Navigation Links
When our skin fails to protect us
Date:3/20/2012

The skin is the body's largest organ and an indispensable part of the immune system. As the body's outermost line of defense against microbes, the skin provides important protection against potentially toxic environmental elements. One subset of immune cells, thymus-derived T-cells play an important role in the skin's response to injury, particularly with respect to wound healing. When epidermal T-cells do not respond effectively, non-healing wounds may result. The treatment of chronic wounds is the single most important contributor to skin-related health care costs in the elderly. Professor Thomas Krieg, Dean of the Medical Faculty and Principal Investigator in the Cluster of Excellence for Cellular Stress Responses in Aging-Associated Diseases (CECAD) at the University of Cologne, Germany, will address issues and treatments of chronic wounds, which are a challenge to patients and aging societies as a whole. Prof. Krieg's research at the University of Cologne's department of dermatology includes cell-cell and cell-extracellular matrix interactions as crucial components for the maintenance of healthy skin functions.

T-cells are also involved in the development of a wide range of autoimmune disorders that affect the skin and hair. Alopecia Areata, for example, is an organ-specific autoimmune disease in which T-cells attack human hair follicles and damage them with resulting hair loss. Dr. Angela Christiano, Richard and Mildred Rhodebeck Professor of Dermatology and Professor of Genetics & Development at Columbia University Medical Center, will discuss Alopecia Areata. Her major focus of research is the study of inherited skin and hair disorders in humans, through a classical genetic approach that include identification and phenotyping of disease families, genetic linkage, gene discovery and mutation analysis, and most recently, functional studies relating these findings to basic questions in epidermal biology.

Dr. David Bickers, Carl Truman Nelson Professor, Chair of the Department of Dermatology, College of Physicians & Surgeons of Columbia University Medical Center will moderate.

The event will take place on Monday, March 26, 6:30 to 8:30 p.m., at the German House New York (871 United Nations Plaza, First Avenue, btw. 48th & 49th Streets). It is organized in joint cooperation with the University of Cologne. Click here to RSVP. A video recording will be available on www.germaninnovation.org shortly after the event.


'/>"/>

Contact: Andrea Deierlein
deierlein@germaninnovation.org
212-339-8606
German Center for Research and Innovation
Source:Eurekalert

Related biology news :

1. When standard treatment fails: Jefferson to start unique immunotherapy for brain tumor patients
2. Sight fails when defective eye cells cripple renewal
3. MS study offers theory for why repair of brains wiring fails
4. Marine Protected Areas are keeping turtles safe
5. Building the European Unions Natura 2000 -- the largest ever network of protected areas
6. Improved Authentication and Confidentiality Protection. ICAP Patent Brokerage Announces for Auction Important Patents in Data Encryption and Document Security
7. Rising ocean temperatures harm protected coral reefs
8. Breakthroughs in Chikungunya research from A*STAR spell new hope for better treatment and protection
9. New study will help protect vulnerable birds from impacts of climate change
10. Protecting living fossil trees
11. Study IDs new marine protected areas in Madagascar
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/7/2016)... , June 7, 2016  Syngrafii Inc. and ... business relationship that includes integrating Syngrafii,s patented LongPen™ ... project. This collaboration will result in greater convenience ... credit union, while maintaining existing document workflow and ... ...
(Date:6/2/2016)... -- The Department of Transport Management (DOTM) of ... US Dollar project, for the , Supply and ... and IT Infrastructure , to Decatur ... of Identity Management Solutions. Numerous renowned international vendors participated in ... was selected for the most compliant and innovative solution. ...
(Date:6/2/2016)... Perimeter Surveillance & Detection Systems, Biometrics & ... & Other Service  The latest report from ... of the global Border Security market . Visiongain ... billion in 2016. Now: In November 2015 ... and hardware technologies for advanced video surveillance. ...
Breaking Biology News(10 mins):
(Date:6/27/2016)... June 27, 2016  Liquid Biotech ... funding of a Sponsored Research Agreement with The ... cells (CTCs) from cancer patients.  The funding will ... levels correlate with clinical outcomes in cancer patients ... will then be employed to support the design ...
(Date:6/24/2016)... ... 2016 , ... While the majority of commercial spectrophotometers and fluorometers use the ... models are higher end machines that use the more unconventional z-dimension of 20mm. ... the bottom of the cuvette holder. , FireflySci has developed several Agilent flow ...
(Date:6/23/2016)... , June 23, 2016   Boston ... of novel compounds designed to target cancer stemness ... has been granted Orphan Drug Designation from the ... treatment of gastric cancer, including gastroesophageal junction (GEJ) ... inhibitor designed to inhibit cancer stemness pathways by ...
(Date:6/23/2016)... , ... June 23, 2016 , ... ... YM (Yeast and Mold) microbial test has received AOAC Research Institute approval 061601. ... microbial tests introduced last year,” stated Bob Salter, Vice President of Regulatory and ...
Breaking Biology Technology: