Navigation Links
Whole-genome sequencing uncovers the mysteries of the endangered Chinese alligator
Date:8/9/2013

August 9, 2013, Shenzhen, China - In a study published in Cell Research, Chinese scientists from Zhejiang University and BGI have completed the genome sequencing and analysis of the endangered Chinese alligator (Alligator sinensis). This is the first published crocodilian genome, providing a good explanation of how terrestrial-style reptiles adapt to aquatic environments and temperature-dependent sex determination (TSD).

The Chinese alligator is a member of the alligator family that lives in China. It is critically endangered with a population of ~100 wild and ~10,000 captive individuals in Zhejiang and Anhui Provinces. Great efforts have been put into uncovering the mysteries of this species because of its unique features that allow them being adapted for living in both water and land habitats.

In this study, researchers collected a Chinese alligator sample from Changxing Yinjiabian Chinese Alligator Nature Reserve (Zhejiang Province, China) and sequenced its genome using a whole-genome shotgun strategy. The genomic data yielded a draft sequence of Chinese alligator with the size of 2.3 Gb, and a total of 22,200 genes were predicted.

The genomic data provides a strong evidence from DNA level to illustrate why Chinese alligator can hold its breath under water for long periods of time, such as the duplication of the bicarbonate-binding hemoglobin gene, positively selected energy metabolism, and others. Researchers further identified the genetic signatures of the powerful sensory system and immune system of Chinese alligator. All the results presented evidence for co-evolution of multiple systems specific to the back-to-the water transition.

Chinese alligator exhibits TSD, and does not possess sex chromosomes. The absence of sex chromosomes is another interesting feature. In this study, researchers analyzed the evolutionary mechanism of sex chromosomes, and reported that the alligator was the first TSD species whose genome has been sequenced, which will have great implication in resolving sex chromosome evolution.

Shengkai Pan, Project manager from BGI, said, "The accomplishment of the Chinese alligator genome is significant for understanding its adaptation for both aquatic and terrestrial environments, and more importantly, for the conservation of such an endangered species."


'/>"/>

Contact: Jia Liu
liujia@genomics.cn
BGI Shenzhen
Source:Eurekalert

Related biology news :

1. Powerful sequencing technology decodes DNA folding pattern
2. Sequencing works in clinical setting to help -- finally -- get a diagnosis
3. The sequencing of the tomato genome
4. DNA Sequencing: Emerging Technologies and Applications
5. Next-generation sequencing technology opens doors to discoveries
6. University of North Texas Health Science Center Advances Forensic Research by Investing in Semiconductor DNA Sequencing Technology
7. Exome sequencing gives cheaper, faster diagnosis in heterogeneous disease
8. An error-eliminating fix overcomes big problem in 3rd-gen genome sequencing
9. Exome sequencing of health condition extremes can reveal susceptibility genes
10. New genomic sequencing method enables smarter anaysis of individual cells
11. US-Russian collaboration develops new method for sequencing dark matter of life from a single cell
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/8/2016)... , Dec. 8, 2016 Market Research Future published a ... The global Mobile Biometric Security and Service Market is expected to ... 2022. Market Highlights: ... , Mobile Biometric Security ... to the increasing need of authentication and security from unwanted cyber ...
(Date:12/8/2016)...  Singulex, Inc., the leader in Next Generation Immunodiagnostics ... license and supply agreement with Thermo Fisher Scientific, the ... access to Thermo Scientific BRAHMS PCT (Procalcitonin), a biomarker ... to diagnose systemic bacterial infection and sepsis and in ... in assessing the risk of critically ill patients for ...
(Date:12/7/2016)... , December 7, 2016 According to a new ... Learning), Software Tool (Facial Expression, Voice Recognition), Service, Application Area, End User, And ... estimated to grow from USD 6.72 Billion in 2016 to USD 36.07 Billion ... Continue Reading ... ...
Breaking Biology News(10 mins):
(Date:12/9/2016)... Westport, CT (PRWEB) , ... December 09, 2016 , ... ... a small percentage of sales to a charity, it not only donates 15%-20% of ... name brands are sold at the lowest factory-permitted prices. , At inception, over 50 ...
(Date:12/9/2016)... ... 09, 2016 , ... There’s a winning streak at Voxx Analytics: the tech ... after winning the award last year as well. Employees nominate their companies for the ... Vesely pointed to the tech company’s upbeat environment as a reason. “We don’t answer ...
(Date:12/9/2016)... ... ... DuPont Industrial Biosciences (DuPont) and Archer Daniels Midland Company ... Platts Global Energy for their platform technology to produce a revolutionary biobased monomer, ... Global Energy Awards, held in New York on Thursday, Dec. 8. , The ...
(Date:12/9/2016)... ... 2016 , ... Aditya Humad, Acting CFO of AxioMed and Managing Partner of ... States, Axiomed is now gaining interest from Silicon Valley. “It was satisfying to complete ... on to say that, “We expect interest to continue to rise as AxioMed completes ...
Breaking Biology Technology: