rcher for the study, Dr. Appleyard, These findings contribute to our understanding of how stress may affect the severity of endometriosis. We think there is likely a connection with the immune system because of the observed levels of mast cells in the colon and the increased levels of inflammatory cells in the peritoneum of the affected rats, since this has also been observed in patients with endometriosis. Appleyard continued, The results offer a jumping off point to help identify stress-management interventions that will help those women who are affected by the disease.