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What's behind hypertension?
Date:8/1/2011

BETHESDA, Md. (Aug. 1, 2011) Each day we consume liquids in order to keep hydrated and maintain our body's fluid balance. But just as a water balloon can get overtaxed by too much liquid, the human body is negatively affected when it retains fluids because it is unable to eliminate them properly. One of the key variables influencing how much fluid we hold in our bodies is ordinary table salt (sodium chloride). The consequences of excess fluid retention can be severe, causing not only edema (excess of body fluid), but also high blood pressure (hypertension), which the Centers for Disease Control estimates affects nearly one in three American adults and last year carried an estimated financial toll of $76.6 billion for the period.

What is the connection between fluid balance and hypertension? The 7th International Symposium on Aldosterone and the ENaC/Degenerin Family of Ion Channels, sponsored by the American Physiological Society, explores this public health concern in detail. New scientific findings, coupled with talks by experts from around the world working in aldosterone and epithelial sodium channel (ENaC) research, is offering insight on the effect these substances have on blood pressure, the cardiovascular system and other organ systems. The meeting is being held September 18-22 at the Asilomar Conference Grounds in Pacific Grove, Calif.

Symposium on Aldosterone and the ENaC/Degenerin Family of Ion Channels

Aldosterone and ENaC can affect fluid regulation in several ways, according to symposium co-chair David Pearce, MD, division chief at San Francisco General Hospital and professor in the Division of Nephrology at the University of California, San Francisco. According to Dr. Pearce, "Aldosterone controls ENaC, the key sodium-transporting protein in the kidney tubule cells. It stimulates the amount of sodium reabsorbed by the body as regulated by ENaC," he said. "The more sodium and water there is in the body, the more c
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Contact: Donna Krupa
dkrupa@the-aps.org
301-634-7209
American Physiological Society
Source:Eurekalert

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