Navigation Links
Whole-genome sequencing uncovers the mysteries of the endangered Chinese alligator

August 9, 2013, Shenzhen, China - In a study published in Cell Research, Chinese scientists from Zhejiang University and BGI have completed the genome sequencing and analysis of the endangered Chinese alligator (Alligator sinensis). This is the first published crocodilian genome, providing a good explanation of how terrestrial-style reptiles adapt to aquatic environments and temperature-dependent sex determination (TSD).

The Chinese alligator is a member of the alligator family that lives in China. It is critically endangered with a population of ~100 wild and ~10,000 captive individuals in Zhejiang and Anhui Provinces. Great efforts have been put into uncovering the mysteries of this species because of its unique features that allow them being adapted for living in both water and land habitats.

In this study, researchers collected a Chinese alligator sample from Changxing Yinjiabian Chinese Alligator Nature Reserve (Zhejiang Province, China) and sequenced its genome using a whole-genome shotgun strategy. The genomic data yielded a draft sequence of Chinese alligator with the size of 2.3 Gb, and a total of 22,200 genes were predicted.

The genomic data provides a strong evidence from DNA level to illustrate why Chinese alligator can hold its breath under water for long periods of time, such as the duplication of the bicarbonate-binding hemoglobin gene, positively selected energy metabolism, and others. Researchers further identified the genetic signatures of the powerful sensory system and immune system of Chinese alligator. All the results presented evidence for co-evolution of multiple systems specific to the back-to-the water transition.

Chinese alligator exhibits TSD, and does not possess sex chromosomes. The absence of sex chromosomes is another interesting feature. In this study, researchers analyzed the evolutionary mechanism of sex chromosomes, and reported that the alligator was the first TSD species whose genome has been sequenced, which will have great implication in resolving sex chromosome evolution.

Shengkai Pan, Project manager from BGI, said, "The accomplishment of the Chinese alligator genome is significant for understanding its adaptation for both aquatic and terrestrial environments, and more importantly, for the conservation of such an endangered species."


Contact: Jia Liu
BGI Shenzhen

Related biology news :

1. Powerful sequencing technology decodes DNA folding pattern
2. Sequencing works in clinical setting to help -- finally -- get a diagnosis
3. The sequencing of the tomato genome
4. DNA Sequencing: Emerging Technologies and Applications
5. Next-generation sequencing technology opens doors to discoveries
6. University of North Texas Health Science Center Advances Forensic Research by Investing in Semiconductor DNA Sequencing Technology
7. Exome sequencing gives cheaper, faster diagnosis in heterogeneous disease
8. An error-eliminating fix overcomes big problem in 3rd-gen genome sequencing
9. Exome sequencing of health condition extremes can reveal susceptibility genes
10. New genomic sequencing method enables smarter anaysis of individual cells
11. US-Russian collaboration develops new method for sequencing dark matter of life from a single cell
Post Your Comments:
(Date:6/14/2017)... (NYSE: IBM ) is introducing several innovative partner startups ... collaboration between startups and global businesses, taking place in ... nine startups will showcase the solutions they have built with ... France is one of the ... percent increase in the number of startups created between 2012 ...
(Date:5/16/2017)...  Veratad Technologies, LLC ( ), an innovative ... verification solutions, announced today they will participate as a ... thru May 17, 2017, in Washington D.C.,s ... Identity impacts the lives of billions ... evolving digital world, defining identity is critical to nearly ...
(Date:5/6/2017)... 2017 RAM Group , Singaporean ... breakthrough in biometric authentication based on a ... to perform biometric authentication. These new sensors are based ... by Ram Group and its partners. This sensor will ... chains and security. Ram Group is a next ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... ... October 12, 2017 , ... ... first-ever genomics analysis platform specifically designed for life science researchers to analyze ... pioneering researcher Rosalind Franklin, who made a major contribution to the discovery ...
(Date:10/11/2017)... Wayne. NJ (PRWEB) , ... October 11, 2017 , ... Personal eye wash is a ... rinse one eye at a time. So which eye do you rinse first if a ... you have Plum Duo Eye Wash with its unique dual eye piece. , ...
(Date:10/11/2017)... 2017  VMS BioMarketing, a leading provider of patient support ... Nurse Educator (CNE) network, which will launch this week. The ... health care professionals to enhance the patient care experience by ... other health care professionals to help women who have been ... ...
(Date:10/11/2017)... Austin, TX (PRWEB) , ... October 11, 2017 ... ... in August compared the implantation and pregnancy rates in frozen and fresh ... the contribution of progesterone and maternal age to IVF success. , After comparing ...
Breaking Biology Technology: