Navigation Links
When cells hit the wall: UCLA engineers put the squeeze on cells to diagnose disease
Date:5/1/2012

lity in that regard."

With Rao and Dr. Otto Yang, a professor in the infectious diseases division at the Geffen School of Medicine and the department of microbiology, immunology and molecular genetics, the researchers found that in addition to identifying cancer, the technique was also sensitive to states of acute and chronic inflammation in which populations of white blood cells are primed to respond to infection. Measuring the state of the immune system can aid in diagnosing immune disorders such as AIDS or in evaluating patients' rejection of transplants early on, allowing doctors to modify anti-rejection therapies.

"The applicability to infectious diseases and organ transplantation is still theoretical," said Yang, who is also a researcher with the UCLA AIDS Institute. "Immune cells change physical characteristics as they are activated, and so, in theory, this technology could be harnessed to detect immune responses against infections or transplanted organs."

"Working with other folks across campus has been amazing," Di Carlo said. "Anytime we talked with Amander, Otto or Jian Yu, we learned something new which helped us refine our system and the problems we chose to address. We all live in slightly different worlds, and sometimes communication is difficult, but bioengineering is great in that we can communicate in different languages and bridge the engineering school to medicine and biology much more effectively."

The results were reported online in the journal Proceedings of the National Academy of Sciences of the USA and will be published in a forthcoming print issue of the journal. More information can be found at Di Carlo's laboratory website.


'/>"/>

Contact: Wileen Wong Kromhout
wwkromhout@support.ucla.edu
310-206-0540
University of California - Los Angeles
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Jefferson scientists deliver toxic genes to effectively kill pancreatic cancer cells
2. NSF funds new Center for the Physics of Living Cells at Illinois
3. When cells go bad
4. The role of stem cells in renewing the cornea
5. Breast cancer cells recycle to escape death by hormonal therapy
6. Models of eel cells suggest electrifying possibilities
7. Scientists identify a molecule that coordinates the movement of cells
8. Form of Crohns disease traced to disabled gut cells
9. Cold Spring Harbor Laboratory scientists trace a novel way cells are disrupted in cancer
10. Researchers design artificial cells that could power medical implants
11. Stabilizing force for good communication between neurons and muscle cells found
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/30/2014)... HONG KONG , Sept. 30, 2014 Winners of ... The Economist Events, Innovation Summit scheduled to take place at the ... At the summit, the award winners will share their experiences and ... people who have made a proven innovation over the past decade, ... the night before the summit. It will be the ...
(Date:9/29/2014)... A new study confirms that the exposure to tar ... than of regular cigarettes. Similarly, exposure to nicotine ... increasingly popular type of cigarette in several countries around ... of certain toxic chemicals in the smoke of these ... because lower levels of chemicals in the smoke are ...
(Date:9/29/2014)... Monday, September 29: Between 1970 and 2010 ... around the globe dropped 52 percent, says the ... Wildlife Fund (WWF). This biodiversity loss occurs disproportionately ... use of high-income countries. , In addition to ... data point to other warning signs about the ...
Breaking Biology News(10 mins):Hear from The Economist's 2014 Innovation Award Winners at Innovation Summit on October 10th in Hong Kong 2Hear from The Economist's 2014 Innovation Award Winners at Innovation Summit on October 10th in Hong Kong 3Hear from The Economist's 2014 Innovation Award Winners at Innovation Summit on October 10th in Hong Kong 4Hear from The Economist's 2014 Innovation Award Winners at Innovation Summit on October 10th in Hong Kong 5Hear from The Economist's 2014 Innovation Award Winners at Innovation Summit on October 10th in Hong Kong 6Hear from The Economist's 2014 Innovation Award Winners at Innovation Summit on October 10th in Hong Kong 7Slim cigarette smokers not exposed to more harmful chemicals 2Half of global wildlife lost, says new WWF report 2
... Alaska - University of Alaska Museum of the North ... summer working with a Norwegian research team to excavate ... of Svalbard. At the time, they knew the Jurassic ... conserving the specimen at the Natural History Museum at ...
... recently developed a new modeling approach to estimate sea ... on historical observations. The model was developed ... Russian Academy of Sciences, Moscow. Using this ... estimated from 1982 to 2003. Results showed that average ...
... endemic to healthy corals could change depending on the ... matter in seawater, report researchers from The University of ... Laboratory in Sarasota, Florida. Healthy corals naturally exude ... of bacteria exists. Recent studies have indicated that ...
Cached Biology News:International team announces discovery of massive Jurassic marine reptile 2New method to estimate sea ice thickness 2Dissolved organic matter in the water column may influence coral health 2
(Date:9/30/2014)... Lyme Research Alliance (LRA), the nation’s ... universities, today announced the awarding of seven grants worth ... cure for Lyme and other tick-borne diseases. , ... its history—over 20 grant proposals—a 100 percent increase from ... receive so many solid applications from talented scientists this ...
(Date:9/30/2014)... 2014 Rainbow Scientific, Inc. (RSI), ... recently opened an online store to add customer ... lines developed and manufactured by Biological Industries, Inc. ... Biological Industries’ Nutristem® serum-free, xeno-free reagents for human ... cell (hESC) culture. , The online store ...
(Date:9/30/2014)... (PRWEB) September 30, 2014 UFP ... and specialty packaging has recently introduced a custom ... Suspension Pack . The new insulated shipper solves ... chain distribution process. UFP Technologies’ BioShell is a ... bags during storage, handling and shipping. The insulated ...
(Date:9/30/2014)... Back in the 1970’s, many companies calculated ... employee, which included space for circulation and file storage. ... partner at Nidea Corporate Real Estate / ITRA Global ... year 2000, however, 250 square feet per employee became ... down to 175 to 225 square feet, and over the ...
Breaking Biology Technology:Lyme Research Alliance Awards Nearly $600,000 in New Grants 2Lyme Research Alliance Awards Nearly $600,000 in New Grants 3Lyme Research Alliance Awards Nearly $600,000 in New Grants 4Rainbow Scientific, Inc. opens online store for state-of-the-art stem cell culture and cytogenetic reagents 2UFP Technologies Introduces Insulated Shipping Container For Bulk Drug Transportation 2UFP Technologies Introduces Insulated Shipping Container For Bulk Drug Transportation 3ITRA Global Reports on How Companies Are Squeezing More Employees into Less Office Space 2ITRA Global Reports on How Companies Are Squeezing More Employees into Less Office Space 3
... Leading biotechnology,company Novozymes reports 13% sales growth in 2008. Earnings were ... an uncertain market.,Strong long-term trends lead to new, increased targets and ... - 2008 sales up by 13% in local currencies (LCY), ... - Sales growth of 5% in LCY and 10% ...
... number and dimension of particles or droplets as they actually exist ... and possibly unique, changes that are of critical importance to the ... with the knowledge, information and best practices you need to maximize ... ...
... AMSTERDAM, January 22 Avantium Technologies announces the,launch of ... industry. The system will be marketed under the name,Crystalline. ... designed to address the need in the pharma,industry to ... early in the,development cycle. , ...
Cached Biology Technology:Novozymes Reports Strong 2008 Results 2Maximize Data Analysis with METTLER TOLEDO FBRM 2Avantium Launches the Crystalline, a New Parallel System for Crystallization Research 2