Navigation Links
Which came first, the chicken genome or the egg genome?
Date:10/8/2007

Which came first, the chicken genome or the egg genome?

Researchers have answered a similarly vexing (and far more relevant) genomic question: Which of the thousands of long stretches of repeated DNA in the human genome came first? And which are the duplicates?

The answers, published online by Nature Genetics on October 7, 2007, provide the first evolutionary history of the duplications in the human genome that are partly responsible for both disease and recent genetic innovations. This work marks a significant step toward a better understanding of what genomic changes paved the way for modern humans, when these duplications occurred and what the associated costs are in terms of susceptibility to disease-causing genetic mutations.

Genomes have a remarkable ability to copy a long stretch of DNA from one chromosome and insert it into another region of the genome. The resulting chunks of repeated DNA called segmental duplications hold many evolutionary secrets and uncovering them is a difficult biological and computational challenge with implications for both medicine and our understanding of evolution.

The new evolutionary history, published in Nature Genetics, is from an interdisciplinary team led by biologist Evan Eichler from the University of Washington School of Medicine and computer scientists Pavel Pevzner from University of California, San Diego.

In the past, the highly complex patterns of DNA duplication including duplications within duplications have prevented the construction of an evolutionary history of these long DNA duplications.

To crack the duplication code and determine which of the DNA segments are originals (ancestral duplications) and which are copies (derivative duplications), the researchers looked to both algorithmic biology and comparative genomics.

Identifying the original duplications is a prerequisite to understanding what makes the human genome
'/>"/>

Contact: Daniel Kane
dbkane@ucsd.edu
858-534-3262
University of California - San Diego
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Identification of specific genes predicts which patients will respond to Hepatitis C treatment
2. Overbearing colored light may reveal a second mechanism by which birds interpret magnetic signals
3. Bacteria which sense the Earths magnetic field
4. Researchers discover which organs in Antarctic fish produce antifreeze
5. First-ever genomic test predicts which lung cancer patients need chemotherapy to live
6. Researchers discover key mechanism by which lethal viruses Ebola and Marburg cause disease
7. Newts which regrow their hearts
8. Reminding doctors which antibiotics to prescribe cuts C. difficile infection rates
9. Killing the messenger RNA -- But which one?
10. Scientists discover stage at which an embryonic cell is fated to become a stem cell
11. First production of human monoclonal antibodies in chicken eggs published in Nature Biotechnology
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/11/2014)... South Wales, Australia when NASA,s Aqua satellite passed overhead ... 11 (12:35 p.m. local time/11:35 p.m. EDT on July ... (NSW), the Moderate Resolution Imaging Spectroradiometer (MODIS) aboard captured ... smoke (light brown) from various fires. Actively burning areas, ... , The New South Wales, Australia Government website "NSW ...
(Date:7/11/2014)... scientists have set a "mouse TRAP" to capture the ... recent study published in the Journal of Clinical ... technique called TRAP to extract cellular and genetic information ... scientists at the Rockefeller Institute for Medical Research in ... protein-making machinery, or ribosomes, of the cell type of ...
(Date:7/11/2014)... including scientists from the Max Planck Institute for Medical ... step in understanding photosynthesis, the process by which the ... its atmosphere and which is therefore crucial for all ... researchers report the first direct visualization of a crucial ... which a specific protein complex, photosystem II, splits water ...
Breaking Biology News(10 mins):A first direct glimpse of photosynthesis in action 2
... complex chemicals used by plants for defence and protection. ... that is found in most land plants. All ... single-celled organisms like amoeba, or enormous entities like Giant ... body of the organism). Although cells may become specialised ...
... technology launches today with the Nymi, from Bionym, ... graduates. The Nymi is the world,s first wearable authentication ... identity. The convenient and secure authentication is enabled through ... your personal ECG, it will communicate your identity to ...
... Evidence of diverse life forms dating back nearly a ... sediments by a group of British scientists., The possibility ... and dark lakes hidden kilometres beneath the Antarctic ice ... sampling of these lakes in the interior of Antarctica ...
Cached Biology News:New cell component important to tea and wine-making 2Nymi by Bionym launches using your unique heartbeat to unlock your world 2Life found in the sediments of an Antarctic subglacial lake for the first time 2
(Date:7/11/2014)... 2014 , Not for release, publication ... from any jurisdiction where to do so would constitute a ... Shire plc ("Shire" or the "Company") (LSE: SHP, NASDAQ: ... confirms it has held a meeting with representatives of AbbVie. ... the prior agreement or approval of AbbVie. A ...
(Date:7/11/2014)... 2014 /CNW/ - Sunovion Pharmaceuticals Canada Inc. (Sunovion) today ... acetate) for use as a once-daily adjunctive therapy for ... who are not satisfactorily controlled with conventional therapy.  APTIOM ... under 18 years of age. Epilepsy ... according to Epilepsy Canada, it affects 0.6% of the ...
(Date:7/10/2014)... (PRWEB) July 10, 2014 Product ... in very low abundance and are often “lost ... and time-consuming. , Join presenters Dr. Rowel Tobias, ... Dr. John Anders, Head of Quality at Nanotherapeutics, ... approach that can speed detection and quantitation while ...
(Date:7/10/2014)... CA (PRWEB) July 10, 2014 Unraveling ... closer together. The Archer Family purchased a ... within DNA, but ended up with a lifetime of ... contained within the family members’ DNA genuinely brought the ... decided to search deeper into genetic history and prior ...
Breaking Biology Technology:Shire plc - Statement re: Media Speculation 2Sunovion Pharmaceuticals Canada Inc. Announces Health Canada Approval of APTIOM(TM) (eslicarbazepine acetate) as a Once-Daily Adjunctive Treatment for Partial-Onset Seizures in Patients with Epilepsy 2Sunovion Pharmaceuticals Canada Inc. Announces Health Canada Approval of APTIOM(TM) (eslicarbazepine acetate) as a Once-Daily Adjunctive Treatment for Partial-Onset Seizures in Patients with Epilepsy 3Sunovion Pharmaceuticals Canada Inc. Announces Health Canada Approval of APTIOM(TM) (eslicarbazepine acetate) as a Once-Daily Adjunctive Treatment for Partial-Onset Seizures in Patients with Epilepsy 4Novel Ms Techniques Speed Detection of Biopharmaceutical Product and Process Impurities, New Webinar Hosted by Xtalks 2Ancestry DNA Test Reveals a Controversial and Undiscovered Family History 2Ancestry DNA Test Reveals a Controversial and Undiscovered Family History 3Ancestry DNA Test Reveals a Controversial and Undiscovered Family History 4Ancestry DNA Test Reveals a Controversial and Undiscovered Family History 5
... NEW AGREEMENT COVERS MARROWXPRESS(TM) IN KEY GLOBAL MARKETS, ... (Nasdaq: KOOL ), a leading supplier of ... stem cells, said today it has signed,a distribution ... line used for isolating stem cells from bone,marrow. ...
... LONDON, September 8, 2008 / b3c newswire ... not seem to have hit the European pharmaceutical industry ... as in past years, eyeforpharma’s upcoming Marketing Summit Europe, ... the biggest event of its kind ever. , ,Companies ...
... 3rd Largest Biotech Cluster By ... Developing more than 175 Local Companies, SAN DIEGO, Sept. ... Reunion for Hybritech employees will,take place on Saturday, September 13th, ... In September 1978 Hybritech, San Diego,s "Granddaddy" biotech company,began operations ...
Cached Biology Technology:ThermoGenesis Announces Distribution Agreement for Bone Marrow Stem Cell Device 2ThermoGenesis Announces Distribution Agreement for Bone Marrow Stem Cell Device 3ThermoGenesis Announces Distribution Agreement for Bone Marrow Stem Cell Device 4Eyeforpharma's Marketing Summit is shaping up to be the biggest event of its kind ever 2San Diego's Original Biotech Company Celebrates 30th Anniversary With Reunion 2
Rabbit polyclonal to LCAT ( Abpromise for all tested applications). entrezGeneID: 3931 SwissProtID: P04180...
Sheep polyclonal to Malate Dehydrogenase ( Abpromise for all tested applications). Antigen: Full length protein - Pig heart malate dehydrogenase. Entrez Gene ID: 4190 Swiss Protein ID: P...
Mouse monoclonal [7E10] to C Peptide ( Abpromise for all tested applications). entrezGeneID: 3630 SwissProtID: P01308...
...
Biology Products: