in culture. Nevertheless, the work might include some hints for improving patient care. Possibilities include studying whether androgen suppression therapy might be used to target only specific cells within the prostate, as well as checking whether drugs designed to prevent cancer from spreading should be used in concert with hormone therapy.


'/>"/>

Contact: Leslie White
Leslie_White@urmc.rochester.edu
585-273-1119
University of Rochester Medical Center
Source:Eurekalert

Page: 1 2 3 4

Related biology news :

1. Risk of common vaginal infection linked to preterm birth appears higher for blacks
2. Features of replication suggest viruses have common themes, vulnerabilities
3. Genetics determine optimal drug dose of common anticoagulant
4. All eukaryotic kinases share 1 common set of substrates
5. 60 second test could help early diagnosis of common brain diseases
6. Soy isoflavone may inhibit common gastrointestinal illness in infants
7. The importance of gene regulation for common human disease
8. Genes and environment grant funds close look at nature-nurture overlap in common diseases
9. Thriving hybrid salamanders contradict common wisdom
10. UCI researchers restore memory process in most common form of mental disability
11. Drug commonly used to treat bipolar disorder dramatically increases lifespan in worms
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/17/2014)... Fauna Europaea started in 2000 as an EC-FP5 four-year ... years of steady progress and successful participations in several ... European Biodiversity Observation Network project (EU BON), to ... the contributors and to extend the general dissemination of ... Journal has applied its novel e-Publishing tools ...
(Date:9/17/2014)... plastic shopping bags and their environmental impact recently scored ... first statewide ban on the bags, and Governor Jerry ... bag industry is not yielding without a fight, according ... , the weekly newsmagazine of the American Chemical Society. ... that the anti-bag campaign logged its first small victory ...
(Date:9/17/2014)... Spanish researchers have obtained the first partial genome sequence ... pig found at the site of the Montsoriu Castle ... pig is closely related to today,s Iberian pig. Researchers ... with modern Iberian pigs. , The study, published in ... of pig species, and particularly on that of the ...
Breaking Biology News(10 mins):Contributions on Fauna Europaea: Data papers as innovative model on expert involvement 2Iberian pig genome remains unchanged after 5 centuries 2
... -- Scientists from The Forsyth Institute and Kings College, ... community, the Human Oral Microbiome Database, which provides descriptions ... commonly found in peoples mouths. Most bacteria living ... maintaining the health of teeth and gums, as well ...
... a biosensing nanodevice developed by Arizona State University ... airport security checkpoints and revolutionize health screenings for ... aureus (MRSA). Even more incredible than the ... the worlds tiniest rotary motor: a biological engine ...
... ... covert data -, LAKE WORTH, Fla., March 24 ... produce the,world,s first self-authenticating passport. It was introduced in the new,Belgian passport ... produces the Belgian passport,has added an optical decoder page in the passport ...
Cached Biology News:Scientists launch human oral microbiome database 2Biosensing nanodevice to revolutionize health screenings 2Biosensing nanodevice to revolutionize health screenings 3FCO and GSSC Team to Create World's First Self-Authenticating Passport 2
(Date:9/18/2014)... , Sept. 18, 2014  U.S. biotech company ... signing an exclusive license for technology developed by the ... gene expression in plants, including for applications in production ... The technology was developed under the direction ... at Kultevat and former president of the Danforth Plant ...
(Date:9/18/2014)... , Pennsylvanie, 18 septembre 2014 ... en 1974, a été depuis 40 ... les évaluations cliniques traditionnelles par des évaluations ... et sur les impacts économiques des traitements. ... A cours d,une récente ...
(Date:9/18/2014)... dysplasia is a group of rare diseases that ... cartilage. Its onset hits at the fetal stage ... in the gene encoding fibroblast growth factor receptor ... of skeletal dysplasia, thanatophoric dysplasia (TD), a skeletal ... and is often lethal, and achondroplasia (ACH), which ...
(Date:9/18/2014)... everything we touch in the course of a ... even medicines, rely on the chemical industry to ... and farm products into valuable chemicals that are ... scientist Dr Sarina Sarina, who achieved outstanding progress ... at ambient temperature using light instead of fossil ...
Breaking Biology Technology:Kultevat obtains license of gene switch technology 21974 - 2014 - Mapi fĂȘte ses 40 ans 2Researchers use iPS cells to show statin effects on diseased bone 2Researchers use iPS cells to show statin effects on diseased bone 3Using solar energy to turn raw materials into ingredients for every day life 2
... Sangart, Inc., a privately held biopharmaceutical company focused ... today announced the receipt of approximately $50 million in ... the exercise of warrants issued by Sangart as part ... The most recent investment brings the total funding ...
... WEST CONSHOHOCKEN, Pa., March 12 GEL Interactive ... today it will launch the most recent version of ... NV, March 23-25. GEL will be located in Booth ... its comprehensive event intelligence platform.GEL,s Immerse platform enables customers ...
... Inc. (TSX:SDI) today announced its operational highlights and financial ... , "In 2008, we accomplished several key objectives on ... sepsis for the U.S. market," said Dr. Paul Walker, ... to key terms with Toray Industries, Inc. (Toray) of ...
Cached Biology Technology:Sangart, Inc. Completes Series F Funding Round 2Cadient Group's GEL Interactive Technologies to Launch Immerse(SM) Exhibit 4.0 at EXHIBITOR2009 2Spectral announces 2008 financial results 2Spectral announces 2008 financial results 3Spectral announces 2008 financial results 4Spectral announces 2008 financial results 5Spectral announces 2008 financial results 6Spectral announces 2008 financial results 7Spectral announces 2008 financial results 8